VOLUME 26, NO. 1 SPRING 1994 UPDATE Or4 HIV/AIDS THE AIDS TESTING EXPERIENCE OF A MAJOR COMPANY Linda Alexande~ MD Prudential Insurance Company has been testing applicants for antibodies to HIV since 1987. Over the past two years Prudential’s Eastern Operations Center, located in Fort Washington, Pennsylvania, has compiled demographic data on HIV positive applicants. These include applicants from Maine, Vermont, New Hampshire, Rhode Island, Massachusetts, Connecticut, New York, New Jersey, Pennsylvania, Maryland, Delaware, and Washington, D.C. From June 1,1991 to May 31,1992 (hereafter referred to as 1992 data), 48,884 applicants underwent initial screening with the serum ELISA (Enzyme-Linked ImmunoSorbant Assay). Between June 1,1992 and May 31, 1993 (hereafter referred to as 1993 data), 42,606 initial serum screens were performed. Reactive ELISA samples were re-tested in duplicate, and if reactive, were subjected to confirmatory Western Blot testing using accepted FDA protocols. All testing was performed by the GIB Laboratories located in New Providence, New Jersey. All results were verified by the Laboratory Director and the Medical Director. Data Analysis lowed by the 36-40 and 31-35 ranges. Among females in 1992 the greatest number of positives was also in the 26-30 age ranged, followed by the 31-35 and 36-40 ranges. In 1992 the greatest number of positives among males was in the 36-40 age range, followed by the 31-35 and 26-30 age ranges. Among females in 1993 the greatest number was in the 31-35 age range followed by the 36-40 and 41-45 age range. Figure 2 looks at male and female applicants by marital status. Of interest is the fact that the increase in the percentage of single males from 1992 to 1993 reflects an absolute decrease in the number of married male HIV positive applicants rather than in increase in the number of single male HIV positive applicants. In 1992 of 58 HIV positive male applicants in this screened population 25 were married and 24 were single. In 1993 the comparable numbers were 11 married males and 21 single males. Among females in 1992 there were 11 married and 10 single. In 1993 there were 9 married females and 12 single females. Figure 3 provides a breakdown by policy amount for those applicants who were initially screened by serum testing. The policy amount was not available in 5 cases. Figure I compares HIV positive results by age and sex for 1992 and 1993. In 1992 there were 90 confirmed positives among the 48,884 specimens screened by se- Figure 4 demonstrates state of residence. The greatest rum initially. This was comprised of 58 males and 32 number of positives was seen in applicants from New York and New Jersey. females, or 64% males and 36% females. In 1993 there were 64 confirmed positive among 42,606 specimens screened by serum initially. This was comprised of 46 males and 28 females, or 56 % males and 44 % females. Figure I breaks down male and female results further by age range. In 1992 among males the greatest number of positives was in the 26-30 and 41-50 age ranges, fol- V’~ce President, Medical Services, Prudential Insurance Company of America, Fort Washington, Pennsylvania. 28 Figure 5 calculates the prevalence of HIV positives broken down by sex among the tested population of applicants for life insurance in the states listed above who were initially screened by serum testing. Of interest are the prevalence rates of females compared to males of 22 per 10,000 vs. 17 per 10,000 in 1992 and 20 per 10,000 vs. 13 per 10,000 in 1993. JOURNAL OF INSURANCE MEDICINE VOLUME 26, NO. 1 SPRING 1994 Figure 1 1992/1993 ComFarison - HIV Positive Count by. Sex and Age Male Female 1992 15-20 21-25 26-30 31-35 36-40 41-45 46-5O 51.55 56-60 61-65 66-70 Count 0 3 16 7 11 14 4 2 0 1 0 10 1993 % 0.0 5.2 27.6 12.1 19.0 24.1 6.9 3.4 0.0 ¯ 1.7 0.0 100 Count 0 1 5 8 14 3 3 1 1 0 0 36 1992 % 0.0 2.8 13.9 22.2 38.9 8.3 8.3 2.8 2.8 0.0 0.0 100 Count 32 1993 % 0.0 9.4 28.1 21.9 15.6 9.4 6.3 6.3 0.0 0.0 3.4 100 Count 0 0 3 9 7 5 3 1 0 0 0 % 0.0 0.0 10.7 32.1 25.0 17.9 10.7 3.6 0.0 0.0 0.0 100 Male Applicants 7 6 4 2 15-20 21-25 26-30 31-35 36-40 41-45 46-50 51-55 56-60 61-65 AGE OF APPLICANTS ~ I~2 [Z3 1993 20 66-70 Female Applicants 15 I0 5 0 15-20 21-25 26-30 31-35 36-40 41-45 46-50 51-55 56-60 61-65 AGE OF APPLICANTS ~ 1992 V--] 1993 66-70 Note: All data collected at The Prudential’s Eastern Home Office. June 1st to May 31st reflects one year. 29 VOLUME 26, NO. 1 SPRING 1994 UPDATE ON HIV/AIDS Figure 2 1992/1993 Comparison -- Marital Status of HIV Apylicants by Sex Male Percentage 1992 1993 Count Married Single Divorced Separated Widowed 25 24 6 3 0 Female Percentage 42.6 40.7 11.1 5.6 0 1992 1993 Count % Count % Count 11 21 2 2 0 30.6 58.3 5.6 5.6 0 11 10 2 6 3 34.4 31.3 6.3 18.8 9.4 9 12 4 3 0 32.1 42.9 14.3 10.7 0 Male Applicants 70 50 40 30 20 10 0 Married Single Divorced Separated Widowed Separated Widowed MARITAL STATUS ~ 1992 ~ 1993 Female Applicants 50 40 30 20 10 0 Married Single Divorced MARITAL STATUS 1 1992 ~ 1993 Note: All data collected at The Prudential’s Eastern Home Office. June 1st to May 31st reflects one year. 3O JOURNAL OF INSURANCE MEDICINE VOLUME 26, NO. 1 SPRING 1994 Figure 3 199r2/1993 Comparison ~ HIV Positive Results by Polio. Amount 5,000 5,001-9,999 10,000 10,001-24,999 25,000 25,001-49,999 50,000 50,001-59,999 60,000 60,001-69,999 70,000 70,001-79,999 80,000 80,001-89,999 90,000 90,001-99,999 100,000 100,001-120,000 120,001-139,999 140,000-149,999 150,000 150,001-190,000 190,001-199,999 200,000 200,001-250,000 >250,000 Total Figure 4 Applicants State of Residence 1992 1993 0 0 6 3 6 2 5 1 1 0 0 3 0 1 0 0 8 1 9 2 6 9 1 6 7 8 85 2 0 4 1 6 2 2 0 12 1 1 2 0 0 0 0 11 1 5 2 3 4 2 0 2 1 64 State 1992 1993 New York New Jersey Maryland Pennsylvania Massachusetts Washington D.C. Connecticut New Hampshire Delaware Maine Rhode Island Vermont 61 13 7 2 3 2 1 1 0 0 0 0 31 18 5 6 1 0 0 1 1 1 0 0 Total 90 64 Note: All data collected at The Prudential’s Eastern Home Office. June 1st to May 31st reflects one year. Figure 5 Prudential (EHO) Composite Data 1992 Total Test Results Total Tests # of positive specimens % of positive specimens Male 33,9894 58 0.17% Female 14,860 32 0.22% 48,844 90 0.18% 14,114 28 0.20 42,606 64 0.15% 1993 Total Test Results Total Tests # of positive specimens % of positive specimens Male 28,492 36 0.13% 31