Fall 2012
Organic Chemistry Lab
CHML211
Lab Schedule, Course Policies,
and Safety Information
Prerequisite/Required Materials
PREREQUISITE: Grade of “C” or better in CHM102!
REQUIRED TEXTS/SUPPLIES:
1. LAB MANUAL:
–
Organic Chemistry: Chemistry 211-212 Laboratory
Manual Fall 2010 Edition—previous editions are
unacceptable
2. LAB NOTEBOOK:
–
Organic Chemistry Laboratory Notebook
3. SAFETY GLASSES/GOGGLES:
–
Can be glasses or goggles, as long as they form a
complete seal around eyes!
Course Website
• https://learn.uncw.edu/webapps/login/
Lab Schedule
Exp. #
***
1
4
6
7
3
5
8
2
10
9*
11
12
Experiment Title
Introduction to Lab: Policies, Safety, Report Formatting
Structure, Intermolecular Forces, and Solubility
TLC and HPLC Analysis of Nitroanilines
Extraction of Analgesics
Recrystallization, Melting Point, and HPLC Analysis of Analgesics
Stereochemistry and Molecular Modeling of Cycloalkanes
Quiz 1(Exp. 1, 4, 6, 7)
Column Chromatographic Separation of Nitroanilines
Bromination of Stilbene—Green Synthesis
Distillation and Gas Chromatography of Alkanes
Quiz 2 (Exp. 3, 5, 8)
Acid-Catalyzed Dehydration of an Alcohol with Rearrangement
Stereochemistry: Enantiomers and Diastereomers
Conversion of an Alcohol to an Alkyl Halide with Rearrangement
Base-Promoted Elimination of HBr from an Alkyl Halide Lab Checkout
Quiz 3 (Exp. 2, 9, 10, 11, 12)
Actual
dates
depend on
lab day.
Please see
your
syllabus for
specific
dates.
Attendance Policy
• All labs are mandatory.
• No make-up labs for any reason.
• Missed lab = zero (regardless of reason).
• Missing 3+ labs = F for course.
• Athletic events are NOT excused absences.
Grading
• Lab is graded separately than lecture!
– Quizzes (45%)
– Final Lab Reports (55%)
• Course Grading:
– A = 90-100, B = 80-89, C = 70-79, D = 60-69, F = 59 and below.
– Plus (+) or minus (-) grades may be awarded at the discretion
of the instructor.
Lab Quizzes
• 3 lab quizzes , 3-5 experiments on each.
• Full experiment after all quizzes! Plan on staying for
the entire lab period!
• Make up quizzes will only be allowed for excused
absences.
– To have a quiz absence excused, the student must:
• Email before beginning of lab
• Bring doctor’s note
Final Lab Reports
• All lab assignments will be available on the course
website.
• Final Lab Reports consist of:
–
–
–
–
Pre-Lab Assignments (20 pts)
In-Lab Assignments (20 pts)
Post-Lab Assignments (50 pts)
Lab Technique/Preparation (10 pts)
• Due dates announced by instructor.
• Late reports = 5% penalty per day
– Once lab reports are returned to students graded, NO
MORE WILL BE ACCEPTED!
Lab Technique
• You are responsible for your own safety!
– Be prepared and familiar with safety hazards!
– Wear proper shoes and eye protection!
– Common sense and thinking are REQUIRED.
• You are responsible for cleaning up after
yourself!
– YOU. Not your lab instructor. If we clean, you pay.
Personal Electronics
• Cell phone use WILL NOT BE tolerated.
– Turn ON SILENT OR VIBRATE before lab and PUT IT
AWAY!
– YOURS rings = you leave = ZERO
– Cannot use phone as calculator during quizzes!
• Laptops and desktop computers use is allowed for
lab related activities ONLY.
• Ipod use is not acceptable in lab!
Other Issues
• Please refer to the online syllabus for
information regarding:
–
–
–
–
Learning Outcomes
Academic Integrity
Students with Disabilities
Violence and Harassment
Safety in the Organic Lab
• Follow instructions at all times!
• Act responsibly at all times!
• No food or drinks on lab benches!
• Dress appropriately for lab!
• Come prepared! Know what you are going to do,
and what the hazards are!
• Report all accidents to the instructor, no matter
how small.
Acceptable Clothing for Lab…
• DO wear
– Goggles/safety glasses
– Closed-toe shoes
– Tie back long hair
• DON’T wear
– Sandals/flip-flops
– Jewelry
– Loose or baggy clothing
Lab Safety Equipment
Safety Shower
Eyewash
Safety Goggles/glasses
Lab Safety Equipment
Fire Extinguisher
Fume Hood
Accidents and Injuries
• Report ALL injuries to lab instructor IMMEDIATELY,
no matter how minor.
• Be aware of hazards associated with each chemical
and technique you will use in the experiment!
• Complete an Injury Report Form.
First Aid
• Eye accidents: Wash eyes in stream of water using
eyewash station for 15 minutes!
• Chemical burns: Immediately flush the affected area with
a large amount of water in the sink! Use safety shower if
necessary!
• Thermal burns: Determine the type and extent of the
burn. Take appropriate action.
– 1st degree: red skin, no blisters.
• Immerse in cold water/apply ice.
– 2nd degree: blisters.
• Immerse in cold water, then apply clean gauze.
– 3rd degree: broken skin, tissue damage.
• Cover with clean gauze. Visit the Health Center.
First Aid
• Bleeding, cuts, and abrasions:
– Clean wound with soap and warm water.
– Apply pressure with clean gauze pad until bleeding stops.
– Cover wound with bandage or clean gauze pad and secure.
• Poisoning:
– If, after contact with, inhalation of, or accidental ingestion of
a chemical, you experience discoloration of the lips, a
burning sensation in the throat, stomach cramps, nausea
and vomiting, or confusion, seek treatment IMMEDIATELY
for chemical poisoning!
UNCW Safety Contract
• READ Laboratory Rules and Guidelines (p. vii)
CAREFULLY!
• READ, SIGN, AND SUBMIT safety contract (p. xi) to
instructor!
Waste Disposal
• Waste disposal procedures are at end of the
procedure for each experiment.
• If you do not know which waste goes where,
ASK!
• NOTHING DOWN THE SINK!