Calculation of Summary Effects Using Random Effects Method
Instructions:
1. Double Click on the Table to Activate the Excel Spreadsheet
2. Enter the number of studies in the blue space.
3. Enter All Studies between the first and last studies only
 Select the Row marked the “Last”
 Click “Insert” > click “Rows”…A Row will be inserted between the first and last
 Now Copy the Row marked “last” and then paste it in the blank row just inserted
4. Now Change the figures only for the following:
 Diseased (Exposed) indicates all disease or outcome events (e.g. death,
recurrence or some other event) in the exposed or in the treatment group
 Diseased (Non-exposed) indicates all disease or outcome events in the nonexposed or the control group
 Non-diseased (Exposed) indicates all events which are compared to the disease or
outcomes of interest that occur in the exposed or treatment group
 Non-diseased (Non-exposed) – all events compared to the disease or outcomes of
interest in the non-exposed or control group
5. The Highlighted Yellow Section Will Show the Results and The Summary Estimate
6. If you make any mistake in steps 2 and 3 or the spreadsheet doesn’t work, exit without saving
changes and reopen.
Calculation of Effect Measure in Meta-analysis Using Random Effects Model
Add or Delete Studies Between the First and the Last Studies only
0.57
0.68
0.47
-5.78
1.00
0.43
2.00
Random Effects OR
95% CI (Upper)
95% CI (Lower)
Q-Statistics
degree of freedom
MH Odds Ratio:
No. of Studies
117.67
51.18
0.02
sumwts
sumprods
varmh
Study
Disease (exposed)
First
Last
100.00
100.00
Disease (non-exposed)Non-diseased (exposed)Non-diseased (non-exposed)
200.00
200.00
245.00
152.00
157.00
183.00