CHEMISTRY OF LIFE A. Inorganic compounds—without carbon 1. Water (H2O)—most important inorganic compound a. excellent solvent (universal)—because it is polar covalent b. high heat capacity 2. Acids and bases—measured on pH scale. Fluctuations in pH can change the rate and nature of internal chemical reactions. a. Acid—strong acids, pH near 0. Characterized by an abundance of H30+ (hydronium) ions. b. Base—strong bases pH near 14. Characterized by an abundance of OH- (hydroxide) ions. B. Organic compounds—compounds containing carbon. Most composed of basic units that repeat. These units are called monomers. Polymers are formed from the condensation of many monomers and are called macromolecules. 1. Carbohydrates—contain carbon, hydrogen, and oxygen (have ratio of 2 hydrogen atoms and 1 oxygen atom per carbon atom). The body’s main source of energy and used as structural compounds. a. Monosaccharides—simple sugars; monomers of carbohydrates. Common monosaccharides include glucose, fructose, and galactose. All have the simple formula of C6H12O6. b. Disaccharides—double sugars. Formed from the condensation of two monosaccharides. Examples include: (1) (2) (3) c. Maltose (malt sugar)—glucose + glucose Lactose (milk sugar)—glucose + galactose Sucrose (table sugar)—glucose + fructose Polysaccharides—complex sugars. Composed of long chains of monosaccharides. (1) Starch—plant energy storage, polymer of glucose. Forms single line chains of molecules. (2) Glycogen—animal energy storage, polymer of glucose. Forms branching chains of molecules. (3) Cellulose—indigestible, dietary fiber for animals. Forms the cell wall of many plant cells. (4) Chitin—makes up the exoskeleton of arthropods and cell walls of fungi. 2. Lipids—also contain carbon, hydrogen, and oxygen, but in a different ratio than carbohydrates. Include fats, oils, waxes, and steroids (fat based hormones). More complex than carbohydrates. Triglycerides (found in fats and oils) are made of glycerol + three fatty acids. More energy per gram than carbohydrates. Used for energy storage, cell membranes, and in the nervous system. 3. Proteins—basic building blocks of tissues; monomers of proteins. Contain carbon, hydrogen, and oxygen as well as nitrogen and sulfur. Made of monomers called amino acids. Used structurally and as biological catalysts called enzymes. a. Amino acids—monomers of proteins; made of an organic acid or carboxyl group (COOH), amino group (NH2), single carbon atom attached to hydrogen, and an R-group. Each of the twenty (20) different amino acid differs in the R-group. b. Dipeptides—two amino acids joined by peptide bonds. c. Polypeptides—three or more amino acids joined by peptide bonds. All proteins consist of these. The sequence of amino acids determines the type of protein. Shapes of protein molecules vary with the sequence of the amino acids and determine their properties. Enzymes—proteins that act as biological catalysts. a. Names of many enzymes end in “ase”. Examples include sucrase (works on sucrose) and maltase (works on maltose). b. Each enzyme works on a specific substrate. c. They lower the amount of activation energy needed to start reaction. d. Vitamins may act as co-enzymes. 5. Nucleic acids—carry instructions for cellular activity. a. DNA (deoxyribonucleic acid)—records instructions and transmits them from generation to generation. Found primarily in the nucleus of the cell. b. RNA (ribonucleic acid)—reads and carries out instructions. Found in nucleus and cytoplasm of the cell. Both are made of complex monomers called nucleotides.