December 2009

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CHINESE MEDICINAL BIOTECHNOLOGY

Bimonthly Established in December 2006 Volume 4, Number 6 December 10, 2009

Responsible Institution

Ministry of Health of the People’s

Republic of China

Sponsor

China Medicinal Biotech Association

7B Zaojunmiao Road, Haidian District,

Beijing 100081, China

Editing

Editorial Board of Chinese

Medicinal Biotechnology

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email: cmbj01@126.com http://www.cmbp.net.cn

Editor-in-Chief

ZHAO Kai (赵铠)

Managing Director

WU Zhao-hui

(吴朝晖)

Publishing

Publishing House,

Chinese Medicinal Biotechnology

7B Zaojunmiao Road, Haidian District,

Beijing 100081, China

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email: cmbj01@126.com

Printing

Beijing Zhongke Printing Limited

Company

Overseas Distributor

China International Book

Trading Corporation

P. O. Box 399, Beijing, China

Code No. BM4275

Mail-Order

Publishing House,

Chinese Medicinal Biotechnology

7B Zaojunmiao Road, Haidian District,

Beijing 100081, China

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email: cmbj01@126.com

CSSN

ISSN 1673-713X

CN 11- 5512 / R

Copyright© 2009 by the Publishing

House, Chinese Medicinal

Biotechnology

All articles published represent the opinions of the authors, not reflecting the official policy of the China

Medicinal Biotech Association or the

Editorial Board of Chinese Medicinal

Biotechnology, unless this is clearly specified.

CONTENTS OF SELECTED ARTICLES

Editorials

New curative effect of islet transplantation, to prevent or reverse diabetic vascularpathy …………………………………………

405

JIANG Yong-wei, SUI Wei-guo, CAI Han-qing, XU Shi-qing, LOU Jin-ning

Telomere, telomerase and the Nobel Prize …………………………………

408

LIU Zhong-min, LI Gang

Original Articles

Effects of mifepristone on aquaporin8 expression in the human amniotic epithelial cells …………………………………… 411

LI Yan, DUAN Zhao-ning, QI Hong-bo

Experimental study of inducing pancreatic stem cells differentiating into islet-like structures ………………………………………………………

417

XU Shi-qing, MEN Xiu-li, ZHANG Wen-jian, LOU Jin-ning, CAI Han-qing

Refolding of the ovarian anti-idiotypic single chain antibody 6B11ScFv and mouse HSP70 fusion protein expressed by E.coli

………………

424

ZHANG Guo, CHANG Xiao-hong, CHENG Ye-xia, YE Xue,

CHENG Hong-yan, WEI Li-hui, CUI Heng

Clinical observation of adoptive immunotherapy using autologous

CD3AK cells in treatment of advanced malignant tumor ……………

430

HAO Jian-feng, ZHANG Xiu-min, HU Pei-zhen, LI Xia, SUI Yan-fang

Study on the role of survivin-2B in apoptosis of tumor cell ………………

436

SHAO Hong-wei, ZHANG Wen-feng, HU Qing-lian, HUANG Shu-lin

Structure analysis of HBsAg produced by recombinant yeast cells

Hansenula polymorpha ………………………………………………………

441

LIU Chuang, ZHU Ting-yu, LI Jin, WANG Zhao, MA Rui, WANG Xi, YIN Chang-cheng

High resolution melting analysis of small amplicons and of mixing with a known genotype for genotyping of mitochondrial SNP13928G > C …………………………………………

445

ZHANG Jian-yi, FENG Jie, YANG Ze, HUO Zheng-hao

Reviews

Advances in the research on silk fibroins as drug controlled release carriers ………………………………………………………………… 449

YANF Li-qun, YANG Dan, MENG Shu, GUAN Yan-min, LI Jian-xin

Advances in the preparation and the application of pharmaceutical materials of HA ………………………………………

452

WANG Chao, ZHANG Ming-chun

The response signal pathway of unfolded proteins ………………………

455

LIU Li-li, GUO Qi-yu

The application of cyclodextrins and its derivatives in nanoparticles ………………………………………………………………

458

WANG Kai-yuan, GAO Yong-liang

The effect of the liquid surface tension on moulding of dropping pills ………………………………………………………………

461

LIU Yong, REN Lu-hua, QÜ Yun-zhi

Discussion and Contention

Overviews on the international competitiveness of researches, developments, manufacture of drugs in China …………………………

465

LU Da-yong, LU Ting-ren, WU Hong-ying

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