5.3.12.D.2 2011 5.3 Life Science: Life science principles are powerful conceptual tools for making sense of the complexity, diversity, and interconnectedness of life on Earth. Order in natural systems arises in accordance with rules that govern the physical world, and the order of natural systems can be modeled and predicted through the use of mathematics. D. Heredity and Reproduction: Organisms reproduce, develop, and have predictable life cycles. Organisms contain genetic information that influences their traits, and they pass this on to their offspring during reproduction. Essential Questions Enduring Understandings How is genetic information passed through generations? There are predictable patterns of 5.3.12.D.2 inheritance, and the variation that 1. Students assemble a fragment of the DNA nucleotides exists within a species is related to cut from different colored paper. By using the mRNA/ its mode of reproduction (sexual Amino Acid coding chart, students write down a or asexual). sequence of Amino Acids, coded by the fragment of the DNA they have created. Then students imitate various types of mutations, such as deletions, insertions, inversions, by removing or Cumulative Progress adding DNA nucleotides to the existing DNA fragment. Indicators Students have to decode a new Amino Acid sequence Predict the potential impact on an and write it down for their classmates’ analysis. They organism (no impact, significant will arrive to conclude that some mutations are neutral, impact) given a change in a therefore; have no effect onto the organism, and other specific DNA code, and provide mutations led to a very different order of amino acids, specific real world examples of and therefore different proteins with very different conditions caused by mutations. properties. (5.3.12.D.2) Content Statements Inserting, deleting, or substituting DNA segments can alter the genetic code. An altered gene may be passed on to every cell that develops from it. The resulting features may help, harm, or have little or no effect on the offspring’s success in its environment. Labs, Investigation, and Student Experiences 2. Fruit flies are very well known genetic study model organism that can be used to study mutagenic effect of cell phone radiation. Flies can be exposed to the cell phone or computer onto the Drosophila development/phenotypes/ rate of reproduction. 3. Students will research effects of radiation on human 1 5.3.12.D.2 2011 Desired Results Students will be able to… 1. Explain the cell cycle, how it contributes to reproduction and maintenance of the cell and/or organism, and explain where mitosis fits into the cell cycle. 2. Understand the factors that cause cells to reproduce. 3. Be able to describe each phase of mitosis and make a simple labeled drawing of mitosis. Indicate that resulting cells contain an identical copy of genetic information from the parent cell. 4. Explain how the apportioning of cytoplasm to the daughter cells follows mitosis, a nuclear eve nt. 5. Compare and contrast asexual and sexual types of reproduction that occur on the cellular and multicellular organism levels. Understand how asexual reproduction differs from sexual reproduction. Know the advantages and disadvantages of each. 6. Explain through the use of models or diagrams, why sexuallyproduced offspring are not identical to their parents. 7. Describe the events that occur in each meiotic phase. 8. Compare mitosis and meiosis; cite similarities and differences 9. Recognize that during the formation of gametes, or sex cells (meiosis), the number of chromosomes is reduced by one half, so that when fertilization occurs the diploid number is restored. 10. Recognize random mutation (changes in DNA) and events that occur during gamete formation and fertilization (i.e., crossing over, independent assortment and recombination of chromosomes) as the sources of heritable variations that give individuals within a speciessurvival and reproductive advantage or disadvantage over others in the species. 11. Explain why sex-linked traits are expressed more frequently mutagenesis (Hiroshima, Bikini Bottom Island, Chernoble, etc.) and dysfunctions that it might bring up. 4. Students can research on genetically altered food and, if possible, provide either samples or images of native fruit/vegetable and genetically modified fruits/vegetables. One of the examples would be a pear of a regular size and a polyploidic large-size pear. 5. Students can grow plant Arabidopsis and expose it to the UV-light as a source of mutations, and then analyze how the plant growth and development might be affected. The most common antibiotic resistant bacteria can be grown on the agar, and one batch serves as control, and another batch of bacteria can be exposed to the UV-radiation or any other mutagenic factor. Students will grow exposed bacteria and count colonies of bacteria that cannot grow in the presence of antibiotics, indicating that bacteria underwent a mutation and cannot grow in the presence of the agent. 2 5.3.12.D.2 2011 in males. 12. Compare and contrast the processes of growth (cell division) and development (differentiation). 13. Recognize that any environmental factor that influences gene expression or alteration in hormonal balance may have an impact on development. 14. List some of the problems in cell division when control is lost. 15. Recognize that cancer is a result of mutations that affect the ability of cells to regulate the cell cycle. 16. Describe early embryonic development and distinguish each: oogenesis, fertilization, cleavage, gastrulation and organ formation. 17. Describe the structure and function of the human male and female reproductive systems. 18. Model a random process (e.g., coin toss) that illustrates which alleles can be passed from parent to offspring. 19. Describe the relationship between DNA, genes, chromosomes, proteins and the genome. 20. Explain that a gene is a section of DNA that directs the synthesis of a specific protein associated with a specific trait in an organism. 21. Use Punnett squares, including dihybrid crosses, and pedigree charts to determine probabilities and patterns of inheritance (i.e. dominant/recessive, co-dominance, autosomal/sex-linkage, multiple-allele inheritance). 22. Analyze a karyotype to determine chromosome numbers and pairs. Compare and contrast normal and abnormal karyotypes. 23. Explain how sex chromosomes inherited from each parent determines the gender of the offspring. 3 5.3.12.D.2 2011 PERFORMANCE ASSESSMENT “Designing a Controlled Experiment: Growing tomatoes” OVERVIEW New Jersey is famous for its tomatoes. One of the most famous varieties of tomatoes is the “Rutgers,” which was introduced in 1934 by Rutgers breeder Lyman Schermerhorn. It was a top performing tomato for New Jersey’s canning industries, including Campbell’s and Heinz. The Rutgers tomato was the preferred choice of 75 percent of commercial growers for the rest of the twentieth century, and was used worldwide. Although it has now been replaced with newer varieties, it is still very popular with home gardeners. Tomatoes require warm weather to grow well. They are usually grown from May through September. Depending on the weather, tomatoes may be ripe for picking from July through September. Most commercial plant growers start tomato seeds growing in heated greenhouses in winter to get an early start on the growing season. They then either sell the young tomato plants to other commercial growers or home gardeners, or plant them outside in late spring and grow the tomatoes themselves. 4 5.3.12.D.2 2011 YOUR TASK You are the owner of a plant nursery that intends to grow a large number of Rutgers tomato seedlings this coming winter to sell to home gardeners in the spring. This fall you are going to conduct an experiment to determine the optimum growth conditions that will produce the best seedlings. Then you will use these conditions in the winter to grow your tomato seedlings for the coming season. Like all plants, tomato growth is determined by several factors: light, water, temperature, and soil type. The following materials are available to you: Rutgers tomato seeds, small pots, thermometers, meter sticks, sand, loam, four greenhouses with heat/lights/water You are to design a controlled experiment in which you determine: 1. How much water per day makes the tomatoes grow the best? 2. How many hours of light per day makes the tomatoes grow the best? 3. What temperature makes the tomatoes grow the best? 4. Which soil, sandy or loamy, makes the tomatoes grow the best? In describing your experiment, 1. Draw a chart depicting the basic design of your experiment. 2. Explain how you will determine what “best” is. 3. Explain how you will determine how each factor affects growth. 4. Use the following biological concepts and terms in your explanation: observation, hypothesis, inference, control group, experimental group, independent variable, dependent variable. 5 5.3.12.D.2 2011 DATA Greenhouse Diagram Top View Water source with hose Water source with hose Tables Side View Lights Thermostat Tables Thermostat 6