Anatomy and Physiology I – Test 3 Fall 2014 1. Match the term with the characteristic on the left. (1 pt each) _ I__ Band that is not found in skeletal muscle _K__ Contains intercalated discs _J___ Voluntary muscle _L__ Is found in the walls of the intestine and arteries _F___ “Light” region of muscle – contains only thin myofilaments _D___ Released from synaptic vesicles A. B. C. D. E. F. G. H. I. J. K. L. Epimysium Synaptic cleft Sarcomere Acetylcholine Troponin I band Myosin Fasicle Kenny Rogers band Skeletal muscle Cardiac muscle Smooth muscle _C___ From one Z line to the next Z line _B___ Gap between nerve as muscle at the neuromuscular junction _H___ Bundle of muscle fibers _E___ Thin myofilament regulatory protein that binds to Ca+2 __G__ Contractile protein on the thick myofilament __A__ Connective tissue that surrounds a whole muscle DESCRIBE a “power stroke” as occurs during muscle contraction AND mention the two muscle proteins that are involved AND whether they are found on the thin or thick myofilament. (3 pts) During a power stroke myosin in the thick mylfilament pulls on actin in the thin myofilament, causing the thin and thick bands to overlap 2. 3. Briefly DESCRIBE each of the following (what is it?) AND tell where each is found. BE SPECIFIC! (2 pts each) a. Synchondrosis Joint in which bones are joined by hyaline cartilage; found between 1st rib and manubrium b. Terminal cisternae Ends of the sarcoplasmic reticulum. Found in the triad surrounding the t-tubule c. Tropomyosin Regulatory protein in the thin myofilament that covers the active site on actin and prevents it from binding myosin in the resting state d. Gomphosis Tooth socket in mouth (within the mandible and maxilla) e. Hinge joint Bones join with convex and concave surfaces interacting; elbow and knee 1 f. Perineurium Connective tissue surrounding a nerve fasicle g. Origin of a muscle The end of a muscle (less mobile) h. Muscle fascicle Bundle of muscle fibers within a skeletal muscle i. Endomysium Connective tissue that surrounds a muscle fiber j. Symphysis Joint in which bones are united by fibrocartilage pad; pubic symphysis, intervertebral discs k. Suture Joint between skull bones l. T-tubule Infolding of the sarcolemma; the central part of the triad m. Syndesmosis Joint in which bones are united through fibrous connective tissue; between ulna and radiues n. Ball-and-socket joint Joint in which rounded, globular head fits into a cup-shaped cavity; between head of humerus and glenoid cavity o. Saddle joint Both interacting bone surfaces contain a concave and a convex region; trapezius and thumb metacarpal p. Aponeurosis Dense regular connective tissue sheet between muscles; lumbar region 4. a. Name all proteins in thick myofilaments AND their function(s) in muscle contraction. (4 pts) Myosin – contractile protein that binds actin and pulls the thin myofilament over the thick b. Name all in thin myofilaments AND their function(s) in muscle contraction. Actin – contractile protein that binds myosin at its active site Tropomyosin – in resting state, blocks active site to prevent actin-myosin binding. During contraction, it moves, uncovering the active site Troponin – after binding Ca+2, it changes shape, forcing troponin to uncover the active site on actin 5. Name and BRIEFLY DESCRIBE THREE functions of skeletal muscle. (3 pts) Look in the notes 6. Name and briefly DESCRIBE the FOUR GENERAL CHARACTERISTICS of muscle? (4 pts) Look in the notes 2 7. Briefly describe the FUNCTION of each during muscle contraction: (1 pt each) a. Sarcoplasmic reticulum Releases Ca+2 b. Myoglobin Stores O2 within the muscle for later use in aerobic respiration, providing ATP as an energy source c. Recovery stroke Extends myosin head to allow it to bind another region of actin d. Ca+2 Binds to troponin, inducing it to change shape e. Na+ Enters the muscle fiber during depolarization f. Acetylcholine Neurotransmitter from the axon that binds to its receptor on the motor end plate; carries a chemical signal across the synaptic cleft g. Junctional folds Infoldings of the sarcolemma that increase its surface area, allowing more ACh to bind to its receptor h. Synaptic bulb End of the motor axon that releases ACh 8. What is the name for the dense regular connective tissue that attaches to muscle to bones? One example attaches the gastrocnemius to the calcaneus (1 pt) Tendon 9. Bones and muscles a. Describe depolarization (include in your answer the ion that is involved and whether it enters of leaves the cell) (1 pt) Na+2 enters the cell b. Describe repolarization (include in your answer the ion that is involved and whether it enters of leaves the cell) (1 pt) K+ leaves the cell What triggers a wave of depolarization along the muscle’s plasma membrane? Name the CHEMICAL that travels across the gap between nerve and muscle AND the molecule on the motor end plate to which it binds (2 pts) When the axon releases ACh, it travels across the synaptic cleft to bind the AChR on the motor end plate. The AChR is a chemically-gated ion channel that permits Na+ to enter the cell and begin depolarization c. d. Name the type of fracture involving distal ends of the ulna and radius that is associated with osteoporosis (1 pt) Colles fracture e. Describe a communuted fracture (1 pt) Bone shatters into several pieces 3 f. Describe an epiphyseal fracture. What SPECIFIC population is more prone to getting this type of fracture? Why is this so? (3 pts) Break at the epiphyseal plate, often in people who are still growing in height since this area is still the softer cartilage at that time 10. BRIEFLY describe AND give an EXAMPLE of the following types of movements: (2 pts each) a. Pronation Turning an anterior surface downwards; turning the hand so that the palm in facing down b. Adduction Moving a part towards the midline; moving the arm towards one’s side c. Rotation Piviting around a point; turning one’s head from side to side d. Plantar flexion Pointing the toes downwards e. Flexion Decreasing the angle between 2 parts; bending one’s arm 11. Are the following characteristics of smooth muscle, skeletal muscle, cardiac muscle, or none of these: LIST ALL CORRECT ANSWERS (1/2 pt each) a. Involuntary Cardiac and smooth b. Lacks striations Smooth c. Cardiac Found in the heart d. Has many nuclei e. Includes the soleus f. Allows a person to move food along the digestive tract Skeletal Skeletal Smooth 12. DESCRIBE a sphincter AND give an example of TWO sphincters. What is the FUNCTION of the TWO sphincters that you named? BE SPECFIC!!! a. A sphincter is …… (1 pt) A ring-like muscle surrounding an opening that controls passage of material through the opening b. Sphincter #1 and its function (2 pts) Cardiac sphincter (bottom of esophagus); prevents stomach contents from moving back into esophagus c. Sphincter #1 and its function (2 pts) Rectal sphincter; allows the release of feces 4 13. DRAW a figure of a microscopic view of muscle on it LABEL the following: (1/2 pt each) a. Thin myofilament d. Area that contains actin b. Sarcomere e. Z line c. A band f. Thick myofilament d. I band g. Area that contains myosin See Lecture 11 notes, bottom of page 8 14. Name each of the TWO SPECIFIC types of movement: (1 pt each) Flexion Plantar flexion Bonuses: 1. What is one symptom of multiple myeloma? Bones break unusually easily, such as when one coughes or while walking 2. Name the muscle and bone attached to the Achilles tendon. Gastocnemius and soleus attached to the calcaneous 3. WWI In what war did Kaiser Wilhelm rule Germany? 5