PSY 101 – Dr. V Chapter 2 Lecture Notes Module 4 – Neural and Hormonal Systems Overview of Nervous System • Nervous System - _______________________________________________________________ ______________________________________________________________________________ • Neuroscience – deals with the structure and function of the brain and the neurons, nerves, and nervous tissue that form the nervous system. • Relationship to behavior and learning. Structure of the Neuron • Neurons - ______________________________________________________________________ ______________________________________________________________________________ • Parts of a Neuron • _________________ - branch-like structures that receive messages from other neurons. • __________ - the cell body of the neuron, responsible for maintaining the life of the cell. • _________ - long tube-like structure that carries the neural message to other cells. Other Types of Brain Cells • Glial cells - grey fatty cells that: • ________________________________________________________________________ • ________________________________________________________________________ • produce myelin to coat axons, • Myelin Sheath - ____________________________________________________ _________________________________________________________________ _________________________________________________________________ • Generated by a Schwann Cell • clean up waste products and dead neurons. • Note: Neurons only makeup 10% of cells in the brain; the remaining 90% is glial Neurons in the Body • Nerves – _______________________________________________________________________ • Neurilemma – Schwann’s membrane. • _________________________________________________________________ _________________________________________________________________ • Most axons of the neurons in the brain and spinal cord do not usually have this coating, thus, more likely to be permanently damaged. 1 PSY 101 – Dr. V • _______________________ – disease that damages the myelin sheath (i.e., demyelination), which leads to a loss of function in those damaged cells. Neuron Generating the Message: Neural Impulse • Ions – charged particles. • Inside neuron – __________________________ • Outside neuron – ___________________________ • Resting potential – the state of the neuron when not firing a neural impulse. • ________________ – Each neuron receives excitatory and inhibitory signals from many neurons. When the excitatory signals minus the inhibitory signals exceed a minimum intensity (threshold) the neuron fires an action potential • _______________________ - the release of the neural impulse consisting of a reversal of the electrical charge within the axon. • • Allows positive sodium ions to enter the cell. All-or-none – ___________________________________________________________________ ______________________________________________________________________________ • Difference between strong stimulation and weak stimulation? – strong message results in the neuron firing more quickly, and it will also cause more neurons to fire. • ________________________ – neuron is incapable of repeating (i.e., firing) until returns to resting potential (very brief – often milliseconds) • Return to resting potential. 2 PSY 101 – Dr. V Action Potential Sending the Message to Other Cells • Axon terminals - branches at the end of the axon. • Synaptic knob (or terminal button) – rounded areas on the end of axon terminals. • Synaptic vesicles - __________________________________________________ _________________________________________________________________ • ___________________________- chemical found in the synaptic vesicles which, when released, has an effect on the next cell. • Synapse/synaptic gap - microscopic fluid-filled space between the rounded areas on the end of the axon terminals of one cell and the dendrites or surface of the next cell. • _____________________ - holes in the surface of the dendrites or certain cells of the muscles and glands, which are shaped to fit only certain neurotransmitters. 3 PSY 101 – Dr. V 4 Cleaning up the Synapse • ______________ - process by which neurotransmitters are taken back into the synaptic vesicles; applies the “breaks” on neurotransmitter action. • Enzyme - a complex protein that is manufactured by cells. • e.g., one type specifically breaks up acetylcholine because muscle activity needs to happen rapidly, so reuptake would be too slow. How Neurotransmitters Influence Us Serotonin pathways are involved with _______________________________________________ _____________ pathways are involved with diseases such as schizophrenia and Parkinson’s disease. ________________ – produce good feelings (e.g., “runner’s high”) o explains painkilling effects of acupuncture o explains indifference to pain when severely injured o opiates ______________ _____________ when flooded with opiate drugs, the brain stops producing own natural opiates when drug is withdrawn, deprivation of opiates causes great discomfort (i.e., withdrawal) PSY 101 – Dr. V 5 Neuron Communication • Neurons must be turned ON and OFF. • Excitatory neurotransmitter - neurotransmitter that causes the receiving cell ________ • Inhibitory neurotransmitter - neurotransmitter that causes the receiving cell ___________ • Chemical substances can affect neuronal communication: Agonists & Antagonists Lock & Key Mechanism – neurotransmitters bind to the receptors of the receiving neuron in a key-lock mechanism. o o Agonist – ________________________________________________________________ Some opiate drugs amplify normal sensations of arousal and pleasure (i.e., “high”) Black widow spider venom – _____________________________________ = violent muscle contractions, convulsions, possible death Antagonist – _____________________________________________________________ ________ – causes paralysis by blocking ACh release; can come from improperly canned food __________________ – smoothes wrinkles by paralyzing the underlying facial muscles Some antagonists will occupy receptor sites and block its effect; similar to the natural neurotransmitter, but not similar enough to stimulate the receptor __________ – a poison that can be applied to hunting-dart tips o Occupies and blocks ACh receptor sites, which does not allow the neurotransmitter to affect the muscles = paralysis PSY 101 – Dr. V The Nervous System Central Nervous System • Central nervous system (CNS) - ____________________________________________________ ______________________________________________________________________________ • Spinal cord - a long bundle of neurons that carries messages to and from the body to the brain that is responsible for very fast, lifesaving reflexes. The Reflex Arc: Three Types of Neurons • Sensory neuron - ________________________________________________________________ ______________________________________________________________________________ • • Motor neuron - _________________________________________________________________ ______________________________________________________________________________ • • Also called _____________________ Also called _____________________ __________________ - a neuron found in the center of the spinal cord that receives information from the sensory neurons and sends commands to the muscles through the motor neurons. • This _________________ skips going to the brain – like a shortcut • Interneurons also make up the bulk of the neurons in the brain. 6 PSY 101 – Dr. V The Spinal Cord & Reflexes Peripheral Nervous System • Peripheral nervous system (PNS) - __________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ • Somatic nervous system • Autonomic nervous system Somatic Nervous System • Soma = body. • Somatic nervous system - ________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ • Sensory pathway - nerves coming from the sensory organs to the CNS consisting of sensory neurons. • Motor pathway - nerves coming from the CNS to the voluntary muscles, consisting of motor neurons – i.e., skeletal muscles Autonomic Nervous System • Autonomic nervous system (ANS) - division of the PNS consisting of nerves that control all of the ______________________ muscles, organs, and glands sensory pathway nerves coming from the sensory organs to the CNS consisting of sensory neurons. • ____________________________________________ - part of the ANS that is responsible for reacting to stressful events and bodily arousal. • ____________________________________________ - part of the ANS that restores the body to normal functioning after arousal and is responsible for the day-to-day functioning of the organs and glands. 7 PSY 101 – Dr. V The Endocrine Glands • Endocrine glands - glands that secrete chemicals called hormones directly into the bloodstream. • • Hormones - chemicals released into the bloodstream by endocrine glands. _____________________ - gland located in the brain that secretes human growth hormone and influences all other hormone-secreting glands (also known as the ______________________). • Remember: influenced by the hypothalamus • Pineal gland - endocrine gland located near the base of the cerebrum that secretes melatonin, which regulates _________________________________________________________________ • Thyroid gland - endocrine gland found in the neck that secretes thyroxin, which regulates ______________________________________________________________________________ • ______________- endocrine gland that controls the levels of sugar in the blood by secreting insulin and glucagons. • • • Too little insulin = _________________ • Too much insulin = ____________________ (low blood sugar) – feel hungry all the time Gonads - the sex glands that secrete hormones that regulate sexual development and behavior as well as reproduction. • Ovaries - the female gonads. • Testes - the male gonads. ______________________ - endocrine glands located on top of each kidney that secrete over 30 different hormones to deal with stress, regulate salt intake, and provide a secondary source of sex hormones affecting the sexual changes that occur during adolescence. • _______________ – one of the most “important” adrenal hormones • Released when the body experiences __________________________________ 8