STUDY GUIDE – Biology UNIT 4
Chapter 10 Cell Growth and Division
Outcome 4:
Students will explain the somatic cell cycle in reference to cell growth, division, cancer, and stem
cells and illustrate cells in different phases of the cell cycle.
I. Cell Growth (sec 10-1) Explain why cells divide in reference to surface area and volume,
DNA over load, and exchange of materials.
A. Two factors the limit cell growth, which causes cell to divide.
1. DNA overload - ___________________________________________
2. Exchange of Materials - _____________________________________
B. Explain how the surface area (SA) relates to volume (V) in a cell as it grows.
_______________________________________________________________
_______________________________________________________________
1. As a cell increases in size, which increases more rapidly, its surface
area or its volume?________________
2. How is the problem of cell growth solved? _____________
II. Cell Division (sec 10-2) Analyze and describe key events occurring during interphase,
mitosis, and cytokinesis.
A. Chromosomes
1. What is chromatin? ________________________________
a) When is it visible? ___________________________
2. Chromosomes are only visible during __________________
a) Consist of 2 identical _________________________
b) Held together by a ___________________________
3. How many chromosomes does a human cell have _________
B. Cell Cycle
1. Interphase (Below name the 2 key thing that happen in this phase)
a) Cell ___________________
b) DNA __________________
2. Cell Division
a) Mitosis is the division of ____________________________
b) What is the role of the centrioles and spindle fibers?
__________________________________________________
__________________________________________________
c) Cytokinesis is the division of _________________________
* Plant forms a ________________________
d) Result of cell division is 2 ____________________________
C. Complete Chart titled “Cell Cycle” in study guide
1. See chart on next page
III. Stages of Cell Cycle (10-2) Locate and identify cells in different stages of the cell cycle
(interphase, prophase, metaphase, anaphase, telophase, and cytokinesis
a. See diagram on next page
IV. Regulating the Cell Cycle (10-3) Explain how cyclins regulate the cell cycle and
describe how cancer is related to an unregulated cell division.
A. Controlled Cell Division
1. Explain what is happening in the Petri dish below _____________
_______________________________________________________
2. How does that experiment relate to what happens in the
body when we have a cut? _________________________________
________________________________________________________
B. Cyclins
1. What are cyclins? _______________________________________
2. Give examples of internal regulators: _______________________
3. Give examples of external regulators: _______________________
C. Analyze factors that are related to the formation of cancer cells.
1. What causes cancer? ____________________________________
a) Benign is ________________________________________
b) Malignant is _____________________________________
c) Metastasize is ____________________________________
D. Research adult and embryonic stem cells comparing and contrasting harvesting
methods, medical benefits and problems, and moral issues (explanation of Catholic
Church’s position) .
1. What are they? ___________________________________________
__________________________________________________________
2. What are the benefits? _____________________________________
_______________________________________________________
3. What are the problems? ____________________________________
________________________________________________________
VOCABULAR TERMS (14 total)
CELL DIVISION
PROPHASE
CHROMATID
METAPHASE
CENTROMERE
ANAPHASE
CENTRIOLE
TELOPHASE
SPINDLE
CYTOKINESIS
INTERPHASE
MITOSIS
CELL CYCLE
CANCER
ROOT TERMS
pro
meta
telo
inter
centro
first
middle
end
between
center
prophase
metaphase
telophase
interphase
centromere