Facilitated Diffusion What is facilitated diffusion? • Facilitated diffusion is a passive form of transport meaning no energy or ATP is used by the cell. • In facilitated diffusion large molecules move through a cell membrane down their concentration gradient (move from a high concentration to a low concentration) by means of protein channels. •The cell membrane is a semi-permeable membrane that contains the contents of the cell. protein channels • protein channels are parts of the cell membrane that assist certain ions to move into and out of the cell. protein channels • protein channels are needed when a substance cannot pass through the cell membrane on its own. Protein channels provide a passageway for these substances to move in and out of the cell almost like a tunnel. • Glucose, Sodium and Chloride are common substances that require the use of protein channels or carrier proteins.