CHINESE MEDICINAL BIOTECHNOLOGY Bimonthly Established in December 2006 Responsible Institution Ministry of Health of the People’s Republic of China Volume 2, Number 5 October 10, 2007 CONTENTS OF SELECTED ARTICLES Sponsor China Medicinal Biotech Association Editorials Revival of biomedical capital ………………………………………………… 321 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Non-invasive imaging diagnosis of carotid plaque ………………………… 324 Editing Editorial Board of Medicinal Biotechnology ZHANG Shi-yuan ZHANG Wan-shi Chinese Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmbj01@126.com http://www.cmbp.net.cn Editor-in-Chief ZHAO Kai(赵铠) Managing Director YAN Ming(燕鸣) Original Articles Application of laser capture microdissection and microarray on analysis of differential gene expression in cancer …………………… 329 ZHANG Yun-fei, ZHANG Hua, ZHANG Bao-qun, WANG Hai-tao, CHEN Chao Effect of Forskolin on the expression and distribution of aquaporin8 in human WISH cells ……………………………………… 336 LU Wei, QI Hong-bo, HUANG Jin Effect of human cellular genomic DNA on the HBV DNA in the culture medium detected by real-time fluorescence quantitative PCR ………… 341 PAN Xiao-ben, HAN Jin-chao, ZHU Lin, GAO Yan, WEI Lai Publishing China Medicinal Biotech Association Expression of scFv-lidamycin fusion protein in Streptomyces globisporus C-1027 ……………………………………… 346 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmba@cmba.org.cn Quantitative determination of combining ratio of complete antigen for chloramphenicol …………………………………………………………… 351 Printing Beijing Zhongke Printing Limited Company Mail-Order Editorial Department of Chinese Medicinal Biotechnology 7B Zaojunmiao Road, Haidian District, Beijing 100081, China Tel: 0086-10-62135779 Fax: 0086-10-62115976 Email: cmbj01@126.com CSSN ISSN 1673-713X CN 11- 5512 / R Copyright© 2007 by the China Medicinal Biotech Association All articles published represent the opinions of the authors, not reflecting the official policy of the China Medicinal Biotech Association or the Editorial Board of Chinese Medicinal Biotechnology, unless this is clearly specified. LI Bao-wei, HU Yun-feng, WANG Li-fei, CUI Zhi-hui, HONG Bin, SHAO Rong-guang WANG Wen-jia, DONG Bin, TIAN Su-juan, YUAN Yin, HUANG Shu-lin Study on the uptake of 99Tcm-DTPA-DG by tumor cells after chemotherapy …………………………………………………………… 355 LIANG Jie, CHEN Yue, HUANG Zhan-wen, HE Ling, ZHAO Yan-ling In vivo study of bone formation of PDLLA/HA composite ……………… 360 LI Jian-hua, SHAN Xue-zhi, LI Shi-pu Study on ion-exchange membrane chromatography for purification of recombinant hepatitis B virus surface antigen ………………………… 365 YAO Wei, DUAN Li-juan, ZHANG Yan-rui, ZHANG Ying, REN Ya-ping, CUI Tie-min Reviews Progress in the mechanism of targeting of nanoparticles ………………… 370 ZHAO Jun-xian, ZHANG Ying-ge Advancement in the research on target antigens in anti-glomerular basement membrane disease ………………………………………………… 373 YANG Rui, ZHAO Ming-hui Advancement in the research on molecular diagnosis of lymphoma ……………………………………………………… 376 BI Rui, LÜ Ning Progress in the stability of structure of polypeptide drugs ………………… 380 GAO De-min, LIU Jin-feng, WANG Feng-shan Development on the physiological functions of soybean isoflavones and its separation and detection …………………………………………… 383 HAO Qing-nan, MA Chao, MA Bing-gang Studies on structure-activity relationship of endomorphins ……………… 387 GAO Yan-feng, ZHAI Ming-xia C-Jun N-terminal kinase and insulin resistance …………………………… 391 GUO Hong-hui, LING Wen-hua