CHINESE MEDICINAL BIOTECHNOLOGY Bimonthly Established in December 2006 Responsible Institution Ministry of Health of the People’s Republic of China Sponsor China Medicinal Biotech Association 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Editing Editorial Board of Medicinal Biotechnology Chinese Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmbj01@126.com http://www.cmbp.net.cn Editor-in-Chief ZHAO Kai(赵铠) Managing Director YAN Ming(燕鸣) Publishing China Medicinal Biotech Association 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmba@cmba.org.cn Printing Beijing Zhongke Printing Limited Company Mail-Order Editorial Department of Chinese Medicinal Biotechnology 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmbj01@126.com CSSN ISSN 1673-713X CN 11- 5512 / R Copyright© 2007 by the China Medicinal Biotech Association Volume 2, Number 6 December 10, 2007 CONTENTS OF SELECTED ARTICLES Editorial Progress and prospect of human islet transplantation for treatment of diabetes ………………………………………………………… 401 CAI Han-qing, LOU Jin-ning Original Articles Effect of phospholipase inhibitor okadaic acid on HBV replication in HepG2.2.15 cells ……………………………………………… 405 PAN Xiao-ben, JI Ying, ZHU Ling, WANG Qian, GUAN Wen-li, HAN Jin-chao, WEI Lai Differentiation of mouse bone marrow mesenchymal stem cells induced by infarcted myocardium lysate in vitro ………………………… 411 ZHAO Jin-chao, GU Chun-hu, WANG Yun-ya, WEI Xu-feng , DONG Xiao-chao, LIU Jin-cheng, WANG Yun, YI Ding-hua In vitro cytotoxic and in vivo targeting effects of TCRVβ7.1 gene-modified T cells on liver cancer cells ……………………………… 416 LÜ Li-shan, WANG Jin-quan, SHAO Hong-wei, HUANG Shu-lin Rapid identification of mycobacterium by genes chips technique ……… 422 ZHAO Yuan, HU Zhong-yi, JING Feng-xiang, LIU Zhi-hui, WANG Jie, ZHENG Rui-juan, LU Jun-mei, ZHAO Hui, YIN Jun Interactions between sHLA-G1 and its receptors ILT2, and KIR2DL4 on NK-92 cells ……………………………………………… 428 WEI Jiao, ZHANG Hai-quan, YU Yan-rong, Muti-Ur-Rehman Khan, WANG Yun, DENG Li, FENG Mei-fu 125I seeds implantation as brachytherapy in nude mice bearing human breast cancer ………………………………………………… 435 CUI Xue-jun, LIU Zeng-li, ZHANG Zhi-yong, SHI Yi-zhen, TANG Jun, YANG Yi Expression of ezrin protein in gastric cancer and its clinical significance ………………………………………………… 441 LI Guo-fang, FENG Mao-hui, XIE Wei, GONG Ling-ling, CHENG Tian-tian Reviews Progress on Pin1-targeted antisense gene therapy for cancer …………… 445 SUN Huan-xing, SHAO Rong-guang Advancement in the research of puma in apoptosis promotion …………… 449 LIU Yong-jun, QIAN Hai-li, LIN Chen Progress on the function of IFN-λ family …………………………………… 452 LIU Xiao-jin, LI Ming-cai, SU Shao-bo Progress on the role of Wnt/β-catenin pathway in tumor stem cells …… 455 WEN Ping, HU Wei-hua, DOU Jun Progress on the application of thymidine kinase 1 to the diagnosis and prognosis of breast cancer …………………………………………………… 458 SHEN Jin-gen, ZHENG Li, JING Ning, XIONG Xiao-yan All articles published represent the opinions of the authors, not reflecting the official policy of the China Medicinal Biotech Association or the Editorial Board of Chinese Medicinal Biotechnology, unless this is clearly specified. Technology and Methods Application of immunoenzymatic technique to titration test of modified vaccinia Ankara virus …………………………………… 461 CHEN Dan, YU Liang, ZHANG Yin-chuan, ZHOU Dong-xia, HUANG Xiao-qin, CHU Jia-you Establishment and verification of neutralization method for smallpox vaccine Tiantan strain …………………………………………… 464 DONG Xiao-man, CHEN Xiu-zhen, DONG Yi, LÜ Yang Discussion and Contention Establishment of a biosafety management system in biosafety level 3 laboratories ………………………………………………… 467 LI Yong, LU Feng-min, ZHANG Feng-min, FU Jiang-nan, LAI Xiao-min, FAN Wei-min, XING Wen-ge, WANG Jian-hua