Animal Reproduction AP Big Ideas: #3: Genetics and Information Transfer #2: Complex Processes and Homeostasis #1 Evolution Goals: • Review meiosis & advantages of sexual Reproduction. • Analyze crossing over data and calculate crossover frequency. • Explain the mechanisms of animal reproduction. Meiosis Crossing Over Similar to Mitosis? Homologous chromosomes Sister Chromatids 3 Ways Sexual Reproduction increases variation Crossing Over • Sordaria lab activity – What is an ascospore? – What evidence do ascospores provide for crossing over? – How do you calculate crossover frequency Mendel’s Laws • Law of Segregation • Law of Independent Assortment • Mendel’s observations support the idea that genes are located on chromosomes! Gene & Allele Law of Segregation Autosomes Sex Chromosomes Haploid (n) Diploid (2n) Are X and Y universal? Is XX always female and XY always male? Chromosome modification at the DNA level X-inactivation • Barr body • DNA methylation • Happens during migration of cells in development. Random!!! Lack of segregation… • Aneuploidy Lack of Segregation… • Polyploidy – Plant speciation Mendel’s Law of Independent Assortment Formative Assessment #1 • Two forms of cell division have evolved. Both have similar mechanisms, however they differ in their overall outcome. – Discuss the similarities and differences between the two forms of cell division in terms of chromosome number and arrangement. – One form of cell division is essential to the diversity of living things. Explain multiple ways that this process has dramatically impacted the diversity of life. Formative Assessment #2 • Mendel didn’t really understand chromosomes…he just observed patterns. Explain to Mendel: – How his Law of Segregation leads to balance of chromosomes and how this balance can be upset – How his law of Independent Assortment allows so many possibilities from just one mating!