الجامعة اإلسالمية – غزة Islamic University-Gaza كلية التمريض Faculty of Nursing Name: Pathophysiology, Final Exam 20/5/2012 Number : I- Mention Two Complications of the following Time: 2 hours diseases (10 points) 1-Measles 2- Gastroesophageal Reflux Disease 3- Peptic ulcer 4-Renal calculi 5-Hypertension II- Mention ONLY TWO risk factors for 1-Breast cancer 2-Diabetes mellitus type 2 3-Adult kidney cancer 4-Coronary artery disease 5-Respiratory Distress Syndrome III–Define the following 1- Papilledema 2- Hemophilia A 3- Myocardial Infarction 4- Goiter 5- Cerebral Vascular Accident (5 points) (10 points) IV- Mention in short (10 points) - Cells that reproduce throughout a lifetime - The forces that together produce a decubitus ulcer - Renal Endocrine Function - Classes of Immunoglobulins - Backward Effects of Right Heart Failure V-What are the main clinical manifestation of the following (10 points) 1-Meningitis 2-Hirschsprung's Disease 3-Glomerulonephritis 4-Acute leukemia 5-Hypothyroidism (congenital megacolon) VI- Mention the Preventive measures in the following diseases (5 points) 1-measles 2-Impetigo 3-Colorectal Cancer 4-Spina bifida 5-Rheumatic fever VII- Put ( ) or ( X ) opposite each statement (10points) ( )-Failure to detect a tumor cell marker means that an individual is cancer-free ( )-plasma protein concentration increases with liver disease ( )-Lactose malabsorption results in osmotic diarrhea and flatulence . ( )-Rebound tenderness is a classic symptom of peptic ulcer. ( )-A second-degree burns is extremely painful and blisters within minutes. ( )-An early sign of decubitus ulcer is redness that does not disappear with fingertip pressure (non-blanching). ( )-Serum creatinine is not indicative of renal function ( )-There is the lack of sputum production in chronic bronchitis . ( )-Right-to-Left Shunt is called an acyanotic shunt ( )-With removal of the lactic acid, the pain of angina goes away VIII- MATCH (5 points) ( )-Is the collection of a plasma filtrate in the scrotum. a-Hydrocele ( )-Is the failure testicles to descend into the scrotum . b- Varicocele ( )- the opening of the urethra is on the ventral side of the penis. c- Cryptorchidism ( )- is the loss of 3.5 g or more of protein in the urine per day. d- Hypospadias ( )-It is an abnormal dilation of a vein in the spermatic cord e-Nephrotic Syndrome IX- Fill the following spaces with proper words (25 point) *-------------------------is histologic assessment of the tumor based on the degree of anaplasia. *-----------------------------is the movement of cancer cells from one part of the body to another. *- -----------------------------------------------is monosomy of the sex chromosomes *----------------------------is a scar formation on the skin, occurring after a trauma. *- ---------------------------------------is a generalized edema due to hypoalbuminemia. *-The respiratory response to renal acidosis is called----------------------------*--------------------------------------------------result from either ABO or Rh incompatibility between the infant and the mother. *- -------------------------------is a protrusion of a part of the stomach through the diaphragm. *-The collapse of previously expanded alveoli is called--------------------------*-Infections caused by any microorganism of the nongas-exchanging upper structures is called-----------------------------------------*-A tension pneumothorax is treated immediately with---------------------------*-Hypoxia, hypercapnia and acidosis are known as-------------------------------*---------------------------------------Is a chronic obstructive disease characterized by loss of lung elasticity and a reduction in alveolar surface area . *- --------------------- ------------------------is an aching, cramping feeling in the lower extremities due to muscle ischemia. *------------------------------is a dilation of the arterial wall. *- Increase in the pulse pressure is characteristic of -------------------------------------. *-The most common cardiac congenital defect is -----------------------------------------------. *- Painful menstruation that occurs without evidence of pelvic infection or disease is called-----------------------------------------------------. *------------------------------------------------is the absence of a menstrual cycle in a woman who has never had a menstrual cycle. *---------------------------------- is the failure of one or both testicles to descend into the scrotum . *------------------------------------------is the inability or reduced ability to produce offspring. *- the enlargement of breast tissue in males is called--------------------------------------. *------------------------------------------------------ Is the non-cancerous enlargement of the prostate . *---------------------------------------------- is a progressive loss in the transparency of the lens. X- MCQ (10 points) ( ) The following are Normal blood values EXCEPT: a-pH : 7.35-7.45 , b-PaO2 : 80-100 mmHg , c-PaCO2:45-55mmHg, d-HCO3 : 22-26mEq ( ) If ph = 7.18 , PaCO2 = 38, PaO2 = 70and HCO3 = 15 the case is suffering from a-Respiratory acidosis b-Respiratory alkalosis c-Metabolic acidosi d-Metabolic alkalosis ( ) If pH = 7.6 , PaCO2 = 30, PaO2 = 60and HCO3 = 22 the case is suffering from a-Respiratory acidosis b-Respiratory alkalosis c-Metabolic acidosi d-Metabolic alkalosis ( ) In Spermatogenesis, the following is true EXCEPT a-begins during puberty c-occurs in the seminiferous tubules b-continues throughout d-affected by LH the lifetime ( ) In Menopause, the following is true EXCEPT a-lack of the cycles for the previous 2 months. b- ovaries no longer release an ovum c-ovaries no longer produce estrogen and progesterone d-no LH and FSH are released ( ) Causes of malabsorption include: a- pancreatic digestive enzyme deficiency. b - genetic deficiencies in specific enzymes c- impairment of bile production. d- microorganism infection ( ) Nephrotic Syndrome manifestation includes a- loss of 3.5 g or more of protein in the urine per day. c-usually indicates severe glomerular damage. d-diabetic nephropathy is the most common cause e- all are true f- a+c b-generalized edema e- all f- a+d ( ) Causes of Prerenal failure include EXCEPT a-myocardial infarct b-an anaphylactic reaction, c-hypervolemia d-a burn, e-sepsis (a blood-borne infection). ( ) Childhood Kidney Cancer( Wilms' Tumor) a-develops in children younger than 4 years of age. b-It can grow to a large size. c-It may be encapsulated d-overall prognosis is bad. ( ) In Acute Pancreatitis,the following is true EXCEPT a-is an autodigestion of the pancreas by pancreatic enzymes. b- usually caused by a gallstone in the common bile duct. c- Hyperglycemia d-the usual presenting symptom is pain, often in the epigastric area after a large meal e- Vomiting and nausea may occur. e-low levels of serum amylase and lipase. XI-Bonus:What is inflammation of the following organs called(5 points) 1-ovary: 2- urinary bladder: 4-brain 5- testis 3-kidney : GOOD LUCK