Назва наукового напрямку (модуля):
Семестр: 4
Module 2. Carboxylic acids, heterocyclic and natural compounds.
O
H2C
CH
C
1. What are the products of reaction
A. 2-bromopropanoic acid
B. 2-bromopropanoic acid and HBr
C. 2-bromopropanoic acid and water
D. *3-bromopropanoic acid
E. 3-bromopropanoic acid and HBr
+ HBr
?
OH
O
C
OH
CH2
CH2
OH
C
2. Choose the right name of carboxylic acid
A. oxalic acid
B. mallonic acid
C. adipic acid
D. formic acid
E. *succinic acid
O
O
CH2 CH
C
+ Br2
3. What are the products of reaction
A. 2,3-dibromopropanoic acid and H2O
B. *2,3-dibromopropanoic acid
C. bromoanhydride of propanoic acid + H2O + HBr
D. 3-bromopropanoic acid and HBr
E. 2-bromopropanoic acid and HBr
?
OH
O
CH
CH
C
OH
4. Choose the right name of carboxylic acid
A. *cinnamic acid
B. succinic acid
C. formic acid
D. isovaleric acid
E. valeric acid
5. Which of the following reagent can be used to form anhydrides?
A.
B.
C.
D. .*
E.
6. What are the products of the reaction between phthalic anhydride and primary amines?
A. .*
B.
C.
D.
E.
7. What is the identity of the intermediate (A) and the end-product (B) in the
following scheme?
A.
B.
C. *
D.
E.
8. Choose the correct range of acidity increase for the following compounds.
A. a, c, b
B. c, a, b
C. c, b, a
D. b, a, c
E. *a, b, c
9. Choose the correct range of acidity increase for the following compounds.
A. a, c, b
B. c, a, b
C. *c, b, a
D. b, a, c
E. a, b, c
10. Choose the correct range of acidity increase for the following compounds.
A. *b;c;a
B. c;a;b
C. c, b, a
D. b;a;c
E. a;b;c
11. Which of the following compounds will interact with carboxylic acids
to get anhydrides?
A.
B.
C.
D. *
E.
12. Which intermediate and the end-product are formed in the reaction of ammonia with acetic
acid?
A.
B.
C.
D. *
E.
13. Choose the correct range of acidity increase for the following compounds.
A. a, c, b
B. c, a, b
C. *c, b, a
D. b, a, c
E. a, b, c
14. Choose the correct range of acidity increase for the following compounds.
A. a, c, b
B. c, a, b
C. c, b, a
D. *b, a, c
E. a, b, c
15. Choose the correct range of acidity increase for the following compounds.
A. a, c, b
B. c, a, b
C. c, b, a
D. b, a, c
E. *a, b, c
16. Choose the correct range of acidity increase for the following compounds.
A. *a, c, b
B. c, a, b
C. c, b, a
D. b, a, c
E. a, b, c
17. Which of the following compound will interact with benzoic acid?
A.
B.
C.
D. *
E.
18. Which of the following reactions leads to the formation of acetophenone?
A.
B.
C.
D. *
E.
19. Compound with characteristic smell, which changes coloration of litmus paper, forms gas after
the adding of zinc and gives „silver mirror” reaction, is:
A. НС(О)Н
B. С6Н5ОН
C. *НСООН
D. СН3С(О)Н
E. СН3СООН
20. At the interaction of carboxylic acids with alcohols at the heating in the presence of H2SO4
form:
A. Aldehydes
B. Ethers
C. Phenols
D. Ketones
E. *Esters
21. Potassium stearate – liquid soap, its formula:
A. C17H33COOK
B. *C17H35COOK
C. C17H31COOK
D. C17H29COOK
E. C3H7COOК
22. Choose formula of unsaturated carboxylic acid:
A. *C17H33COOH
B. C17H35COOH
C. C3H7COOH
D. C10H21COOH
E. C12H23COOH
23. Which of the following carboxylic acids has properties of aldehyde and acid?
A. CH2Cl – COOH
B. CH3COOH
C. *HCOOH
D. CCl3 – COOH
E. C3H7COOH
24. Which of the following compounds is a product of propanoic acid chlorination?
A. CH3 – CH2 – COCl
B. *CH3 – CHCl – COOH
C. CH2Cl – CH2 – COOH
D. CH3 – CH2 – COOCl
E. C3H7COOH
25. Choose the strongest carboxylic acid:
A. CH3COOH.
B. CH3CH2COOH.
C. CH2Cl – COOH.
D. *CCl3 – COOH.
E. CH3CH2CH2COOH
26. In the reaction CH3CH2COOH + NaHCO3 the following gaseous product forms:
A. CH4
B. CO
C. *CO2
D. C2H6
E. C2H4
27. Among of the following compounds specify formula of chloroacetic acid:
A. CH3COOH
B. *CH2(Сl)COOH
C. CH2(NH2)COOH
D. CH2(CH3)COOH
E. CСl3COOH
28. Determine reaction that cases propanoic acid formation:
A. CH3-C(O)H + [O] - CH3-COOH
B. H-C(O)H + [O] - H-COOH
C. CH3-CH2-CH2-C(O)H + [O] - CH3-CH2-CH2-COOH
D. *CH3-CH2-C(O)H + [O] - CH3-CH2-COOH
E. CH3-CH2-CH2-CH2-C(O)H + [O] - CH3-CH2-CH2-CH2-COOH
29. Soap belongs to the following class of compounds:
A. Alcohols
B. Carboxylic acids
C. Esters
D. *Salts
E. Phenols
30. Ethyl ester of acetic acid can be obtained by the following reaction:
A. CH3-CH2-OH + CH3-CH2-OH B. CH3-COOH + CH3-COOH C. *CH3-COOH + CH3-CH2-OH D. CH3 COOH + CH3-OH E. CH3-COOH + Na2CO3
31. Specify compound, which with acetic acid will not form salts:
A. *CH3-COOH + C2H5OHO
B. CH3-COOH + Na2CO3
C. CH3-COOH + Na
D. CH3-COOH + Mg
E. CH3-COOH + CH3-COOH
32. Lead (ІІ) acetate has the following formula:
A. Pb(OH)CH3COO
B. Pb(CH3COO)4
C. *Pb(CH3COO)2
D. Pb(CH3COO)3
E. Pb(CH3COO)5
33. In the reaction CH3-COOH + NaOH = the following compounds form:
A. *CH3-COONa + H2O
B. CH3-COONa + H2
C. CH3-COONa + O2
D. 2CH3-COONa + H2O2
E. 3CH3-COONa + H2O2
34. At the interaction of acetic acid and magnesium (CH3?COOH + Mg) gas … evaporates:
A. CO2
B. CO
C. *H2
D. H2O(water steam)
E. С2Н2
35. Ion CH3-COO- has the following name:
A. Formiate
B. Carbonate
C. Hydrocarbonate
D. *Acetate
E. Dihydrocarbonate
36.
125. Specify compound, which will not interact with acetic acid:
A. Nа
B. NaOH
C. Na2O
D. *CO2
E. Mg
37. Specify compound, which will interact with carboxylic acids:
A. *NaOH
B. CO2
C. H2O
D. NaCl
E. KBr
38. Litmus paints solution of acetic acid in ... color:
A. Green
B. *Red
C. Blue
D. Colorless
E. Purple
39. For the detection of acetic acid can be used:
A. *Indicator and sodium hydrogen carbonate
B. Bromine water
C. Freshly precipitated Cu(OH)2
D. Ammonium solution of Ag2O
E. Lime water
40. In the esterification reaction ОН-group eliminates (for the water formation) from the molecule
of:
A. Alcohol
B. Ketone
C. Aldehyde
D. *Acid
E. Phenol
41. Method of formic acid obtaining:
A. Ethane oxidation
B. *Methane oxidation
C. Phenol oxidation
D. Reaction of СН3ОН with СО
E. Ethylene oxidation
42. For the acetic acid obtaining, as primer compound is used:
A. HCOON
B. CH3OH
C. C4H10
D. C3H7OH
E. *С2Н2
43. Glycerin and stearic acid can be obtained by the reaction of:
A. Etherification
B. Hydrolysis of carbohydrates
C. Esterification
D. *Hydrolysis of fat
E. Hydratation of carbohydrates
44. Glycerin and palmitic acid can be obtained by the reaction of:
A. Cracking of petroleum
B. Esterification
C. *Hydrolysis of fat
D. Hydrolysis of carbohydrates
E. Hydratation of carbohydrates
45. At the hydrolysis of solid fats the following acid forms:
A. Glycerin
B. Formic acid
C. Ethylene glycol
D. Acetic acid
E. *Stearic acid
46. Which of the following reaction conducts with hydrogen evaporation?
A. *СН3 – СООН + Са
B. СН3 – СООН + NaOH
C. СН3 – СООН + СаО
D. СН3 – СООН + СН3OH O
E. СН3 – СООН + Са(ОН)2
47. Choose the reaction of Carbon (ІV) oxide formation:
A. СН3 – СООН + NaOH
B. СН3 – СООН + Zn
C. *СН3 – СООН + Na2СO3
D. СН3 – СООН + СаО
E. СН3 – СООН + Са(ОН)2
48. Which of the following properties are common for methanoic and hydrochloric acid?
A. Interaction with alkalis and ammonium solution of Ag2O
B. *Interaction with metals and alkalis
C. Action of conc. Н2SO4.
D. Decomposition at the heating
E. Interaction with fuxin sulfite acid
49. In which of the following rows all compounds will react with formic acid?
A. СН3С(О)Н; СН3 – ОН; СН3СООН
B. *С2Н5ОН; Ag2O(ammonium solution); Мg(met.)
C. Сu(OH)2; Na2CO3; C3H8
D. CH4; NaOH; CH3Cl
E. Сu(OH)2; CH4; NaOH; CH3Cl
50. Functional group -COOH has the name:
A. Aldehyde-group
B. Hydroxyl group
C. *Carboxyl group
D. Keto-group
E. Phenol hydroxyl
51. Saturated monobasic carboxylic acids have the following general formula:
A. R-OH
B. R-C(O)H
C. R-CH2-OH
D. *R-COOH
E. R-C(O)OR
52. Among of the following compounds specify formula of carboxylic acid:
A. *CH3-COOH
B. CH3-OH
C. CH3-CH2-OH
D. CH3-COH
E. CH3-C(O)OCH3
53. Methanoic acid has the following formula:
A. CH3-COOH
B. CH3-OH
C. CH3-CH2-OH
D. *H-COOH
E. CH3-COH
54. Choose chemical formula of valeric acid:
A. CH3COOH
B. CH3CH2COOH
C. CH3CH2CH2COOH
D. *CH3CH2CH2CH2COOH
E. CH3CH2CH2CH2CH2CH2COOH
55. Choose chemical formula of butyric acid:
A. CH3COOH
B. CH3CH2COOH
C. *C3CH2CH2COOH
D. CH3CH2CH2CH2COOH
E. CH3CH2CH2CH2CH2CH2COOH
56. The strongest monobasic saturated carboxylic acid is the following one:
A. *HCOOH
B. CH3COOH
C. CH3CH2COOH
D. CH3CH2CH2COOH
E. CH3CH2CH2CH2CH2CH2COOH
57. To distinguish formic acid from acetic acid the following reagent can be used:
A. NH3
B. NaOH
C. *[Ag(NH3)2]OH
D. NaHCO3
E. Ca(OH)2
58. Salts of methanoic acid are called:
A. Acetates
B. Carbonates
C. Lactates
D. Propionates
E. *Formiates
59. Formic acid, except acidic properties, also has properties of:
A. Alcohols
B. Ketones
C. *Aldehydes
D. Amines
E. Phenols
60. Product of the formic acid dehydration is:
A. СО2
B. *СО
C. СН4
D. С2Н2
E. С2Н4
61. Organic product of the interaction of carboxylic acid with alcohol is:
A. *Ester
B. Ether
C. Ketone
D. Aldehyde
E. Anhydride
62. At the total reduction of carboxylic acids are formed:
A. *Alcohols
B. Aldehydes
C. Ketones
D. Esters
E. Ethers
63. Choose the formula of ammonium acetate:
A. NH4Cl
B. *CH3COONH4
C. HCOONH4
D. CH3COON
E. СН3СН2СООNH4
64. What compound has the biggest acidic properties?
A. Ethanol
B. Glycerin
C. Acetic acid
D. *Formic acid
E. Phenol
65. Gaseous product of the “silver mirror” reaction by the participant of methanoic acid is:
A. CH4
B. H2
C. CO
D. *CO2
E. С2Н2
66. Gaseous product of the methanoic acid dehydration is:
A. CH4
B. H2
C. *CO
D. CO2
E. С2Н2
67. Compound НСООН gives reactions, which are characteristic for:
A. Organic acids and alcohols
B. *Organic acids and aldehydes
C. Alcohols and aldehydes
D. Aldehydes and esters
E. Phenols and aldehydes
68. How many asymmetric carbon atoms and possible stereoisomers does tartaric acid have?
A. no asymmetric carbon atoms and it is optically inactive
B. two asymmetric carbon atoms and two stereoisomers
C. *two asymmetric carbon atoms and three stereoisomers
D. two asymmetric carbon atoms and four stereoisomers
E. one asymmetric carbon atom and two stereoisomers
69. How many asymmetric carbon atoms and possible stereoisomers does malic acid have?
A. no asymmetric carbon atoms and it is optically inactive
B. two asymmetric carbon atoms and four stereoisomers
C. *one asymmetric carbon atom and two stereoisomers
D. one asymmetric carbon atom and one stereoisomer
E. two asymmetric carbon atoms and two stereoisomers
70. Which of the following reagent interact with carboxylic-group of
α-bromopropanoic acid?
A.
B.
C.
D. *
E.
71. How many asymmetric carbon atoms and possible stereoisomers does lactic acid have?
A. no asymmetric carbon atoms and it is optically inactive
B. two asymmetric carbon atoms and four stereoisomers
C. two asymmetric carbon atoms and two stereoisomers
D. *one asymmetric carbon atom and two stereoisomers
E. one asymmetric carbon atom and one stereoisomer
72. Which hydroxyacid does decompose at treatment with conc. H2SO4 according to the following
scheme?
A.
B.
C.
D.
E. *
73. Which hydroxyacid decomposes at treatment with conc. H2SO4 according to the following
scheme?
A.
B.
C.
D.
E. *
74. Which hydroxyacid decomposes at treatment with conc. H2SO4 according to the following
scheme?
A.
B.
C.
D.
E. *
75. What is the product of reaction between pyruvic acid and hydroxylamine?
A.
B.
C.
D.
E. *
76. What products are formed when diethylacetoacetic ester is treated with diluted
mineral acid?
A.
B.
C.
D.
E. *
77. What products are formed when methylpropylacetoacetic ester is treated with concentrated
solution of alkali?
A.
B.
C.
D. *
E.
78. What product is formed when γ -hydroxyvaleric acid is heated?
A.
B.
C. *
D.
E.
F.
79. What product is formed when β -hydroxybutyric acid is heated?
A.
B.
C. *
D.
E.
80. Choose the correct range of acidity increase for the following compounds.
A. d > b > a > c
B. d < b < a < c
C. c < b < a < d
D. b < a < c < d
E. *c < d < b < a
81. Which is the product of salicylic acid nitration?
A.
B.
C.
D.
E. *
82. How many asymmetric carbon atoms and possible stereoisomers does α-hydroxybutyric acid
have?
A. no asymmetric carbon atoms and it is optically inactive
B. two asymmetric carbon atoms and one stereoisomer
C. one asymmetric carbon atom and one stereoisomer
D. two asymmetric carbon atoms and two stereoisomers
E. *one asymmetric carbon atom and two stereoisomers
83. Malic acid is:
A. monobasic biatomic acid
B. tribasic biatomic acid
C. *dibasic triatomic acid
D. dibasic monoatomic acid
E. tribasic triatomic acid
84. What product is formed when tartaric acid is heated in the presence of KHSO4?
A.
B.
C.
D. *
E.
85. What product is formed when γ-hydroxybutyric acid is heated?
A.
B. *
C.
D.
E.
86. What is the identity of the reagent ¬¡ and intermediate B in the following scheme?
A.
B. *
C.
D.
E.
87. Choose the pair of reagents which can be used to obtain β-hydroxybutyric acid by Reformatsky
reaction.
A.
B. *
C.
D.
E.
88. Choose the correct name of the following compound.
A. oxoketoglutaric acid
B. α-ketopentanedioic acid
C. *β- ketoglutaric acid
D. 2- ketoglutaric acid
E. oxopentanedioic acid
89. Choose the correct name of the following compound.
A. chlorosuccinic acid
B. 3- chlorobutyric acid
C. *3- chlorobutanoic acid
D. α - chloropentanoic acid
E. 3-chloropentanoic acid
90. Which of the following reagent shall react with both functional groups of βchloropropanoic acid?
A.
B.
C.
D.
E. *
91. Citric acid is:
A. monobasic triatomic acid
B. tribasic monoatomic acid
C. *tribasic tetraatomic acid
D. tetrabasic triatomic acid
E. tribasic triatomic acid
92. Trataric acid is:
A. tribasic tetraatomic acid
B. tetrabasic tetraatomic acid
C. tetrabasic biatomic acid
D. *dibasic tetraatomic acid
E. dibasic biatomic acid
93. Which hydroxycarboxylic acid decomposes at treatment with conc. H2SO4
according to the following scheme?
A.
B.
C.
D.
E. *
94. Which way does citric acid decomposes?
A.
B.
C.
D.
E. *
95. What product is formed when α-hydroxypropanoic acid is heated?
A.
B. *
C.
D.
E.
96. What products are formed when acetoacetic ester is treated with concentrated solution of
alkali?
A.
B.
C.
D. *
E.
97. What product is formed when urea is slowly heated?
A.
B.
C. *
D.
E.
98. What products are formed when ethylacetoacetic ester is treated with diluted
mineral acid?
A.
B.
C.
D.
E. *
99. Which is the product of the following reaction?
A. *
B.
C.
D.
E.
100.
What products are formed when methylacetoacetic ester is treated with diluted mineral
acid?
A.
B.
C.
D. *
E.
101.
Which wayα-chlorosuccinic acid could be obtained?
A.
B.
C.
D. *
E.
102.
Which of the following is α - ketoglutaric acid?
A. *
B.
C.
D.
E.
103.
Which of the following compounds is glyoxylic acid?
A.
B.
C.
D. *
E.
104.
Which way α-chloropropanoic acid could be obtained?
A.
B.
C.
D. *
E.
105.
Which of the following is tartaric acid?
A. *
B.
C.
D.
E.
106.
Which of the following reaction lead to formation of pyruvic acid?
A.
B.
C.
D.
107.
E. *
Which of the following is acetylsalicylic acid?
A.
B.
C.
D. *
E.
108.
Which of the following is salicylic acid?
A.
B.
C. *
D.
E.
109.
Which of the following is citric acid?
A.
B.
C.
D. *
E.
110.
Which of the following is oxalacetic acid?
A.
B. *
C.
D.
E.
111.
Which of the following is acetoacetic acid?
A.
B. *
C.
D.
E.
112.
Which of the following compounds is o-hydroxycinnamic acid?
A. *
B.
C.
D.
E.
113.
Which of the following compounds is malic acid?
A.
B.
C. *
D.
E.
114.
Choose the correct name of the following compound.
A.
B.
C.
D.
E.
propylbromoacetic acid
α - bromovaleric acid
2-bromo-3-methylpropanoic acid
*2-bromo-3-methylbutanoic acid
α - bromobutyric acid
115.
Salicylic acid has two acidic centers and therefore forms two rows of salts. What reagent
can be used to form disodium salt of salicylic acid?
A. *NaOH
B. NaНCO3
C. NaCl
D. Na2SO4
E. CH3COONa
116.
α–Hydroxyacids at the heating will form:
A. lactides
B. *lactones
C. saturated α-acids
D. esters with open carbon chain
E. acetoacetic ester
117.
Salicylic acid has two acidic centers and therefore forms two rows of salts. What reagent
can be used to form disodium salt of salicylic acid?
A. *NaOH
B. NaНCO3
C. NaCl
D. Na2SO4
E. CH3COONa
118.
Choose acid, which forms -lactone after the heating?
A. pyruvic
B. glycolic
C. lactic
D. *4-hydroxybutanoic
E. malic
119.
At the adding to the organic compound FeCl3, dark violet color will form. Name this
compound?
A. benzoic acid
B. benzene
C. toluene
D. acetylsalicylic acid
E. *salicylic acid
120.
Galic acid is a part of thiamine. To which class of compounds does this acid belong?
A. alcohol acids
B. *phenoloacids
C. aminoacids
D. aldehyde acids
E. ketoacids
121.
What compound will form at the interaction of lactic acid with excess of SOCl2?
A. 2-chloropropanoic acid
B. chloroanhydride of lactic acid
C. *chloroanhydride of 2-chloropropanoic acid
D. 2-chlorolactic acid
E. 3-chlorolactic acid
122.
What reagent is used for the acetoacetic ester determination?
A. *FeCl3
B. CuSO4
C. Formaldehyde
D. Ethyl alcohol
E. KMO4
123.
Which of the following reagents will react with glyoxylic acid by aldehyde group?
A. Nа
B. NaOH
C. SОCl2
D. *NH2OH
E. NaHCO3
124.
A.
B.
C.
D.
E.
125.
A.
B.
C.
D.
E.
126.
A.
B.
C.
D.
E.
127.
A.
B.
C.
D.
E.
128.
A.
B.
C.
D.
E.
129.
A.
B.
C.
D.
E.
130.
A.
B.
C.
D.
E.
131.
A.
B.
C.
D.
E.
132.
A.
B.
C.
D.
E.
133.
A.
B.
Which of the following reagents will react with glyoxylic acid by aldehyde group?
Nа
NaHCO3
NaOH
SОCl2
*Ag(NH3)2OH
Which of the following reagents will react with glyoxylic acid by aldehyde group?
NaOH
NaHCO3
*HCN
SОCl2
Nа
Which of the following reagents will react with glyoxylic acid by aldehyde group?
NaHCO3
*NH2NH2
NaOH
SОCl2
Nа
Which of the following reagents will react with glyoxylic acid by aldehyde group?
*NH2NHC6H5
NaHCO3
NaOH
SОCl2
Nа
Which of the following reagents will react with glyoxylic acid by aldehyde group?
Nа
NaHCO3
NaOH
SОCl2
*NH2NHC(O)NH2
Which of the following reagents will react with glyoxylic acid by aldehyde group?
NaOH
NaHCO3
*NH2NHC(S)NH2
SОCl2
Nа
Which of the following reagents will react with glyoxylic acid by carboxylic group?
Ag(NH3)2OH
C6H5NHNH2
NH2OH
*NaHCO3
NH2NH2
Which of the following reagents will react with glyoxylic acid by carboxylic group?
Ag(NH3)2OH
*NaOH
NH2OH
C6H5NHNH2
NH2NH2
Which of the following reagents will react with glyoxylic acid by carboxylic group?
*Na2CO3
Ag(NH3)2OH
NH2OH
C6H5NHNH2
NH2NH2
Which of the following reagents will react with glyoxylic acid by carboxylic group?
Ag(NH3)2OH
NH2NH2
134.
135.
136.
137.
138.
139.
140.
141.
142.
C. NH2OH
D. C6H5NHNH2
E. *Na
Which of the following reagents will react with glyoxylic acid by carboxylic group?
A. Ag(NH3)2OH
B. C6H5NHNH2
C. NH2OH
D. *C2H5OH
E. NH2NH2
Which of the following reagents will react with glyoxylic acid by carboxylic group?
A. Ag(NH3)2OH
B. *CH3OH
C. NH2OH
D. C6H5NHNH2
E. NH2NH2
Which of the following reagents will react with acetoacetic acid by keto-group?
A. Nа
B. NaOH
C. *NaHSO3
D. SОCl2
E. NaHCO3
Which of the following reagents will react with acetoacetic acid by keto-group?
A. NaOH
B. *NH2OH
C. SОCl2
D. Nа
E. NaHCO3
Which of the following reagents will react with acetoacetic acid by keto-group?
A. Nа
B. NaHCO3
C. NaOH
D. SОCl2
E. *NH3
Which of the following reagents will react with acetoacetic acid by keto-group?
A. SОCl2
B. NaHCO3
C. NaOH
D. *HCN
E. Nа
Which of the following reagents will react with acetoacetic acid by keto-group?
A. *NH2NH2
B. NaHCO3
C. NaOH
D. SОCl2
E. Nа
Which of the following reagents will react with acetoacetic acid by keto-group?
A. NaHCO3
B. *NH2NHC6H5
C. NaOH
D. SОCl2
E. Nа
Which of the following reagents will react with acetoacetic acid by keto-group?
A. NaOH
B. NaHCO3
C. *NH2NHC(O)NH2
D. SОCl2
E. Nа
143.
Which of the following reagents will react with acetoacetic acid by keto-group?
A. SОCl2
B. NaHCO3
C. NaOH
D. *NH2NHC(S)NH2
E. Nа
144.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. Ag(NH3)2OH
B. NH2NH2
C. NH2OH
D. C6H5NHNH2
E. *NaHCO3
145.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. *NaOH
B. Ag(NH3)2OH
C. NH2OH
D. C6H5NHNH2
E. NH2NH2
146.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. Ag(NH3)2OH
B. NH2OH
C. *Na2CO3
D. C6H5NHNH2
E. NH2NH2
147.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. Ag(NH3)2OH
B. *Na
C. NH2OH
D. C6H5NHNH2
E. NH2NH2
148.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. Ag(NH3)2OH
B. NH2NH2
C. NH2OH
D. C6H5NHNH2
E. *C2H5OH
149.
Which of the following reagents will react with acetoacetic acid by carboxylic group?
A. Ag(NH3)2OH
B. C6H5NHNH2
C. NH2OH
D. *CH3OH
E. NH2NH2
150.
γ-Aminobutyric acid takes part in the brain metabolism, is a neuromediator. What
substances important for the medicine will γ-aminoacids form at the heating?
A. *lactames
B. unsaturated acids
C. diketopiperazine
D. lactides
E. lactones
151.
At the heating of α–aminoacids will form:
A. lactones
B. lactides
C. *diketopiperazine
D. esters
E. unsaturated aminoacids
152.
What compound after the heating does form lactame?
A. 3-aminobutanoic acid
B.
C.
D.
E.
*4-aminobutanoic acid
3-hydroxypentanoic acid
4-amonobenzoic acid
3-aminopropanoic acid
153.
Tyrosine belongs to the aromatic aminoacids. Choose the most correct systematic name
foe tyrosine:
A. *2- amino – 3-(p-hydroxyphenyl) propanoic acid
B. α- amino-2-hydroxyphenyl propanoic acid
C. α-amino-4-hydroxyphenyl propanoic acid
D. 2-amino-3-hydroxyphenyl propanoic acid
E. 2-amino-3-(m-hydroxyphenyl) propanoic acid
154.
Which of the following acids includes asymmetric carbon atom and has optical activity?
A. (СН3)2-С(ОН)-СООН (α-hydroxyisobutyric acid)
B. С6Н5СН2СООН (phenylacetic acid)
C. СН3-С(О)-СООН (pyruvic acid)
D. *СН3-СН(NН2)-СООН (α-aminopropionic acid)
E. СН2=СН-СООН (acrylic acid)
155.
Choose acid, which forms γ-lactone after the heating?
A. malic
B. glycolic
C. lactic
D. pyruvic
E. *4-hydroxybutyric
156.
Alanine – aminoacid enters to the protein structure. Choose reagent, which can help to
confirm presence of amino-group:
A. *NaNO2 (HCl)
B. H2SO4
C. NaNO3 (HCl)
D. Ba(OH)2
E. NaHCO3
157.
Choose reagent that is used to protect amino-group of alanine:
A. CH3–CH2–Cl
B. CH3OH
C. *CH3COCl
D. CH3–NH2
E. CH3–CHO
158.
What reaction is used for deamination of α-aminopropionic acid?
A. etherification
B. with formaldehyde
C. salts formation
D. *with nitrite acid
E. acylation
159.
Aromatic aminoacids can be detected by the usage of the specific reaction:
A. biuret reaction
B. *xantoprotein sample
C. at the boiling with alkalis with following adding of lead acetate
D. with Felling reagent
E. interaction with ninhydrin
160.
Point, which of the following w-aminoacids contains imidazole cycle:
A. alanine
B. tryptophan
C. tyrosine
D. glycine
E. *histidine
161.
What reagent can be used to confirm presence of the primary amino-group in the
serotonin molecule?
A. AgNO3 and NH4OH
B.
C.
D.
E.
*NaNO2 (H+)
Br2
NaHCO3
H2N-NH2
162.
Chose reaction of phosgene obtaining:
A. СО2 + Н2О >
B. С + Н2 + Cl2 >
C. *СО + Cl2 >
D. СО2 + Cl2 >
E. Cl2 + СН4 >
163.
Process 2NH3 + CO2 > cases formation of:
A. Ether of carbaminic acid
B. Carbaminic acid
C. Uretane
D. Methyl urea
E. *Urea
164.
Which of the following reactions will case formation of methane sulfoacid?
A. СН4 + SO2 >
B. *СН4 + SO3 > (at the presence of H2SO4 conc.)
C. С + Н2 + SO2 >
D. СO2 + Н2O + SO2 >
E. СН4 + SO2 > (at the higher pressure)
165.
What reaction will case formation of benzene sulfoacid?
A. *C6H6 + H2SO4 > (oleum)
B. C6H6 + SO3 >
C. C6H6 + SO2 >
D. C6H6 + S + O2 >
E. C6H6 + SO2 + H2O >
166.
1,3,5-benzene trisulfonic acid forms as a result of double sulfonation of benzene
sulfoacid. Choose the mechanism of this reaction.
A. AN
B. SN1
C. SN2
D. *SE
E. AE
167.
As a result of melting of sulfoacids with alkalis the following compounds form:
A. Sulfites
B. Sulfates
C. Hydrosulfates
D. *Sulfonates
E. Carbonates
168.
What compound can be obtained by the following reaction? СО + Cl2 >
A. Urethane
B. Chlorocarbonic acid
C. *Phosgene
D. Carbamide
E. Carbaminic acid
169.
Benzolsulfoacid reduces to:
A. Sulfur and toluene
B. Sulfur oxide (VІ)
C. Benzene and sulfur
D. Sulfur oxide (ІV)
E. *Thiophenol
170.
For arenesulfoacids the following reactions are characteristic:
A. AE,AN
B. *SE,SN
C. SE,AN
D. [O]
E. [H],AE
171.
One of the products of arenesulfoacid hydrolysis is:
A. SO2
B. S
C. H2S
D. *H2SO4
E. H2SO3
172.
Carbonate acid Н2СО3 is unstable. What products will form after its decomposition?
A. 2СО2 +Н2
B. НСОН + Н2О
C. *СО2 + Н2О
D. СО + Н2О
E. НСООН + Н2О
173.
Carbamide hydrolyses with formation of:
A. CO2 + 2N2
B. *CO2 + 2NH3
C. CO2 + H2O + N2
D. CO2 + NO + H2
E. CO + NO2 + H2
174.
Few soluble in water urea nitrate forms at the action on carbamide:
A. *Nitrate acid
B. Nitrogen oxide (V)
C. Nitrogen oxide (ІІІ)
D. Nitrite acid
E. Potassium nitrate
175.
N–acyl derivatives of urea are called:
A. Carbamides
B. Urethanes
C. Anhydrades
D. *Ureides
E. Halogenanhydrides
176.
As a result of biuret reaction that is used for the detection of urea and proteins will
form:
A. Red color complex
B. Green color complex
C. *Red-purple complex
D. Yellow precipitate
E. Blue precipitate
177.
Barbituric acid is in the base of medical drugs – barbiturates. It belongs to:
A. Aliphatic ureides
B. *Cyclic ureides
C. Uretanes
D. Anhydrides
E. Carbamides
178.
During the biuret reaction the following side product forms:
A. *Cyanuric acid
B. Cyanide acid
C. Potassium hexacyanoferrate (ІІ)
D. Potassium hexacyanoferrate (ІІІ)
E. Potassium cyanide
179.
What reaction does case formation of sulfoacid?
A. Sulfochlorination
B. Oxidation of thiols
C. *Oxidation of alcohols
D. Alkanes sulfonation by oleum
E. Accession of hydrosulfites to alkenes
180.
What reagents will interact with sulfoacids to confirm its acidic properties?
A. Cu
B. *NaOH
C. NO2
D. HCl
E. NH3
181.
Mixture of o- and p-toluene sulfonic acids will form as a result of sulfonation. Choose the
mechanism of this reaction.
A. AN
B. SN1
C. SN2
D. *SE
E. AE
182.
Sodium benzolsulfonate will form as a result of interaction of:
A. C6H5SO2OH + Na + O2 >
B. C6H5SO2OH + Na2O2 >
C. C6H5SO2OH + Na2O >
D. C6H5SO2OH + Na >
E. *C6H5SO2OH + NaOH >
183.
Chloroanhydrides of carbonate acids will form as a result of interaction of sulfoacids
with:
A. CHCl3
B. HClO3
C. Cl2
D. *PCl5
E. HCl
184.
Sodium benzolsulfonate is a primary compound for the obtaining:
A. *Phenols, nitrites
B. Amides, nitrocompounds
C. Alcohols, nitrocompounds
D. Phenols, halogenderivatives
E. Amides, halogenderivatives
185.
Choose the mechanism of benzene sulfonation (formation of benzolsulfoacid):
A. AN
B. SN1
C. SN2
D. *SE
E. AE
186.
Which reagent can be used in the following reaction?
A.
B.
C.
187.
D.
E. *
Which is the end-product of the reaction of hydrazine with maleic dialdehyde?
A. *
B.
C.
D.
E.
188.
Which is the product of pyridazine reaction with hydrochloric acid excess?
A.
B.
C. *
D.
E.
189.
Select the mechanism of the following reaction and the position of quinoline it will
principally occur?
A.
B. *
C.
D.
E.
190.
What is the product of the following reaction?
A.
B.
C. *
D.
E.
191.
What is the product of indigo Blue reduction with glucose solution?
A.
B.
C.
D.
E.
indoxyl
pyrrole
indole
*white indigo
isatin
192.
Choose the correct range of aromaticity decrease for furan, benzene, pyrrole, and
thiophene.
A.
B.
C.
D.
193.
E. *
What is the product of the following reaction?
A. *
B.
C.
D.
E.
194.
Which of the following compounds are used for pyrrole acetylation?
A.
B.
C.
D.
E. *
195.
The derivatives of which heterocycle are formed as the result of the following reaction
(Paale-Knorr synthesis)?
A.
B.
C.
D.
E.
2-aminothiazole
indole
thiazole
*thiophene
furane
196.
What heterocyclic compound is formed when diammoniac salt tetrahydroxyadipic acid
is heated?
A.
B.
C.
D.
E.
thiazole
aziridne
*pyrrole
pyrazole
azetidine
197.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Haloperidol - neuroleptic:
A.
B.
C.
D.
E.
acridine
isoquinoline
quinoline
*piperidine
pyridine
198.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Ftivazide (phthivazide) - antimycobacterial drug:
A.
B.
C.
D.
E.
acridine
isoquinoline
quinoline
piperidine
*pyridine
199.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Cordiamin - CNS stimulant:
A.
B.
C.
D.
E.
acridine
benzo[n]pyridine
piperidine
*pyridine
benzo[n]pyrone-2
200.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Neocoumarin - anticoagulant:
A.
B.
C.
D.
E.
acridine
benzo[с]pyridine
piperidine
pyridine
*benzo[в]pyrone-2
201.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Lobelin - alkaloid, analeptic:
A.
B.
C.
D.
E.
202.
A.
B.
acridine
isoquinoline
quinoline
*piperidine
α-pyrone
What is the product of the following reaction?
C. *
D.
E.
203.
Choose the correct range of acidity decrease for the following compounds.
A.
B.
C.
D.
E.
4, 3, 2, 1
1, 3, 2, 4
3, 1, 2, 4
*4, 2, 3, 1
1, 2, 3, 4
Which type of tautomerism is possible for indoxyl?
A.
B.
C.
D.
E.
amino-imine
nito-aci-nitro
azole
*keto-enol
lactam-lactim
What is the product of pyrrole nitration?
204.
205.
A.
B.
C. *
D.
E.
206.
Choose the product of the following reaction.
A.
B.
C. *
D.
E.
207.
Select the mechanism of the following reaction and the position of coumarin it
will principally occur?
A.
B.
C.
D. *
E.
208.
Select the mechanism of the following reaction and the position of acridine it will
principally occur?
A.
B.
C. *
D.
E.
209.
Which is the product of the following reaction?
A.
B.
C.
D.
210.
E. *
Which is the product of the following reaction?
A.
B. *
C.
D.
E.
211.
Which is the product (4) of N-phenylanthranilic acid cyclization?
A.
B. *
C.
D.
E.
212.
Which is the product (2) of the following cyclization?
A.
B.
C. *
D.
E.
213.
Which is the identity of the end-product (№3) in the following scheme?
A.
B. *
C.
D.
E.
214.
Which reaction is Yuriev’s cycle reaction?
A.
B.
C.
D. *
E.
215.
Which of the following conpounds can be starting compounds for pyrrole synthesis?
A.
B.
C.
D.
E.
216.
acetoacetic ester
acetylene
diazomethane
glyoxal, ammonia, formaldehyde
*diammoniac salt tetrahydroxyadipic acid
Which of the following reagents can be used for nitration of acidophobic heterocycles?
A. *
B.
C.
D.
E.
217.
The derivatives of which heterocycle are formed as the result of the following reaction
(Paale-Knorr synthesis)?
A. indole
B. imidazole
C. pyrazole
D. *pyrrole
E. furane
218.
The derivatives of which heterocycle are formed as the result of the following reaction
(Paale-Knorr synthesis)?
A.
B.
C.
D.
E.
pyrrole
isooxazole
oxazole
thiophene
*furane
At what position of indole will electrophilic substitution reactions principally
A.
B.
C.
D.
E.
position 5
position 4
*position 3
position 2
position 1
Which is the product of the following reaction?
219.
occur?
220.
A. *
B.
C.
D.
E.
221.
Choose the product of the following reaction.
A.
B. *
C.
D.
E.
222.
Choose the product of the following condensation.
A.
B. *
C.
D.
E.
223.
Which of the following compound can be classified as azoles?
antipyrine
pyrrole
azetidine
*thiazole
aziridine
224.
Select the mechanism of the following reaction and the position of quinoline it will
principally occur?
A.
B.
C.
D.
E.
A. *
B.
C.
D.
E.
225.
Which is the identity of the intermediates (A and B) in the following scheme?
A.
B.
C. *
D.
E.
226.
Which of the following reactions does lead to the barbituric acid formation?
A.
B.
C. *
D.
E.
227.
At what position of pyrimidine will electrophilic substitution reactions (SE) principally
occur?
A.
B.
C.
D.
E.
*the fifth
the fourth
the third
the second
the first
228.
Which of the following heterocycle is the structural fragment of the substance presented
below (make the accordance of the substance name with the name of proper heterocyclic
moiety)? Rivanol - antiseptic :
A.
B.
C.
D.
E.
229.
A.
B.
C.
*acridine
isoquinoline
quinoline
piperidine
α-pyrone
Which reaction characterize the basic properties of purine?
D.
230.
E. *
Choose the product of pyrazine oxidation?
A.
B. *
C.
D.
E.
231.
What is the product of pyrazine reduction with sodium in ethanol?
A.
B. *
C.
D.
E.
232.
What is the identity of the intermediate (A) and the end-product (B) in the
reaction of ethylenediamine with glyoxal?
A.
B. *
C.
D.
E.
233.
What is the end-product of diethylmalonate condensation with urea?
A.
B. *
C.
D.
E.
234.
Select the mechanism of the following reaction and the position of isoquinolin it will
principally occur?
A.
B.
C.
D. *
E.
235.
At what positions of quinoline will the following reaction principally occur?
A.
B.
C. *
D.
E.
236.
What is the product of indigo Blue oxidation with conc. HNO3?
A.
B.
C.
D.
E.
indoxyl
pyrrole
indole
*isatin
white indigo
237.
The condensation of which compounds leads to formation of
polyvinylpirrolidone?
A.
B.
C.
D.
E.
238.
cycle?
furane with ethene
pyrrole with ethylene
pyrrole with acetylene
pyrrolidone with ethylene
*pyrrolidone with acetylene
Which of the following compound can be used as catalyst in the reactions of Yuriev’s
A.
B.
C.
D.
E. *
239.
Which of the following compounds will form oxiran when treated with concentrated
solution of alkali?
A.
B.
C.
D.
240.
E. *
Which group of alkaloids does theophylline belongs to?
A.
B.
C.
D.
E.
241.
isoquinoline and phenanthroisoquinoline alkaloids
*purine alkaloids
tropane alkaloids
pyridine and piperidine alkaloids
quinoline alkaloids
Choose the correct name for theophylline.
A.
B.
C.
D.
E.
242.
A.
B.
C.
D.
E.
243.
alkaloids?
5,7- dimethylxanthine
3,5- dimethylxanthine
2,4- dimethylxanthine
4,6- dimethylxanthine
*1,3-dimethylxanthine
Choose the most complete definition of alkaloids.
Alkaloids – naturally occurring (plants) oxygencontaining organic compounds.
Alkaloids – naturally occurring (plants and animals) compounds, which display basic
properties.
Alkaloids – heterocyclic compounds with one or more hydroxyl-groups.
Alkaloids – nitrogencontaining organic compounds with glycosidic bonds
*Alkaloids – naturally occurring (plants) nitrogencontaining organic compounds, which
display basic properties and high level of biological activity.
Which of the following reagent can be used to confirm the basic properties of
A.
B.
C. *
D.
E.
244.
Which of the following reactions result purine?
A.
B.
C.
D.
E. *
245.
Which is the identity of the intermediate (A) and the end-product (B) in the following
scheme?
A.
B.
C.
D. *
E.
246.
Choose the product of purine reaction with hydrochloric acid?
A.
B.
C. *
D.
E.
247.
For which purine derivative lactam-lactim tautomerism is possible?
A.
B.
C. *
D.
E.
248.
Which salt is formed when uric acid react with alkali?
A.
B.
C.
D. *
E.
249.
What reaction can be used to identify uric acid?
A.
B.
C.
D.
E.
250.
A.
xanthoprotein test
*murexide test
indophenine test
xanthogenic test
isonitrile test
Choose the product of the following reaction.
B.
C. *
D.
E.
251.
Which of the following reaction result piperidine?
A.
B.
C.
D. *
E.
252.
Which end-product is formed when β -picoline (1) first treated with PCl5, and
then with NH3?
A.
B.
C.
D.
E.
picolinic acid amide
*nicotinamide (vitamin PP)
isonicotinamide
ammonium salt of nicotinic acid
ammonium salt of isonicotinic acid
253.
Select the mechanism of the following reaction and the position of quinoline it will
principally occur?
A.
B.
C.
D. *
E.
254.
Which is the end-product of acridine oxidation?
A.
B. *
C.
D.
E.
255.
Which is the end-product of isoquinoline oxidation?
A. *
B.
C.
D.
E.
256.
What is the end-product of the following reaction?
A.
B.
C.
D. *
E.
257.
Choose the proper pair of products of the following reaction.
A.
B.
C.
D. *
E.
258.
Choose the product of the following reaction.
A.
B.
C.
D. *
E.
259.
Which is the end-product of acrolein condensation?
A.
B. *
C.
D.
E.
260.
Which of the following compounds can be used for furan sulfonation?
A.
B. *
C.
D.
E.
261.
Which is the product of pyrazole reduction with hydrogen according to the
following scheme?
A.
B.
C.
D. *
E.
262.
Which is the identity of the end-product (4) in the following scheme?
A.
B.
C.
D.
E.
263.
A.
B.
C.
D.
4-nitrofurfural semicarbazone
3-nitrofurfural
5-nitrofurfural diacetate
5-nitrofurfural
*5-nitrofurfural semicarbazone
Which of the following compounds is indole?
E. *
264.
Which reagent can be used to proof the presence of keto-group in isatin
molecule?
A.
B.
C. acid fuchsine sulfite
D.
265.
E. *
What is the product of the following reaction?
A.
B.
C.
D.
E.
N- methylpyrrole
N- acetylpyrrolium chloride
b-acetylpyrrole
a-acetylpyrrole
*N-acetylpyrrole
266.
Which is the identity of the intermediate (X) and the end-product (Y) in the
following scheme?
A.
B.
C. *
D.
E.
267.
Choose the correct range of SE reactivity decrease for thiophene, furan, benzene, and
pyrrole.
A.
B.
C. *
D.
E.
268.
Which of the following heterocycle is acidophobic?
A.
B.
C.
D. *
E.
269.
What is the identity of the end-product 2 in the following scheme?
A.
B.
C. *
D.
E.
270.
Which of the following heterocycle is acidophobic?
A.
B. *
C.
D.
E.
271.
Which reaction is Yuriev’s cycle reaction?
A.
B.
C.
D. *
E.
272.
Which of the following heterocycle is aromatic?
A.
B. *
C.
D.
E.
273.
Which type of isomerism is possible for pyrazole and imidazole?
A.
B.
C.
D.
E.
nitro-aci-nitro
*azole
keto-enol
amino-imino
lactam-lactim
274.
Which is the identity of the intermediate (A) and the end-product (B) in the following
scheme?
A.
B.
C. *
D.
E.
275.
Choose the correct systematic name of purine.
A.
B.
C.
D.
E.
276.
A.
B.
C.
*imidazo[4,5-d] pyrimidine
pyrazolo[4,5-d] pyrimidine
pyridino[4,5-d]pyrimidine
pyrimidino[4,5-d]imidazole
pyridazo[4,5-d]pyrimidine
What starting compound is required for barbituric acid synthesis?
D. *
E.
277.
Which of the following reactions lead to pyrimidine formation?
A.
B.
C. *
D.
E.
278.
Which of the following reaction is impossible?
A.
B.
C.
D. *
E.
279.
Which of the following reactions lead to pyrazine?
A.
B.
C. *
D.
E.
280.
Which of the following reaction lead to coumarin formation?
A.
B.
C.
D. *
E.
281.
Which of the following pyrimindine derivative shall undergo the electrophilic
substitution reactions?
A.
B.
C.
D. *
E.
282.
Choose the correct way for purine atoms numbering.
A.
B.
C.
D. *
E.
283.
At what positions of pyridine N-oxide will electrophilic substitution reactions (SE)
principally occur?
A.
B.
C.
D.
E.
284.
occur?
1, 4
3, 5
*2, 4, 6
1, 4, 6
1, 3, 5
At what position of pyridine shall electrophilic substitution reactions (SE) principally
A.
B.
C.
D.
E.
6
4
*3
2
1
285.
At what positions of pyridine will nucleophilic substitution reactions (SN)
principally occur?
A.
B.
C.
D.
E.
286.
A.
B.
3, 5
2, 5
1, 3, 5
*2, 4, 6
2, 4, 5
Choose the product of the following reaction.
C. *
D.
E.
287.
occur?
At what position of pyrazole will reaction with nitric acid (heat) principally
A.
B.
C.
D.
E.
288.
position 5
*position 4
position 3
position 2
position 1
Choose the structure of analgin.
A.
B. *
C.
D.
E.
289.
Which is the identity of the end-product (3) in the following scheme?
A.
B. *
C.
D.
E.
290.
Which reagent shall react with cyclic nitrogen atom of 2-aminothiazole?
A.
B.
C.
D.
291.
E. *
Which is the identity of the end-product (№3) in the following scheme?
A.
B.
C.
D. *
E.
292.
Which is the starting reagent in the synthesis of 5-methyl-1-phenylpyrazolone-5?
A.
B.
C.
D.
E.
293.
ethyl acetate
diethyl malonate
acetic acid
*acetoacetic ester
ethyl propionate
At what position of pyrazole will reaction with CH3I principally occur?
A.
B.
C.
D.
E.
294.
position 5
position 4
position 3
*position 2
position 1
What is the product of imidazole sulfonation?
A.
B.
C. *
D.
E.
295.
Which of the following compound can be used for furane chlorination?
A.
B.
C.
D.
296.
E. *
Which of the following heterocycle is acidophobic?
A.
B.
C. *
D.
E.
297.
What is the end-product of reaction of potassium-pyrrolide with iodomethane?
A.
B.
C.
D.
E.
α,α’-dimethylpyrrole
α,β-dimethylpyrrole
β- methylpyrrole
*α-methylpyrrole
N-methylpyrrole
Which statement about furfural is not true?
A.
B.
C.
D.
E.
*it forms a-furamide with NH3
it forms hydrofuramide with NH3
it undergoes Cannizzaro reaction
can be obtained from aldopentose
it undergoes SE reactions at position 5
Which of the following heterocycle is acidophobic?
298.
299.
A.
B.
C.
D. *
E.
300.
Which of the following reactions lead to formation of thiophene?
A.
B.
C.
D. *
E.
301.
Three- and four-membered heterocycles, such as oxetane, aziridine, and azitidine are:
A. heterocycles with three heteroatoms
B. heterocycles with two heteroatoms
302.
C. aromatic heterocycles
D. unsaturated heterocycles
E. *saturated heterocycles
Which of the following compounds can be cyclized to aziridine?
A. *
B.
C.
D.
E.
303.
Which reaction characterize aziridine as secondary cyclic amine?
A.
B.
C.
D.
304.
E. *
Which reaction does oxiran undergo?
A.
B.
C.
D.
E.
305.
electrophilic addition
electrophilic substitution
nucleophilic substitution
free-radical substitution
*nucleophilic addition
Choose the products of the following reaction.
A.
B.
C. *
D.
E.
306.
Which of the following reaction of oxiran are possible?
A.
B.
C. *
D.
E.
307.
Choose the mechanism of the following reaction:
A.
B.
C.
D. *
E.
308.
Heterocyclic compound pyrrole belongs to:
*fivemember heterocycles with one heteroatom
fivemember heterocycles with two heteroatoms
sixmember heterocycles with one heteroatom
fivemember heterocycles with two heteroatoms
condensed heterocycles
309.
Heterocyclic compound pyrrole is a part of:
A. anesthetic means
B. nucleic acids
C. preparations for the tuberculosis treatment
D. bactericide means
E. *hem of hemoglobin
310.
According to the level of saturation heterocyclic compounds are divided on:
A. condensed and non-condensed
B. *saturated, unsaturated, aromatic
C. azoth containing, oxygen containing, sulfur containing
D. fivemember, sixmember, sevenmember
E. cycles with one and two heteroatoms
311.
According to the nature of heteroatom heterocyclic compounds are divided on:
A. saturated, unsaturated, aromatic
B. *nitrogen containing, oxygen containing, sulfur containing
C. fivemember, sixmember, sevenmember
D. cycles with one and two heteroatoms
E. condensed and non-condensed heterocycles
312.
3- and 4-member heterocycles oxethane, azeridine, azetidine are:
A. *saturated heterocycles
B. unsaturated heterocycles
C. aromatic heterocycles
D. heterocycles with tree heteroatoms
E. heterocycles with trwo heteroatoms
313.
How does pyrrole basic properties change in the comparison with the products of its
partial and complete reduction?
A. does not change
B. *increases from pyrrole to pyrolidine
C. increases in the row of pyrolidine, pyroline, pyrrole
D. decreases in the row of pyroline, pyrolidine, pyrrole
E. increases in the row of pyrolidine, pyrrole, pyrroline
314.
Nitrogen atom in the pyrrole molecule can react with:
A. *potassium amide
B. potassium chloride
C. potassium sulfate
D. sulfate acid
E. chloride acid
315.
For three- and fourmember heterocycles the following types of reactions are
characteristic:
A. radical substitution
B. electrophilic and nucleophilic substitution
C. *electrophilic and nucleophilic accession
D. radical accession
E. polymerization
316.
According to the size of cycle (total number of atoms in the cycle) heterocyclic
A.
B.
C.
D.
E.
compounds can be classified on:
A. saturated, unsaturated, aromatic
B. azoth containing, oxygen containing, sulfur containing
C. *fivemember, sixmember, sevenmember
D. cycles with one or two heteroatoms
E. condensed and non-condensed heterocycles
317.
To fourmember heterocyclic compounds with one atom of oxygen belongs the following
one:
A. *oxethane
B. pyrazole
C. oxyrane
D. pyrimidine
E. pyridine
318.
To threemember heterocyclic compounds with one atom of oxygen belongs the following
one:
A. pyrimidine
B. oxethane
C. *oxyrane
D. pyrrole
E. pyridine
319.
To fourmember heterocyclic compounds with one atom of sulfur belongs the following
one:
A. thiophene
B. pyrazole
C. pyrrole
D. pyridine
E. *thiethane
320.
To threemember heterocyclic compounds with one atom of sulfur belongs the following
one:
A. thiophene
B. thiethane
C. pyrrole
D. *thiirane
E. pyridine
321.
What compound with concentrated alkali solution will form oxyrane?
A. *HOCH2—CH2—Cl
B. HOCH2—CH2—CH2—Cl
C. H2C=CH2
D. HOCH2—CH2—OH
E. H3C—CH3
322.
Among of the following compounds choose nitration reagent for the acidophobic
compounds:
A. HNO3 conc
B. CH3COOH
C. H3BO3
D. NaNO2 + HCl
E. *(CH3CO)2O + HNO3
323.
To fivemember heterocyclic compounds with one atom of sulfur belongs the following
one:
A. pyrimidine
B. pyrazole
C. pyrrole
D. *thiophene
E. pyridine
324.
To fivemember heterocyclic compounds with one atom of nitrogen belongs the following
one:
A. pyridine
B.
C.
D.
E.
pyrazole
*indole
furane
pyrimidine
325.
Furacilline – medical drug that is used for the treatment of pyoinflammatory processes
cased by microorganisms. What heterocycle is a primer compound for furacilline synthesis?
A. pyrrole
B. *furan
C. thiophene
D. imidazole
E. pyridine
326.
Furfural (2-furylcarbaldehyde) – primer compounf for the synthesis of furacilline,
furazolidone and furadonine. Choose reagent that can be used to obtain semicarbazone.
A. H2N–C6H5
B. H2N–OH
C. *H2N–NH–C(O)–NH2
D. H2N–NH–C(S)–NH2
E. H2N–NH2
327.
5 – nitrofurfural is a primer compound for the synthesis of furacilline, furazolidone and
furadonine. Choose the type of reaction of furfural nitration by conc. nitrate acid in the
medium of acetic anhydride?
A. AN
B. SR
C. E
D. SN
E. *SE
328.
5 – nitrofurfural is a primer compound for the synthesis of furacilline, furazolidone and
furadonine. Choose the mechanism of furfural nitration by conc. nitrate acid in the medium of
acetic anhydride?
A. *radical
B. ionic
C. nucleophilic
D. substitutin by m-position
E. substitutin by o- and p-position
329.
Choose compound, which with 5-nitrofurfural forms furacilline.
A. *semicarbazide
B. phenylhydrazide
C. hydrazine
D. hydraxylamine
E. sodium hydrosulfite
330.
Nitrogen atom in the pyrrole molecule can react with:
A. *potassium amide
B. potassium chloride
C. potassium sulfate
D. sulfate acid
E. chloride acid
331.
Choose the more correct name for complete thiophene hydration:
A. 1,2,3,4,5-pentahydrothiophene
B. 2,3-dihydrothiphene
C. 1,2-dihydrothiophene
D. 3,4-dihydrothiophene
E. *2,3,4,5-tetrahydrothiophene
332.
Which of the following substances can not be sulfonated with concentrated sulfate acid?
A. thiophene
B. pyridine
C. toluene
D. *pyrrole
E. naphthalene
333.
Which of the following substances has acidophobic properties?
A. pyridine
B. pyrazole
C. *pyrrole
D. pyrimidine
E. imidazole
334.
Name product of the pyrrole sulfonation:
A. 3-pyrrole sulfoacid
B. *2-pyrrole sulfoacid
C. 4-pyrrole sulfoacid
D. 5-pyrrole sulfoacid
E. 1-pyrrole sulfoacid
335.
Choose the reagent for furan nitration:
A. HNO3; H2SO4
B. HNO3 (dil.)
C. HNO3 (conc.)
D. *CH3COONO2
E. HNO2
336.
Pyrrole and furan are sulfonated by:
A. concentrated sulfate acid
B. *pyridinesulfotrioxide
C. diluted sulfate acid
D. mixture of sulfate and nitrate acids
E. oleum
337.
To fivemember heterocyclic compounds with one atom of nitrogen belongs the following
one:
A. pyrimidine
B. pyrazole
C. *pyrrole
D. furan
E. pyridine
338.
Which of the following reagents will react with pyrrole by heteroatom?
A. *NaNH2
B. СН3СОOH
C. (CH3CO)2O
D. SnCl4
E. SO2Cl2
339.
Weak acidic properties the following heterocyclic compound has:
A. pyridine
B. thiophene
C. quinoline
D. furane
E. *pyrrole
340.
To fivemember heterocyclic compounds with one atom of oxygen belongs the following
one:
A. pyrimidine
B. pyrazole
C. pyrrole
D. *furane
E. pyridine
341.
To fivemember heterocyclic compounds with one atom of sulfur belongs the following
one:
A. pyrimidine
B. *thiphene
C. pyrrole
D. pyrazole
E. pyridine
342.
Heterocyclic compound pyrrole belongs to:
A. *fivemember heterocycles with one heteroatom
B. fivemember heterocycles with two heteroatoms
C. sixmember heterocycles with one heteroatom
D. fivemember heterocycles with two heteroatoms
E. condensed heterocycles
343.
Heterocyclic compound pyrrole is a part of:
A. anesthetic means
B. nucleic acids
C. preparations for the tuberculosis treatment
D. bactericide means
E. *hem of hemoglobin
344.
What substance will form as a result of interaction of acetoacetic ester with
phenylhydrazine?
A. Amidopyrine
B. Analgin
C. Antipyrine
D. *3-methyl-1-phenylpyrazolone-5
E. 2,3-dimethyl-1-phenylpyrazolone-5
345.
What substance will form as a result of interaction of 4-methylaminoantipyrine with
formalin and sodium hydrosulfite?
A. Amizon
B. Antipyrine
C. Aspirin
D. *Analgin
E. Amidopyrine
346.
1,3-diazol is isomer of:
A. Indole
B. Benzimidazole
C. *Pyrazole
D. Pyrole
E. Pyridine
347.
1,2-diazole is isomer of:
A. Indole
B. Benzimidazole
C. *Imidazole
D. Pyrole
E. Pyridine
348.
Oxazole is isomer of:
A. Azole
B. Thiazole
C. Furan
D. *Isooxazole
E. Pyrrole
349.
Which of the following heterocycles does belong to azoles?
A. Indole
B. *Thiazole
C. Thiophene
D. Pyrrole
E. Furan
350.
Which of the following heterocycles has basic properties?
A. *Pyrazole
B. tetrahydrofurane
C. Thiophene
D. Pyrolidine
E. Pyrroel
What heterocycle is in the content of vitamin В1 (thiamin)?
A. Thiophene
B. Pyridine
C. *Thiazole
D. Oxazole
E. Purine
352.
Which of the following medical compounds does contain imidazole heterocycle?
A. analgin
B. *histidine
C. antipyrine
D. amidopyrine
E. furacilline
353.
If oxazole cycle is activated by electronodonor subtitution the reactions of SE takes
place. Specify the position, by which this reaction will go:
A. 3 and 2
B. 2 and 5
C. *4 and 5
D. 3 and 4
E. 2 and 1
354.
What reaction does case pyrazole formation?
A. Intramolecular dehydration of ethanol
B. Melting with alkali solution of benzolsulfoacid
C. Cyclotrimerization of acetylene
D. Pentose dehydratation
E. *Accession of diazoalkanes to acetylenes
355.
What reaction does case pyrazole formation?
A. Intramolecular dehydration of ethanol
B. Melting with alkali solution of benzolsulfoacid
C. Cyclotrimerization of acetylene
D. Pentose dehydratation
E. *Interaction of hydrazine with pentadione-2,4
356.
Pyrazole according to its physical properties is:
A. Crystalline orange compound
B. Liquid, good soluble in water
C. Gaseous substance
D. *Colorless crystalline compound, good soluble in water
E. Liquid, insoluble in water
357.
Alkylation and acylation of pyrazole conduct with formation of the following products:
A. *N–substitution
B. m–substitution
C. p–substitution
D. o- and p-substitution
E. Mixture of N- and m-substituution
358.
Choose the product of pyrazole reduction:
A. Pyridine
B. Hydropyrazole
C. *Pyrazoline–2
D. Pyrazolidine
E. Pyrrole
359.
Choose the product of pyrazole partial reduction:
A. Pyridine
B. *3,4-dihydropyrazole
C. Hydropyrazole
D. 1-,2-dihydropyrazole
E. Trihydropyrazole
360.
Choose the product of pyrazole complete reduction:
A. Pyridine
351.
B.
C.
D.
E.
Dihydropyrrole
Trihydropyrazole
Pyrrole
*Pyrazolidine
361.
Choose the product of pyrazole complete reduction:
A. Pyridine
B. *Tetrahydropyrazole
C. 3,4-dihydropyrazole
D. Trihydropyrazole
E. Pyrrole
362.
Choose reagent for pyrazole partial reduction:
A. CH3COOH
B. C2H5OH
C. 2H2(Pt)
D. *2H(C2H5OH+Na)
E. KMnO4
363.
Choose reagent for pyrazole complete reduction:
A. CH3COOH
B. 2H(C2H5OH+N
C. *2H2(Pt)
D. C2H5OH
E. KMnO4
364.
Choose chemical name for antipyrine:
A. 4-nitrozoantipyrine
B. *2,3-dimethyl-1-phenylpyrazolone-5
C. 3-methyl-1-phenylpyrazolone-5
D. 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5
E. sodium 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate
365.
Choose chemical name for amidopyrine:
A. 4-nitrozoantipyrine
B. 2,3-dimethyl-1-phenylpyrazolone-5
C. 3-methyl-1-phenylpyrazolone-5
D. *2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5
E. sodium 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate
366.
Choose chemical name for analgin:
A. 4-nitrozoantipyrine
B. 2,3-dimethyl-1-phenylpyrazolone-5
C. 3-methyl-1-phenylpyrazolone-5
D. 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5
E. *sodium 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate
367.
Choose chemical name for sodium methamizole:
A. 4-nitrozoantipyrine
B. 2,3-dimethyl-1-phenylpyrazolone-5
C. 3-methyl-1-phenylpyrazolone-5
D. 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5
E. *sodium 2,3-dimethyl-4-dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate
368.
Choose correct name of the preparation with the chemical name 2,3-dimethyl-1phenylpyrazolone-5:
A. *Antipyrine
B. Aspartic acid
C. Aspirin
D. Amidopyrine
E. Analgin
369.
Choose correct name of the preparation with the chemical name 2,3-dimethyl-4dimethylamino-1-phenylpyrazolone-5:
A. Antipyrine
B. Aspartic acid
C. Aspirin
D. *Amidopyrine
E. Analgin
370.
Choose correct name of the preparation with the chemical name sodium 2,3-dimethyl-4dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate:
A. Antipyrine
B. Aspartic acid
C. *Analgin
D. Amidopyrine
E. Aspirin
371.
Choose correct name of the preparation with the chemical name sodium 2,3-dimethyl-4dimethylamino-1-phenylpyrazolone-5-N-methanesulfonate:
A. *Sodium methamizole
B. Aspartic acid
C. Aspirin
D. Amidopyrine
E. Antipyrine
372.
Analgin is used in the medical practice as:
A. Form of vitamin PP
B. Antibacterial mean
C. *Analgesic mean
D. Vasodilator
E. Drug against tuberculosis
373.
For imidazole obtaining use interaction of the following compounds:
A. Acetoacetic ester and phenylhydrazine
B. *Glyoxal, ammonia, formaldehyde
C. Ethanol and alkali
D. Ethanoic acid and ethyl alcohol
E. Acetylene and ammonium
374.
Imidazole is:
A. Crystalline yellow compound
B. Liquid, insoluble in water
C. *Colorless crystalline compound, good soluble in water
D. Gaseous compound
E. Liquid with sharp smell
375.
To the imidazole derivatives the following compound belongs:
A. *Histidine
B. Vitamin PP
C. Furfural
D. Norsulfazole
E. Cordiamine
376.
To the imidazole derivatives the following compound belongs:
A. Vitamine PP
B. Norsulfazole
C. Furfural
D. *Histamine
E. Cordiamine
377.
To the imidazole derivatives the following compound belongs:
A. Vitamine PP
B. *Pilocarpine
C. Furfural
D. Norsulfazole
E. Cordiamine
378.
Benzimidazole can be obtained by the interaction of:
A. *О-phenylenediamine with formic acid;
B. Acetylene with ammonia
C. Ethanoic acid and ethanol
D. Glyoxal, ammonia, formaldehyde
E. Acetoacetic ester and phenylhydrazine
379.
Benzimidazole has:
A. Oxidative properties
B. Reductive properties
C. Acidic properties
D. *Amphoteric properties
E. Basic properties
380.
Benzimidazole cycle is a part of vitamin:
A. *В12;
B. С;
C. А;
D. Н;
E. РР.
381.
Benzimidazole cycle is a part of the following drug:
A. Analgin
B. *Dibazole
C. Norsulfazole
D. Phthalazol
E. Furacilline
382.
Thiazole is a part of the following natural compound:
A. *Vitamin В1
B. Vitamin С
C. Vitamin А
D. Vitamin РР
E. Vitamin Н
383.
Thiazole is a part of the following natural compound:
A. Vitamin РР
B. Vitamin Н
C. *Penicillin
D. D–carotene
E. itamin С
384.
Thiazole is a part of the following medical drug:
A. Isoniazide
B. Phenobarbital
C. Cordiamine
D. *Norsulfazole
E. Furacilline
385.
Thiazole is a part of the following medical drug:
A. Isoniazide
B. Phenobarbital
C. Cordiamine
D. *Phthalazol
E. Furacilline
386.
A thizole nucleus is a part of natural penicillins. The drug has:
A. Analgesic properties
B. *Antimicrobial properties
C. Vasodilatation activity
D. Bronchodilatation activity
E. Antituberculosis properties
387.
By the presence of free pare of electrons of pyridine type nitrogen atom oxazole has the
following properties:
A. *Weak basic properties
B. Strong basic properties
C. Weak acidic properties
D. Strong acidic properties
E. Amphoteric properties
388.
Isooxazole has the following properties:
A. Amphoteric
B. Strong acidic
C. Weak acidic
D. Strong basic
E. *Weak basic
389.
Qualitative reaction on antipyrine is reaction with:
A. H2
B. HCl
C. NH3
D. CH3OH
E. *FeCl3
390.
Qualitative reaction on antipyrine is intereaction with:
A. H2
B. *NaNO2(H+)
C. NH3
D. CH3OH
E. HCl
391.
Qualitative reaction on antipyrine is reaction with FeCl3. As a result complex salt
(ferropyrine) will form. What is the color of this complex?
A. Red
B. Yellow
C. Brown
D. *Orange
E. Blue
392.
Qualitative reaction on antipyrine is reaction with FeCl3. As a result orange color
complex salt will form. This is:
A. *Ferropyrine
B. Furazolidone
C. Furadonine
D. Furfural
E. Furacilline
393.
Qualitative reaction on antipyrine is reaction with NaNO2(H+). As a result 4–
nitrozoantipyrine will form. This compound has the following color:
A. Colorless
B. Orange
C. Blue
D. Yellow
E. *Emerald-green color
394.
Qualitative reaction on antipyrine is reaction with NaNO2(H+). As a result emeraldgreen compound will form. This is:
A. 3–aminoantipyrine
B. Amidoantipyrine
C. 4–aminoantipyrine
D. 2–nitrozoantipyrine
E. *4–nitrozoantipyrine
395.
Qualitative reaction on amidopyrine is intereaction with:
A. H2
B. *FeCl3 (Н+)
C. CH3OH
D. H2SO4
E. HCl
396.
Qualitative reaction on anmidopyrine is intereaction with:
A. H2
B. *К3[Fe(СN)6] and Fe3+
C. CH3OH
D. H2SO4
E. HCl
397.
Choose the reaction that can be used to distinguish analgin from amidopyrine:
A. H2
B. H2SO4
C. NaNO2
D. *FeCl3 (Н+)
E. HCl,t
398.
Choose the reaction that can be used to distinguish analgin from amidopyrine:
A. H2
B. H2SO4
C. NaNO2
D. *К3[Fe(СN)6] Fe3+
E. HCl,t
399.
As a result of interaction of amidopyrine with К3[Fe(СN)6], in the presence of FeCl3
blue color complex will form with the following content:
A. Fe[Fe(СN)6]
B. *Fe4[Fe(СN)6]3
C. К4[Fe(СN)6]
D. КFe[Fe(СN)6]
E. К2Fe[Fe(СN)6]
400.
To the preparation, which is a derivative of pyrazolone-5, solution of FeCl3 is added.
Observe the appearance of the intense orange coloration. Choose this preparation:
A. Penicilline
B. Anesthesin
C. Amidopyrine
D. *Antipyrine
E. Analgine
401.
As a result of antipyrine nitrozation with the following reduction the next compound will
form:
A. *4-nitrozoantipyrine
B. 2-aminoantipyrine
C. Amidopyrine
D. 3-aminoantipyrine
E. 4-aminoantipyrine
402.
As a result of 4-aminoantupyrine methylation the following compound will form:
A. *Amidopyrine
B. 3-methyl-1-phenylpyrazolone-5
C. 2,3-dimethyl-1-phenylpyrazolone-5
D. 4-nitrozoantipyrine
E. Analgin
403.
Why quinoline and isoquinoline give reactions of eletrophilic substitution previously by
the positions 5 and 8?
A. nitrogen atom has bigger electronegativity than carbon atom
B. *positions 5 and 8 have bigger electronic density
C. nitrogen atom has sp2 –hybridization of the electronic
D. benzene cycle has three double bounds
E. nucleophilic substitution reactions are not possible
404.
For pyridine reactions of electrophilic (SE) nucleophilic (SN) substitution are
characteristic. Lower reaction ability of pyridine in the reactions of SE is caused by:
A. size of the cycle
B. aromatic character of the pyridine cycle
C. basic properties
D. carbon atom hybridization атомів вуглецю
E. *electron acceptor properties of nitrogen atom
405.
How many π-electrons do form aromatic system of pyridine?
A. 14
B. 10
C. *6
D. 8
E. 12
406.
Choose the mechanism of pyridine hydroxylation in position 2:
A. *SN
B. SE
C. AE
D. SR
E. AN
407.
Point the mechanism of the 2-aminopyridine formation by Chichibabin:
A. AR
B. SE
C. AE
D. SN
E. *SR
408.
Choose the way of piperidine from pyridine obtaining in one stage:
A. pyridine amination
B. pyridine nitration
C. pyridine methylation
D. *pyridine hydration
E. pyridine interaction with hydrochloric acid
409.
For pyridine the following reactions are characteristic:
A. electrophilic accession andта electrophilic substitution
B. *electrophilic and nucleophilic substitution
C. nucleophilic accession and nucleophilic substitution
D. nucleophilic substitution and elimination
E. radical substitution and electrophilic accession
410.
Pyridine – aromatic heterocycle, which is a part of many medical drugs. Determine how
many monomethyl substituted pyridines exist.
A. 1
B. 2
C. *3
D. 4
E. 5
411.
According to the Hukel rule quantity of π-electrons in the aromatic system can be
determined by the following formula 4n+2. What number of π-electrones does acridine
molecule contain?
A. 10
B. *14
C. 8
D. 6
E. 12
412.
Nitrogen atom in the pyridine molecule can react with:
A. *hydrochloric acid
B. potassium hydroxyde
C. calcium oxide
D. potassium carbonate
E. potassium amide
413.
Nicotinic acid amide (vitamin РР) is the derivative of:
A. pyrazole
B. thiphene
C. pyrrole
D. furan
E. *pyridine
414.
Acridine gives reactions of electrophilic substitution previously by the position:
A. 2 and 3
B. *2
C. 5
D. 5 and 8
E. 2 and 7
415.
Reactions of electrophilic and nucleophilic substitution in the quinoline nuclei go in the
following positions:
A. SE in position 5, SN – in position 4
B. SE in position 2, SN – in position 4
C. SE in position 3, SN – in positions 2 and 4
D. *SE in positions 5 and 8, SN – in position 2
E. SE in position 6, SN – in positions 3 and 4
416.
After the nicotine oxidation in the hard conditions the following compound will form:
A. pyridine-3,4-dicarboxylic acid
B. pyridine-2-carboxylic acid
C. pyridine-4-carboxylic acid
D. pyridine-2,3-dicarboxylic acid
E. *pyridine-3-carboxylic acid
417.
Derivatives of cyclic and heterocyclic compounds are the structural fragment of the
many medical drugs. Which of the following compounds does not have carbon atom in sp2 –
hybridized state?
A. *piperidine
B. pyridine
C. pyrrole
D. pyroline
E. pyridazine
418.
Which of the following acids is pro-vitamin РР?
A. pycolinic
B. isonicotinic
C. *nicotinic
D. salicylic
E. anthranilic
419.
Which of the following compounds after the oxidation will form nicotinic acid?
A. pyrazine
B. *β-pycoline
C. γ-pycoline
D. propylene glycol
E. α-pyrone
420.
Which of the following cycles is a structural fragment of alkaloid lobeline, anabazine, is
a part of analgesic mean promedol?
A. *piperidine
B. piperazine
C. pyrimidine
D. pyridazine
E. pyridine
421.
Pyrimidine is an aromatic heterocyclic compound; its derivatives are in the content of
nucleic acids, vitamins, antibiotics, medical drugs. Enter the number of electrons involved in
the formation of the closed conjugated system and corresponded to the Huckel’s rule.
A. *6
B. 14
C. 10
D. 26
E. 18
422.
Pyrimidine is an aromatic heterocyclic compound. Determine the number of electrons
that take part in the formation of aromatic system of the pyrimidine molecule:
A. 2
B. 4
C. *6
D. 8
E. 10
423.
Barbituric acid is one of the most important pyrimidine derivatives. What type of
tautomery is characteristic for barbituric acid?
A. Azol and nitro-acy-nitro tautomery
B. Keto-enol and nitro-acy-nitro tautomery
C. Lactam-lactim and nitro-acy-nitro tautomery
D. *Keto-enol and lactam-lactim
E. Cyclic-chain and nitro-acy-nitro tautomery
424.
Pyrazole – aromatic heterocycle. Determine the product of pyrazole interaction with
conc. НNO3 at the heating:
A. 3-Nitropyrazole
B. *4-Nitropyrazole
C. Pyrazolyl nitrate
D. 5-Nitropyrazole
E. 3,5-Dinitropyrazole
425.
Barbituric acid is in the base of some medical preparations. What heterocycle is in the
base of barbituric acid?
A. *Pyrimidine
B. Pyrazine
C. Pyridazine
D. Pyridine
E. Insole
426.
Point the type of tautomery of pyramiding foundations – thymine, uracil, and cytosine:
A. azol
B. nitro-acy-nitro
C. keto-enol
D. thion-thiol
E. *Lactam-lactim
427.
Derivatives of which heterocycle has azol tautomery?
A. pyridazine
B. pyrazine
C. *pyrazole
D. thiazole
E. oxazole
428.
What reaction can be used to obtain pyridazine?
A. Condensation of malondialdehyde with hydrazine
B. *Condensation of maleinedialdehyde with hydrazine
C. Condensation of acetaldehyde with ammonia
D. Condensation of ethylenediamine with glyoxal
E. Diethylmalonate interaction with urea
429.
Choose heterocycle that is in the base of barbituric acid, which derivatives are used in
the medicine as medical drugs and have hypnotic and anticonvulsion action.
A. pyridine
B. pyridazine
C. pyrazine
D. piperidine
E. *pyrimidine
430.
Sixmember azotcontaining heterocyclic compounds have basic properties. Specify the
compound, which has the biggest basic properties.
A. Pyrazine
B. Pyridine
C. Pyrimidine
D. *Piperazine
E. Pyridazine
431.
To the sixmember heterocycles with two nitrogen heteroatoms the following compound
belongs:
A. Pyrrolidine
B.
C.
D.
E.
432.
A.
B.
C.
D.
E.
433.
A.
B.
C.
D.
E.
434.
A.
B.
C.
D.
E.
435.
A.
B.
C.
D.
E.
436.
A.
B.
C.
D.
E.
437.
A.
B.
C.
D.
E.
438.
A.
B.
C.
D.
E.
439.
A.
B.
C.
D.
E.
Purine
*Pyrimidine
Pyrrole
Pyridine
Choose the compound, which derivatives are used in the medicine as hypnotic means:
Pyridine
Nicotinic acid
Xanthine
Uric acid
*Barbituric acid
Derivatives of barbituric acid are used in the medical practice as:
Antipyretic means
Antiseptic means
Antibiotics
*Hypnotic means
Preparations with anti-mycosis action
For diazines is cheracteristic:
The high reactivity in the reactions of Е
Low reactivity in the reactions of SN
The high reactivity in the reactions of SR
The high reactivity in the reactions of SЕ and SN
*The high reactivity in the reactions of SN and low reactivity in the reactions of SЕ
What compound can be obtained by the interaction of maleinealdehyde with hydrazine?
Pyrrole
*Pyridazine
Pyrimidine
Pyrazine
Pyridine
Pyridazine is:
*A weak base
An inert compound
A strong base
A weak acid
a strong oxidant
What compound will form after the pyridazine interaction with HCl?
5-chloropyridazine
3-chloropyridazine
*pyridazinium chloride
pyrimidinium chloride
pyrazinium chloride
What compound will form after the pyridazine interaction with CH3I?
6-methylpyridazine iodide
*N-methylpyridazine iodide
3-methylpyridazine iodide
4-methylpyridazine iodide
5-methylpyridazine iodide
Under the action of peroxyacid (CH3COOOH) pyridazine oxidizes with formation of:
*pyridazine N-oxide
pyrimidine N-oxide
pyrazine N-oxide
pyridazinone-4
pyridazinone-5
At the pyridazine reduction by sodium in alcohol solution the following compound will
440.
form:
A. Butylamine
B. Diethylamine
C. Piperidine
D. *Tetramethylenediamine
E. Pyrimidine
441.
Choose the chemical name of pyrimidine:
A. 1,5-diazine
B. diazepine
C. 1,4-diazine
D. 1, 2-diazine
E. *1,3 -diazine
442.
Choose the mechanism of the reaction of the pyrazine interaction with sodium amide:
A. SE
B. SR
C. *SN
D. E
E. AN
443.
The reaction of the pyrazine interaction with sodium amide will go in the following
position:
A. 5
B. *2
C. 1
D. 3
E. 4
444.
Under the action of peroxyacids pyrazine oxidizes with formation of:
A. *Pyrazine mono-N-oxide
B. Pyrazone-2
C. Pyrazine di-N,N-oxide
D. Pyrazone-3
E. Pyrazone-5
445.
Choose the product of pyrazine reduction by sodium in ethanol:
A. Pyrrole
B. *Piperazine
C. Pyrimidine
D. Pyridazine
E. Pyridine
446.
Choose systematic name of phenothiazine:
A. Dibenzo-1,4-thiophene
B. Benzo-2-thiazole
C. Benzo-1-thiazole
D. *Dibenzo-1,4-thiazine
E. Dibenzo-1,5-thiazine
447.
What products will form after the phenothiazine interaction with iodomethane?
A. 7-methyl derivatives
B. *N-methyl derivatives
C. S-methyl derivatives
D. 2-methyl derivatives
E. 5-methyl derivatives
448.
What products will form after the phenothiazine interaction with chloroanhydride of
acetic acid?
A. S-acetyl derivatives
B. S-methyl derivatives
C. N-methyl derivatives
D. *N-acetyl derivatives
E. N-chloroderivatives
449.
Oxidation of phenothiazine goes by:
A. *S atom
B. N atom
C. С2 atom
D. С4 atom
450.
451.
452.
453.
454.
455.
456.
457.
458.
459.
E. С6 atom
Which of the following preparations does include phenothiazine nuclei?
A. Phthivazide
B. Furacylline
C. Cordiamine
D. *Aminazine
E. Vitamin РР
What gas will evaporates after the melting of barbituric acids with NaOH:
A. SO3
B. CO
C. SO2
D. NO2
E. *NH3
After the barbiturates interaction with NaOH solution forms:
A. Black precipitate
B. White precipitate
C. *Mono- and disodium salts
D. NH3
E. Gas CO2
After the adding of an excess of AgNO3 to the barbital sodium salt will form:
A. Gas NH3
B. White precipitate of disilver salt
C. *Yellow precipitate of disilver salt
D. Gas СО
E. Black precipitate of Ag
Barbituric acid can exist in these two forms:
A. Acy- and nitroB. *Oxo- and hydroxyC. Lactim and lactam
D. Cyclo- and oxoE. Keto- and enol
For its physical properties pyrimidine is:
A. Gaseous substance
B. Liquid, insoluble in water
C. A black crystalline substance
D. Yellow liquid
E. *Colorless crystalline substance, easily soluble in water
Pyrimidine molecule in the reactions with mineral acids forming salts of:
A. Complex compounds
B. *With the participation of one nitrogen atom
C. Involving two nitrogen atoms
D. Acidic salts
E. Basic salts
Electronodonor substituents in the pyrimidine nuclei:
A. Promote the passage of the АN reactions
B. Promote the passage of the АЕ reactions
C. *Promote the passage of the SЕ reactions
D. Promote the passage of the SN reactions
E. Promote the passage of the Е reactions
Nitration of the pyrimidine derivative (SЕ) is conducted with the following reagent:
A. *HNO3(conc.), H2SO4(conc.)
B. CH3COONO2
C. HNO3(dil.)
D. NO2, H2SO4(conc.)
E. N2, H2SO4(conc.)
Sulfonation of the pyrimidine derivative (SЕ) is conducted with the following reagent:
A. SO3
B.
C.
D.
E.
*H2SO4 (conc.)
SO2
C6H5SO3H
S
460.
Halogenation of the pyrimidine derivative (SЕ) is conducted with the following reagent:
A. HClO3
B. HBrO
C. *Br2(AlCl3)
D. HBr
E. HCl
461.
Choose the positions in the pyrimidine molecule for SN reactions:
A. 2,5,6
B. 1,4,6
C. *2,4,6
D. 2,3,5
E. 1,2,3
462.
Choose the mechanism of the pyrimidine interaction with NaNH2:
A. АЕ
B. АN
C. Е
D. SE
E. *SN
463.
Reaction of pyrimidine interaction with HNО3 (conc.) in the presence of H2SO4 (conc.)
will go by the following mechanism:
A. АЕ
B. SR
C. SN
D. *SE
E. E
464.
Interaction of pyrimidine derivative with Br2 in the presence of H2SO4 (conc.) will go
by the following mechanism:
A. АЕ
B. SR
C. SN
D. *SE
E. E
465.
Barbiturates - 5,5-disubstituted barbituric acid derivatives show:
A. *Hypnotic and antispasmodic action
B. Analgesic effect
C. Antituberculosis action
D. Expectorant action
E. Hemostatic effect
466.
Barbital - 5,5-disubstituted barbituric acid derivative. R and R’ are:
A. *C2H5, C2H5
B. CH3, CH3
C. C2H5, iso-C5H11
D. CH3, C6H5
E. C6H5, C2H5
467.
Phenobarbital - 5,5-disubstituted barbituric acid derivative. R and R’ are:
A. C2H5, C2H5
B. CH3, CH3
C. C2H5, iso-C5H11
D. CH3, C6H5
E. *C6H5, C2H5
468.
Barbamil - 5,5-disubstituted barbituric acid derivative. R and R’ are:
A. C2H5, C2H5
B. CH3, CH3
469.
470.
471.
472.
473.
474.
475.
476.
477.
C. *C2H5, iso-C5H11
D. CH3, C6H5
E. C6H5, C2H5
To the pyrimidine bases the following compound belongs:
A. Pteridine
B. Guanine
C. Purine
D. *Thymine
E. Adenine
The pyrimidine bases the following compound belongs:
A. Pteridine
B. Guanine
C. Purine
D. *Uracil
E. Adenine
To the pyrimidine bases the following compound belongs:
A. Pteridine
B. Guanine
C. Purine
D. *Cytosine
E. Adenine
Uracil is a part of:
A. Phthalazol
B. *Nucleic acid
C. Aminoacid
D. Barbiturates
E. Norsulfazolum
Thymine is a part of:
A. Phthalazol
B. *Nucleic acid
C. Aminoacid
D. Barbiturates
E. Norsulfazolum
Cytosine is a part of:
A. Phthalazol
B. *Nucleic acid
C. Aminoacid
D. Barbiturates
E. Norsulfazolum
For uracil is characteristic the following type of tautomery:
A. *Lactim-lactam tautomery
B. Acy-nitro tautomery
C. Cyclo-oxo tautomery
D. Keto-enol tautomery
E. Oxo-hydroxy tautomery
For cytosine is characteristic the following type of tautomery:
A. *Lactim-lactam tautomery
B. Acy-nitro tautomery
C. Cyclo-oxo tautomery
D. Keto-enol tautomery
E. Oxo-hydroxy tautomery
For thymine is characteristic the following type of tautomery:
A. *Lactim-lactam tautomery
B. Acy-nitro tautomery
C. Cyclo-oxo tautomery
D. Keto-enol tautomery
E. Oxo-hydroxy tautomery
478.
A.
B.
C.
D.
E.
479.
A.
B.
C.
D.
E.
480.
A.
B.
C.
D.
E.
481.
A.
B.
C.
D.
E.
482.
A.
B.
C.
D.
E.
483.
A.
B.
C.
D.
E.
484.
A.
B.
C.
D.
E.
485.
A.
B.
C.
D.
E.
486.
A.
B.
C.
D.
E.
487.
A.
B.
What compound does include pyrimidine cycle?
Vitamin РР
Vitamin Н
Vitamin С
Vitamin А
*Vitamin В1
Which of the following alkaloids does not have optical activity?
Nicotine
*Caffeine
Anabasine
Lobeline
Quinine
Which of the following alkaloids does not have optical activity?
*Theophylline
Nicotine
Lobeline
Anabasine
Quinine
Which of the following alkaloids does not have optical activity?
Nicotine
Lobeline
Anabasine
Quinine
*Theobromine
Which of the following alkaloids does not have optical activity?
Anabasine
Nicotine
*Papaverine
Quinine
Lobeline
Which of the following alkaloids does not have optical activity?
Lobeline
Nicotine
Anabasine
*Codeine
Quinine
Which of the following alkaloids does not have optical activity?
Nicotine
*Scopolamine
Anabasine
Lobeline
Quinine
Which of the following alkaloids does not have optical activity?
*Cocaine
Anabasine
Nicotine
Quinine
Lobeline
Which of the following alkaloids does not have optical activity?
Quinine
Nicotine
Lobeline
Anabasine
*Reserpine
Which of the following alkaloids does not have optical activity?
Nicotine
Anabasine
C. Quinine
D. *Strychnine
E. Lobeline
488.
Which of the following reagents can be used to show basic properties of alkaloids?
A. NH4OH
B. HNO2
C. *HCl
D. NaOH
E. NaCl
489.
Uric acid belongs to:
A. *Dibasis, triatomic acids
B. Onebasic diatomic acids
C. Tribasic, oneatomic acids
D. Dibasic, diatomic acids
E. Tribasic, triatomic acids
490.
Atropine - belladonna alkaloid. Determine reagent that can be used to identify primary
alcoholic group in the atropine molecule:
A. *K2Cr2O7 (H+)
B. HNO3
C. H2SO4
D. FeCl3
E. Ag(NH3) 2OH
491.
Which of the following heterocycles is the base of uric acid?
A. *Purine
B. Indole
C. Pyrimidine
D. Imidazole
E. Pyridine
492.
Adenine, guanine, xanthine and hypoxantine are purine derivatives. How many and
what heteroatoms are in the primer structure of these compounds?
A. *four nitrogen atoms
B. one nitrogen atom and three oxygen atoms
C. two nitrogen atoms and two oxygen atoms
D. three nitrogen atoms and one oxygen atom
E. nothing
493.
Morphine – alkaloid of isoquinoline and phenanthrene isoquinoline group. At the
interaction with FeCl3 solution gives blue color. This reaction is qualitative on:
A. Primary amino-group
B. *Phenol hydroxyl
C. Aldehyde group
D. Secondary nitrogroup
E. α-diol fragment
494.
A purine nucleus is the main structural fragment of caffeine, theophylline, theobromine,
adenine, guanine and uric acid, which have higher physiological activity. Purine is an aromatic
heterocycle. Determine the number of ?-electrons that take part in the formation of aromatic
system.
A. *10
B. 6
C. 14
D. 18
E. 26
495.
The most used method for alkaloids extraction is the following one:
A. Filtration
B. *Extraction
C. Sublimation
D. Recrystallization
E. Distillation
496.
Extraction in the form of salts is one of the methods of alkaloids elimination. In this case
raw materials are processed by:
A. Hexane
B. Formalin
C. Carbon tetrachloride
D. Chloroform
E. *Water or ethyl alcohol acidified by tartaric acid
497.
Extraction in the form of bases is one of the methods of alkaloids elimination. In this
case raw materials are processed by:
A. Hexane
B. Formalin
C. Carbon tetrachloride
D. Chloroform
E. *Water or ethyl alcohol acidified by tartaric acid
498.
From the following list choose general alkaloid reagent:
A. Frede
B. Lughole
C. Felling
D. *Mayer
E. Selivanov
499.
From the following list choose general alkaloid reagent:
A. Frede
B. Lughole
C. *Zonnenstein
D. Felling
E. Selivanov
500.
From the following list choose general alkaloid reagent:
A. Frede
B. *Berthran
C. Lughole
D. Felling
E. Selivanov
501.
From the following list choose general alkaloid reagent:
A. *Sheibler
B. Lughole
C. Frede
D. Felling
E. Selivanov
502.
From the following list choose general alkaloid reagent:
A. Frede
B. Lughole
C. *Dragendorff
D. Felling
E. Selivanov
503.
From the following list choose general alkaloid reagent:
A. Frede
B. Lughole
C. Selivanov
D. Felling
E. *Wagner-Bushard
504.
From the following list choose specific alkaloid reagent:
A. Felling
B. *Erdman
C. Lughole
D. Selivanov
E. Mayer
505.
From the following list choose specific alkaloid reagent:
A.
B.
C.
D.
E.
Felling
Selivanov
Lughole
*Frede
Mayer
506.
From the following list choose specific alkaloid reagent:
A. *Marky
B. Felling
C. Lughole
D. Selivanov
E. Mayer
507.
From the following list choose specific alkaloid reagent:
A. Felling
B. Mayer
C. Lughole
D. Selivanov
E. *Mandelin
508.
From the following list choose specific alkaloid reagent:
A. Felling
B. Lughole
C. *Sodium nitroprusside
D. Selivanov
E. Mayer
509.
Which of the following alkaloids does belong to pyridine and piperidine group?
A. Quinine
B. *Nicotine
C. Morphine
D. Codeine
E. Atropine
510.
Which of the following alkaloids does belong to pyridine and piperidine group?
A. Isoquinoline
B. Scopolamine
C. Morphine
D. Codeine
E. *Anabasine
511.
Which of the following alkaloids does belong to pyridine and piperidine group?
A. Quinoline
B. Codeine
C. Papaverine
D. *Lobeline
E. Atropine
512.
Which of the following alkaloids does belong to quinoline group?
A. *Quinine
B. Nicotine
C. Morphine
D. Codeine
E. Atropine
513.
Which of the following alkaloids does belong to isoquinoline and phenenthrene
isoquinoline group?
A. Nicotine
B. Scopolamine
C. Quinine
D. *Papaverine
E. Anabasine
514.
Which of the following alkaloids does belong to isoquinoline and phenenthrene
isoquinoline group?
A. Nicotine
B.
C.
D.
E.
*Morphine
Quinine
Lobeline
Anabasine
515.
Which of the following alkaloids does belong to isoquinoline and phenenthrene
isoquinoline group?
A. Atropine
B. Papavarine
C. *Codeine
D. Quinine
E. Anabasine
516.
Which of the following alkaloids does belong to tropane group?
A. *Atropine
B. Nicotine
C. Papaverine
D. Quinine
E. Morphine
517.
Which of the following alkaloids does belong to tropane group?
A. Nicotine
B. *Scopolamine
C. Codeine
D. Quinine
E. Morphine
518.
Which of the following alkaloids does belong to tropane group?
A. Papaverine
B. Lobeline
C. *Cocaine
D. Quinine
E. Morphine
519.
Which of the following alkaloids does belong to indole group?
A. Quinine
B. *Reserpine
C. Nicotine
D. Morphine
E. Cocaine
520.
Which of the following alkaloids does belong to indole group?
A. Codeine
B. Cocaine
C. Nicotine
D. Morphine
E. *Strychnine
521.
To which group of alkaloids does theophylline belong?
A. Indole
B. Tropane
C. *Purine
D. Quinoline
E. Pyridine and piperidine
522.
To which group of alkaloids does theobromine belong?
A. Indole
B. Phenanthrene isoquinoline
C. Quinoline
D. *Purine
E. Pyridine and piperidine
523.
To which group of alkaloids does caffeine belong?
A. Pyridine and piperidine
B. Indole
C. Isoquinoline
524.
525.
526.
527.
528.
529.
530.
531.
532.
533.
D. Quinoline
E. *Purine
To which group of alkaloids does nicotine belong?
A. *Pyridine and piperidine
B. Tropane
C. Purine
D. Quinoline
E. Indole
To which group of alkaloids does anabasine belong?
A. Phenanthrene
B. Tropane
C. Purine
D. *Pyridine and piperidine
E. Quinoline
To which group of alkaloids does lobeline belong?
A. Indole
B. *Pyridine and piperidine
C. Piperidine
D. Isoquinoline
E. Pyridine
To which group of alkaloids does quinine belong?
A. Isoquinoline
B. Tropane
C. Purine
D. *Quinoline
E. Pyridine and piperidine
To which group of alkaloids does papaverine belong?
A. *Isoquinoline and phenanthrene isoquinoline
B. Quinoline
C. Tropane
D. Indole
E. Purine
To which group of alkaloids does morphine belong?
A. Isoquinoline
B. Quinoline
C. *Isoquinoline and phenanthrene isoquinoline
D. Indole
E. Phenanthrene
To which group of alkaloids does codeine belong?
A. Purine
B. Pyridine and piperidine
C. Indole
D. Tropane
E. *Isoquinoline and phenanthrene isoquinoline
To which group of alkaloids does atropine belong?
A. Isoquinoline and phenanthrene isoquinoline
B. Quinoline
C. *Tropane
D. Indole
E. Purine
To which group of alkaloids does scopolamine belong?
A. Phenanthrene isoquinoline
B. Quinoline
C. Isoquinoline
D. *Tropane
E. Indole
To which group of alkaloids does cocaine belong?
A.
B.
C.
D.
E.
Purine
*Tropane
Isoquinoline
Indole
Quinoline
534.
To which group of alkaloids does reserpine belong?
A. Isoquinoline and phenanthrene isoquinoline
B. Quinoline
C. Tropane
D. *Indole
E. Purine
535.
To which group of alkaloids does strychnine belong?
A. Tropane
B. Quinoline
C. *Indole;
D. Isoquinoline
E. Putine
536.
Nicotine – alkaloid of pyridine and piperidine group in the little amount nicotine has:
A. Spasmolytic action
B. *Arousing effect on the autonomic system
C. Antituberculosis action
D. Antipyretic action
E. Analgesic action
537.
Nicotine, being a poisonous substance is used as:
A. Flavor
B. Stain
C. Bleach
D. Solvent
E. *Insecticide
538.
Anabasine – alkaloid of pyridine and piperidine group. Anabasine is used in the
medicine as:
A. *Mean against smoking
B. Antituberculosis mean
C. Expectorant mean
D. Spasmolytic mean
E. Sedative mean
539.
Quinine – alkaloid of quinoline group. Quinine is used in the medicine as:
A. *Antimalarial remedy
B. Antituberculosis mean
C. Expectorant mean
D. Spasmolytic mean
E. Sedative mean
540.
Papaverine – alkaloid of quinoline and phenanthrene isoquinoline group. Papaverine is
used in the medicine:
A. Antimalarial remedy
B. Antituberculosis mean
C. Expectorant mean
D. *Spasmolytic mean
E. Sedative mean
541.
What is the name of the following terpene?
A.
B.
C.
D.
E.
α-pinene
squalene
limonene
*ocimene
myrcene
What is the name of the following terpene compound?
A.
B.
C.
D.
E.
camfora
squalene
*limonene
ocimene
myrcene
Choose the product of β-lactose interaction with excess of acetic anhydride
542.
543.
A.
B.
C.
D.
544.
E. *
What is the name of the following terpenoid?
A.
B.
C.
D.
E.
menthol
*α-terpineol
farnesol
nerol
geraniol
Which group of compounds does menthol belong?
A.
B.
C.
D.
E.
*diene aldehyde
diene alcohol
alicyclic aldehyde
bicyclic alcohol
monocyclic aldehyde
Which group of compounds does menthol belong?
A.
B.
C.
D.
E.
bicyclic ketone
aliphatic alcohol
cycloalkane
*monocyclic alcohol
bicyclic alcohol
Which group of compounds does squalene belong?
545.
546.
547.
A.
B.
C.
D.
E.
monocyclic alkane
monocyclic alcohol
bicyclic alkane
*polyene
bicylic aldehyde
Which group of compounds does farnesol belong?
A.
B.
C.
D.
E.
saturated alcohol
bicyclic ketone
*polyene alcohol
monocyclic alcohol
bicyclic alcohol
Choose the product of the following reaction?
A.
B.
C.
D.
E.
camphene
terpin hydrate
terpin
α-pinene
*borneol
What is the name of the following terpene?
548.
549.
550.
A.
B.
C.
D.
E.
551.
α-pinene
squalene
limonene
ocimene
*myrcene
What is the product of primary oxidation of camphor with nitric acid?
A.
B.
C.
D. *
E.
552.
What is the product of nerol cyclization in acidic media?
A.
B.
C. *
D.
E.
553.
Choose the number of chiral atom in the molecule of ¥á-terpineol.
A.
B.
C.
D.
E.
554.
5
*4
3
2
1
Choose the number of chiral atom in the molecule of limonene.
A. 5
B. *4
555.
C. 3
D. 2
E. 1
Which group of compounds does geraniol belong?
A.
B.
C.
D.
E.
bicyclic diene
aliphatic alcohol
diene alcohol
*diene alcohol
diene aldehyde
Which group of compounds does myrcene belong?
A.
B.
C.
D.
E.
cycloalkane
bicyclic aldehyde
monocyclic aldehyde
*aliphatic polyene
aliphatic alcohol
Which of the following reagents can be used to distinguish phenylalanine from tyrosine?
556.
557.
A.
B.
C.
D. *
E.
558.
A.
B.
C.
D.
E.
559.
Choose the correct definition of nucleotide.
*nucleotide is the phosphoric acid ester of nucleoside
nucleotide is N-glycoside, which consist of nucleobase and D-ribose
nucleotide is the phosphoric acid ester of pyrimidine nucleobase
nucleotide is the phosphoric acid ester of purine nucleobase
nucleotide is the compound which consist of carbohydrate and heterocyclic nucleobase
What is the product of α-amino acids reaction with nitrous
acid
?
A.
B.
C. *
D.
E.
560.
Choose the systematic name of α-cellobiose.
A.
B.
C.
D. *
E.
561.
Choose the name of the following disaccharide.
A. *
B.
C.
D.
E.
562.
A.
B.
C.
D.
E.
563.
How many chiral carbon atomes does β-D-fructofuranose have?
three
three
five
*four
one
Choose the product of D-glucose reduction.
A.
B.
C. *
D.
E.
564.
How many asymmetric carbon atoms does β-D-glucopyranose have?
A.
B.
C.
D.
E.
six
*four
five
one
three
565.
Among the peptides listed below choose the one with peptide sequence: alanine,
glutamine and glycine (Ala-Glu-Gly).
A.
B.
C.
D. *
E.
566.
Among the peptides listed below choose the one with peptide sequence: glutamic acid,
glycine and alanine (Glu-Gly-Ala).
A. *
B.
C.
D.
E.
567.
What is the name of the following terpenoid?
A.
B.
C.
D.
E.
*α-pinene
squalene
limonene
ocimene
myrcene
What is the name of the following terpenoid?
A.
B.
C.
D.
E.
menthol
α-terpineol
farnesol
*nerol
geraniol
What is the name of the following terpenoid?
A.
B.
C.
D.
E.
*menthol
α-terpineol
farnesol
nerol
Geraniol
What is the name of the following terpenoid?
568.
569.
570.
A.
B.
C.
D.
E.
menthol
α-terpineol
farnesol
nerol
*geraniol
What is the name of the following terpenoid?
A.
B.
C.
D.
E.
menthol
α-terpineol
*farnesol
nerol
geraniol
Which of the following reagents can be applied to obtain acyl halide from alanine?
571.
572.
A.
B.
C.
D.
573.
E. *
Choose the name of the following disaccharide.
A.
B.
C.
D. *
E.
574.
Choose the systematic name of β-maltose.
A. *
B.
C.
D.
E.
575.
Choose the name of the following disaccharide.
A.
B.
C.
D.
E.
576.
A.
B.
C.
D.
E.
577.
β- maltose
*β-cellobiose
β- lactose
sucrose
α- maltose
Which of the following disaccharides gives galactose and glucose after hydrolysis?
mannose
cellobiose
*lactose
maltose
sucrose
Choose the systematic name of beta-cellobiose.
A.
B.
C.
D. *
E.
578.
Choose the systematic name of α-maltose.
A.
B.
C. *
D.
E.
579.
A.
B.
C.
D.
E.
580.
A.
B.
C.
D.
E.
deoxymonosaccharide
aldohexose
ketohexose
*ketopentose
aldopentose
What is the name of the following monosaccharide?
A.
B.
C.
D.
E.
D–xylose
D–galactose
*D–glucose
D–mannose
D–fructose
What is the name of the following monosaccharide?
581.
582.
The change of the specific rotation of sucrose solution caused by its hydrolysis is called:
in all possible tautomeric forms
*inversion
mutorotation
isomerization
epimerization
The following monosaccharide belongs to:
A.
B.
C.
D.
E.
583.
A.
B.
C.
D.
E.
584.
A.
B.
C.
D.
E.
585.
*L– mannose
L– galactose
D–galactose
L– glucose
D–glucose
Choose the correct definition for protein denaturation.
*destruction of the protein form, with retention of primary structure of protein
destruction of quaternary structure, with retention of primary secondary and tertiary structures
of protein
destruction of tertiary structure, with retention of primary and secondary structures of protein
destruction of secondary structure, with retention of primary structure of protein
destruction of primary structure of protein
What are the products of nucleic acids complete hydrolysis?
*nucleobases, monosaccharides and phosphoric acid
nucleobases, monosaccharides and water
glycosides and phosphoric acid
nucleosides and phosphoric acid
nucleotides
What is the product of glycine reaction with ethanol?
A.
B. *
C.
D.
E.
586.
Choose the cationic form of amino acids.
A.
B.
C. *
D.
E.
587.
Choose the product of borneol oxidation.
A.
B. *
C.
D.
E.
588.
Choose the systematic name of β-lactose.
A.
B.
C.
D.
589.
590.
591.
E. *
What are the products of glucose oxidation with Fehling’s reagent?
A. *mixture of oxidation products + Cu2O
B. glucaric acid + CuO
C. gluconic acid + Cu
D. glucuronic acid + Cu2O
E. sorbitol + CO2
Which is the correct definition of epimeric monosaccharides?
A. monoses, which have the different configuration of all chiral carbon atoms
B. monoses, which have the different configuration of four chiral carbon atoms
C. monoses, which have the different configuration of three chiral carbon atoms
D. *monoses, which have the different configuration of one chiral carbon atom
E. monoses, which have the different configuration of two chiral carbon atoms
What is the name of the following monosaccharide?
A.
B.
C.
D.
E.
592.
*D–mannose
L– galactose
D–galactose
L– glucose
D–glucose
What is the name of the following monosaccharide?
A.
B.
C.
D.
E.
593.
L–galactose
D–xylose
*D–ribose
L–arabinose
D–arabinose
Choose the correct systematic name of α -lactose.
A.
B.
C.
D.
594.
E. *
Amylose (water-soluble fraction of starch) is planar polymer which consists of:
A.
B.
C. *
D.
E.
595.
A.
B.
C.
D.
E.
596.
A.
B.
C.
D.
E.
597.
Choose the correct complementary pair of nucleobases among the listed below.
hypoxanthine - cytosine
thymine - uracil
uracil - hypoxanthine
*adenine - thymine
guanine - uracil
Which group of compounds does camphor belong?
cycloalkanol
aliphatic alcohol
bicyclic alkene
*bicyclic ketone
aliphatic ketone
Which group of compounds does limonene belong?
A.
B.
C.
D.
E.
cyclopolyene
bicyclic aldehyde
cycloalkane
aliphatic ketone
*monocyclic diene
598.
Terpenes are unsaturated compounds with the formula (C5H8)n, where n - number of
isoprene fragments. What is the name of terpenes type with п = 8?
A. *tetraterpenes
B. triterpenes
C. diterpenes
D. sesquiterpenes
E. monoterpenes
599.
Terpenes are unsaturated compounds with the formula (C5H8)n, where n - number of
isoprene fragments. What is the name of terpenes type with п = 6?
A. tetraterpenes
B. *triterpenes
C. diterpenes
D. sesquiterpenes
E. monoterpenes
600.
To which group of lipids do terpenes belong?
A. phospholipids
B. waxes
C. fats
D. *isoprenoids
E. prostaglandins
601.
Which group of compounds does borneol belong?
A.
B.
C.
D.
E.
602.
cycloalkane
*bicyclic alcohol
polycyclic polyene
bicyclic ketone
aliphatic alcohol
Which group of compounds does α-pinene belong?
A. *bicyclic alkene
B. bicycles polyene
C. bicyclic alkyne
D. aromatic hydrocarbon
E. monocyclic alkene
603.
Terpenes are unsaturated compounds with the formula (C5H8)n, where n - number of
isoprene fragments. What is the name of terpenes type with п = 4?
A. tetraterpenes
B. triterpenes
C. *diterpenes
D. sesquiterpenes
E. monoterpenes
604.
Terpenes are unsaturated compounds with the formula (C5H8)n, where n - number of
isoprene fragments. What is the name of terpenes type with п = 3?
A. tetraterpenes
B. triterpenes
C. diterpenes
D. *sesquiterpenes
E. monoterpenes
605.
Terpenes are unsaturated compounds with the formula (C5H8)n, where n - number of
isoprene fragments. What is the name of terpenes type with n = 2?
A. tetraterpenes
B. triterpenes
C. diterpenes
D. sesquiterpenes
E. *monoterpenes
606.
Choose the correct reaction scheme of oxyproline with hydrochloric acid.
A.
B. *
C.
D.
E.
607.
Choose the correct reaction scheme of histidine with iodo methane.
A.
B.
C. *
D.
E.
608.
A.
B.
C.
D.
E.
609.
Which monosaccharide is the part of RNA?
arabinose
fructose
glucose
deoxyribose
*ribose
What are the products of adenosinemonophosphoric acid complete hydrolysis?
A.
B.
C.
D.
E.
610.
three molecules of phosphoric acid and adenine
two molecules of phosphoric acid, deoxyribose and adenine
*one molecule of phosphoric acid, ribose and adenine
one molecule of phosphoric acid and adenine
two molecules of phosphoric acid and adenine
Choose peptide-group among the listed below.
A.
B. *
C.
D.
E.
611.
A.
B.
C.
D.
E.
612.
A.
Which bond is used for construction of primary structure of protein?
coordinative
semi polar
*peptide
ionic
hydrogen
Which of the following reaction occurs on the aryl moiety of phenylalanine molecule?
B. *
C.
D.
E.
613.
A.
B.
C.
D.
E.
614.
Which of the following monosaccharides is the part of DNA?
mannose
ribose
glucose
*deoxyribose
fructose
Choose the acidic amino acids among the listed below.
A.
B. *
C.
D.
E.
615.
A.
B.
C.
D.
E.
616.
The bond of which type plays the essential role in the nucleobase pairing?
semi polar bond
ionic bond
hydrophobic interactions
*hydrogen bond
non-polar covalent bond
Which of the following acids forms γ-lactame of the structure listed below?
A.
B.
C.
D.
E.
617.
5– aminohexanoic acid
3–aminopropanoic acid
5– aminohexanoic acid
*4-aminobutanoic acid
4–aminohexanoic acid
Which of the following amino acids will form crotonic acid when heated?
A.
B.
C. *beta-aminobutyric acid
D. γ-glutamic acid amide (glutamine)
E.
618.
Choose the amino acid which forms the 3,6-dimethyl-2,5-dioxopiperazine when heated.
A.
B.
C.
D.
619.
E. *
Which of the following reactions can be used for quantitative analyses of α-amino acids?
A.
B.
C.
D.
E. *
620.
With which of the following reagents 3-aminobutanoic acid will undergo dezamination
reaction?
A.
B.
C. *
D.
E.
621.
Choose the reaction of oxidative dezamination which proceeds in the human body.
A.
B.
C. *
D.
E.
622.
Choose the correct scheme of α-aminoisovaleric acid (valine) transformation:
A. *
B.
C.
D.
E.
623.
Which bond plays the essential role in formation of spiral secondary structure of
proteins?
A. hydrophobic interactions
B. semipolar
C. peptide
D. ionic
E. *hydrogen
624.
Among the listed below choose α-amino acids.
A.
B.
C. *
D.
E.
625.
Choose the structure of ascorbic acid (vitamin C):
A.
B.
C.
D. *
E.
626.
The interaction of cellulose with excess of acetanhydride in the presence of H2SO4
(catalyst) leads to formation of:
A. cellulose sulfate
B. *cellulose triacetate
C. cellulose xanthogenate
D. cellulose diacetate
E. cellulose acetate
627.
What is the product of reaction of cellulose with excess mixture of nitric and sulfuric
acids?
A. cellulose disulfate
B. *cellulose trinitrate (pyroxiline)
C. cellulose sulfate
D. cellulose dinitrate
E. cellulose mononitrate
628.
Choose the name of the following disaccharide.
A.
B.
C. *
D.
E.
629.
Choose the product of interaction of β-cellobiose with excess of ¬³¬¯3І.
A.
B.
C. *
D.
E.
630.
A.
B.
C.
D.
E.
Which is the end-product of acidic hydrolysis of cellulose?
α-lactose
β-maltose
D-fructofuranose
*D-glucopyranose
D- galactopyranose
631.
Starch consists of amylose and amylopectine which can be hydrolyzed by enzymes to Dglucose. Choose the correct scheme of starch hydrolysis.
A.
B. *
C.
D.
E.
632.
What is the systematic name of sucrose?
A.
B. *
C.
D.
E.
633.
What does symbol «D» in the name of D-(+)glucose means?
A.
B.
C.
D.
E.
634.
*the relative configuration of C5 atom
the relative configuration of C4 atom
the relative configuration of C2 atom
levorotatory isomer
dextrorotatory isomer
D-Glucose in the sodium hydroxide solution in the course of time forms the mixture of
D-glucose, D-mannose and D-fructose. What is the name of these transformations?
A. Walden inversion
B. anomerization
C. cyclization
D. *epimerization
E. mutarotation
635.
Amylopectine (the insoluble in water fraction of starch) is the branched polymer, which
consists of:
A.
B.
C. *
D.
E.
636.
Choose the structure of alfa -D-galactopyranose?
A.
B.
C. *
D.
E.
637.
Which of the following reagents will form osazones with monosaccharides?
A. semicarbazide
B. hydrazine
C. *phenylhydrazine
638.
D. hydroxylamine
E. ammonia
What does the symbol “-“ in the name L-(-)-glucose means?
the relative configuration of С2 atom
the relative configuration of С5 atom
dextrorotatory isomer
*levorotatory isomer
the relative configuration of С4 atom
639.
When D-glucose is treated with sodium hydroxide solution for a few days it forms the
mixture of:
A. D– glucose, D– galactose and D– fructose
B. D– glucose, D–galactose and D– mannose
C. *D– glucose, D– mannose and D– fructose
D. D–glucose and D–mannose
E. D–glucose and D–fructose
640.
What is the product of D-fructose oxidation with nitric acid?
A. D–galacturonic acid
B. *D–arabinaric acid
C. D–mannitol
D. D–glucaric acid
E. D–gluconic acid
641.
In the crystals the molecules of monosaccharides are in the:
A. enolic hydroxyl
B. endiol form
C. in all possible tautomeric forms
D. acyclic form
E. *cyclic form
642.
Choose the structure of β-D-galactopyranose?
A.
B.
C.
D.
E.
A.
B.
C. *
D.
E.
643.
Choose the structure of β-D-ribofuranose?
A.
B.
C.
D.
644.
E. *
D-glucose and D-mannose are epimers because:
A.
B.
C.
D.
E.
645.
have?
have the different configuration of the fifth carbon atom
are the members of the same stereochemical range
have the different number of chiral carbon atoms
*have the different configuration of the second carbon atom
have the equal number of chiral carbon atoms
How many asymmetric carbon atoms (chiral C atoms) does the following monosacharide
A.
B.
C.
D.
E.
five
four
*two
three
one
How many stereoisomers does the following aldohexose have?
A.
B.
C.
D.
E.
eight
thirty two
*sixteen
four
eight
The mutarotation is caused by:
have the equal number of chiral carbon atoms
inversion of configuration of the cyclic forms of monosacharides
*equilibrium of tautomeric forms conversion in the solution
epimeric transformations of monosaccharides
inversion of configuration of the last carbon atom
Which of the following monosccharides are hexoses?
galactose
ribose
arabinose
*mannose
xylose
The change of specific rotation of monosaccharides solution in the course of time is
646.
647.
A.
B.
C.
D.
E.
648.
A.
B.
C.
D.
E.
649.
called:
A. enolic hydroxyl
B. epimerization
C. *mutarotation
D. isomerization
650.
E. inversion
How many stereoisomers does the following aldopentose have?
A. ten
B. *
C.
D.
E.
651.
Glucose can react in the open and cyclic form. Glucose interacts with: 1)Br2 (H2O); 2)
HNO3; 3) (CH3CO)2O; 4) [Ag(NH3)2]OH; 5)CH3OH (HCl). Which of the following reactions
does glucose give in the cyclic form?
A. *3, 5
B. 1, 3
C. 3, 4
D. 2, 5
E. 1, 2
652.
Which isomers of monosaccharides are called anomers? Choose the correct definition.
A. the cyclic forms of mannoses that differ only in their configuration at the С3
B. the cyclic forms of mannoses that differ only in their configuration at the С2 and С3
C. *the cyclic forms of mannoses that differ only by the position of hemiacetal hydroxyl
D. the cyclic forms of mannoses that differ only in their configuration at the С2
E. the cyclic forms of mannoses that differ only in their configuration at the С5
653.
The change of the specific rotation of the freshly prepared monosaccharides solution is
called:
A. inversion
B. isomerization
C. tautomery
D. epimeryzation
E. *mutarotation
654.
Which of the following monosaccharides does belong to hexoses?
A. xylose
B. *mannose
C. arabinose
D. ribose
E. lyxose
655.
Which of the following monosaccharides does belong to hexoses?
A. xylose
B. ribose
C. arabinose
D. *glucose
E. lyxose
656.
Which of the following monosaccharides does belong to hexoses?
A. *galactose
B. xylose
657.
658.
659.
660.
661.
662.
663.
664.
665.
C. arabinose
D. ribose
E. lyxose
Which of the following monosaccharides does belong to hexoses?
A. xylose
B. lyxose
C. arabinose
D. ribose
E. *fructose
Which of the following monosaccharides does belong to pentoses?
A. *xylose
B. mannose
C. glucose
D. fructose
E. galactose
Which of the following monosaccharides does belong to pentoses?
A. glucose
B. mannose
C. *arabinose
D. fructose
E. galactose
Which of the following monosaccharides does belong to pentoses?
A. glucose
B. mannose
C. galactose
D. *ribose
E. fructose
Which of the following monosaccharides does belong to pentoses?
A. fructose
B. mannose
C. galactose
D. glucose
E. *lyxose
Which of the following monosaccharides does belong to ketoses?
A. xylose
B. mannose
C. *fructose
D. ribose
E. arabinose
Which of the following monosaccharides does belong to ketohexoses?
A. xylose
B. mannose
C. *fructose
D. ribose
E. lyxose
Which of the following monosaccharides does belong to aldohexoses?
A. xylose
B. ribose
C. fructose
D. *mannose
E. arabinose
Which of the following monosaccharides does belong to aldohexoses?
A. xylose
B. *glucose
C. fructose
D. ribose
E. arabinose
666.
Which of the following monosaccharides does belong to aldohexoses?
A. xylose
B. arabinose
C. fructose
D. ribose
E. *galactose
667.
Which of the following monosaccharides does belong to aldopentoses?
A. *xylose
B. mannose
C. fructose
D. galactose
E. glucose
668.
Which of the following monosaccharides does belong to aldopentoses?
A. fructose
B. mannose
C. *ribose
D. galactose
E. glucose
669.
Which of the following monosaccharides does belong to aldopentoses?
A. galactose
B. mannose
C. fructose
D. *arabinose
E. glucose
670.
Cyclic forms of monosaccharides in the chemical condition are:
A. cyclic ethers
B. *cyclic hemiacetals
C. cyclic esters
D. anhydrides
E. cyclic hemiketals
671.
The mutarotation is cased by:
A. the change of the configuration at the last asymmetric carbon atom
B. epimeric transformations of the monosaccharides
C. *mutual transformations of the monosaccharides formf in the solution and achievement of the
equilibrium between them
D. the change of the monosaccharides cyclic forms configuration
E. the change of the configuration at the С4
672.
The hydroxyl-group, which is formed by monosaccharides cyclization is called:
A. *hemiacetal hydroxyl
B. epimeric hydroxyl
C. anomeric hydroxyl
D. hemiketal hydroxyl
E. enolic hydroxyl
673.
The hydroxygroup, which is formed by monosaccharides cyclization is called:
A. epimeric hydroxyl
B. *glycosidic hydroxyl
C. anomeric hydroxyl
D. hemiketal hydroxyl
E. enolic hydroxyl
674.
D-glucose and D-mannose are epimers, because:
A. have an equal number of chiral carbon atoms
B. have the different configuration of the fifth carbon atom
C. have the different number of the chirality centers
D. are the members of the same stereochemical range
E. *have the different configuration of the second carbon atom
675.
Phenomenon, which is cased by the change of the sucrose solution specific optical
rotation during the hydrolysis, is called:
A.
B.
C.
D.
E.
epimerization
isomerization
*mutarotation
inversion
tautomery
676.
Monosaccharides in the crystalline state have:
A. cyclic struscture
B. alicyclic structure
C. epimeric forms
D. endiol structure
E. *structure that includes all tautomeric forms
677.
Determine compound, which will form after the oxidation of D–fructose by concentrated
nitrate acid:
A. D–gluconic acid
B. D–glucaric acid
C. D–mannite
D. *D–arabinaric acid
E. D–galacturonic acid
678.
Determine compound, which will form after the oxidation of D–glucose by concentrated
nitrate acid:
A. D–gluconic acid
B. *D–glucaric acid
C. D–mannite
D. D–arabinaric acid
E. D–galacturonic acid
679.
Determine compound, which will form after the oxidation of D–mannose by
concentrated nitrate acid:
A. D–gluconic acid
B. *D–mannaric acid
C. D–mannite
D. D–arabinaric acid
E. D–galacturonic acid
680.
Determine compound, which will form after the oxidation of D–galactose by
concentrated nitrate acid:
A. D–gluconic acid
B. *D–glucaric acid
C. D–mannite
D. D–galactaric acid
E. D–galacturonic acid
681.
Determine compound, which will form after the D–galactose oxidation by bromine
water:
A. *D–galactonic acid
B. D–glucaric
C. D–mannite
D. D–galactaric acid
E. D–galacturonic
682.
Determine compound, which will form after the D–glucose oxidation by bromine water:
A. D–mannite
B. D–glucaric acid
C. *D–gluconic acid
D. D–galactaric acid
E. D–galacturonic acid
683.
Determine compound, which will form after the D–mannose oxidation by bromine
water:
A. D–gluconic acid
B. D–glucaric acid
C. D–mannite
D. *D–mannonic acid
E. D–galacturonic acid
684.
Determine compound, which will form after the oxidation of D–ribose by concentrated
nitrate acid:
A. D–gluconic acid
B. D–glucaric acid
C. D–ribonic acid
D. *D–ribaric acid
E. D–galacturonic acid
685.
Determine compound, which will form after the oxidation of D–ribose by bromine
water:
A. D–gluconic acid
B. D–glucaric acid
C. *D–ribonic acid
D. D–ribaric acid
E. D–galacturonic acid
686.
Which isomers of monosaccharides are called epimers?
A. hexoses that are different by the configuration of two asymmetric carbon atoms
B. *hexoses that are different by the configuration of one asymmetric carbon atoms
C. hexoses that are different by the configuration of three asymmetric carbon atoms
D. hexoses that are different by the configuration of all asymmetric carbon atoms
E. hexoses that are different by the configuration of four asymmetric carbon atoms
687.
What reaction do monosaccharides in the cyclic form?
A. *alkylation
B. epimeryzation
C. reduction
D. ozazones formation
E. hydrazides formation
688.
Determine what compound will form after the glucose oxidation by Felling reagent:
A. sorbite + CO2
B. glucuronic acid + Cu2O
C. gluconic acid + Cu
D. glucaric acid + CuO
E. *mixture of the oxidation products + Cu2O
689.
D–glucose in the sodium hydroxide solution during few days forms the mixture of
monosaccharides, which consists of:
A. D–glucose and D–fructose
B. D–glucose and D–mannose
C. *D–glucose, D–mannose and D–fructose
D. D–glucose, D–galactose and D–mannose
E. D–glucose, D–galactose and D–fructose
690.
Choose the reagent that can oxidize aldoses:
A. hydrochloric acid
B. acetic acid
C. phenylhydrazine
D. *bromine water
E. sodium hydroxide alcoholic solution
691.
Choose the reagent that can oxidize aldoses:
A. hydrochloric acid
B. *nitrate acid
C. phenyl hydrazine
D. acetic acid
E. sodium hydroxide alcoholic solution
692.
Which of the following reactions, characteristic for aldehydes, do monosaccharides give?
A. formation of hydrosulfite derivatives
B. formation of ethers
C. formation of esters
D. *formation of phenyl hydrazones
E. interaction with fuchsine sulfite acid
693.
What disaccharide will give reaction with Tollens reagent?
A. sucrose
B. maltose
C. amylose
D. amylopectin
E. *cellulose
694.
Choose the end product of the cellulose hydrolysis, which will form after its heating with
mineral acids:
A. D-galactopyranose
B. *D-glucopyranose
C. D-fructofuranose
D. D-maltose
E. E-lactose
695.
What reagents can be used to distinguish maltose and sucrose?
A. *Tollens reagent
B. Reaction with α-naphthalene
C. Felling liquid
D. Fuchsine sulfite acid
E. Trommer test
696.
What product will form after the adding of an excess of nitric mixture to cellulose?
A. cellulose mononitrate
B. cellulose dinitrate
C. cellulose sulfate
D. *cellulose trinitrate (pyroxylin)
E. cellulose disulfate
697.
What product will form after the cellulose interaction with acetic anhydride at the
presence of conc. H2SO4 (catalyst)?
A. cellulose acetate
B. cellulose diacetate
C. cellulose xanthogenate
D. *cellulose triacetate
E. cellulose sulfate
698.
What monosaccharide is a product of starch hydrolysis?
A. *glucose
B. fructose
C. mannose
D. ribose
E. galactose
699.
To the heteropolysaccharides the following compound belongs:
A. starch
B. cellulose
C. methyl-D-galactopyranoside
D. deoxyribose
E. *chondroitin sulfate
700.
Nonreducing disaccharide is the following one:
A. cellobiose
B. maltose
C. *sucrose
D. lactose
E. xylose
701.
Which of the following polysaccharides is used in the pharmacy in the production of
“polyglucin’ and “rheopolyglucin”?
A. *dextrans
B. dextrins
C. cellulose
D. pectines
E. inulin
702.
Sucrose, maltose and lactose are disaccharides. They found wide application in the food
industry and medicine. With which of the proposed reagents can be identified among of these
disaccharides reducing and nonreducing?
A. H2SO4
B. NaOH
C. K2CO3
D. *[Ag(NH3)2]OH
E. CH3COOH
703.
Disaccharide form by hydrolysis of polysaccharides. What disaccharide will form after
the hydrolysis of starch?
A. pyrogalose
B. lactose
C. cellobiose
D. sucrose
E. *maltose
704.
Cellulose belongs to the polysaccharides. Choose monosaccharide, which will form after
the cellulose hydrolysis:
A. β- D -fructopyranose
B. α- D -glucopyranose
C. *β- D -glucopyranose
D. α- D -fructofuranose
E. β- D -glucofuranose
705.
Which of the following sugars does not form brick-red precipitate after the heating with
Felling reagent?
A. *sucrose
B. glucose
C. lactose
D. cellulose
E. mannose
706.
Fraction of starch is:
A. cellulose
B. maltose
C. fructose
D. *amylose
E. glycogen
707.
Choose monosaccharides that are structural elements of sucrose:
A. only glucose
B. *glucose, fructose
C. glucose, galactose
D. only fructose
E. fructose, mannose
708.
Which of the following disaccharides will not react with Felling reagent?
A. lactose and maltose
B. lactose
C. maltose
D. cellobiose
E. *sucrose
709.
Disaccharides form by hydrolysis of polysaccharides. What disaccharide will form after
the cellulose hydrolysis?
A. lactose
B. maltose
C. *cellobiose
D. sucrose
E. pyrogalose
710.
From the following compounds choose reducing disaccharide:
A.
B.
C.
D.
E.
711.
A.
B.
C.
D.
E.
712.
A.
B.
C.
D.
E.
713.
A.
B.
C.
D.
E.
714.
A.
B.
C.
D.
E.
715.
A.
B.
C.
D.
E.
716.
A.
B.
C.
D.
E.
717.
A.
B.
C.
D.
E.
718.
A.
B.
C.
D.
E.
719.
A.
B.
C.
inulin
*lactose
stachyose
sucrose
fructose
Choose chemical name of lactose:
*β–D–galactosido–1,4–?–D–glucopyranose
β–D–fructofuranose
α–D–glucopyranosido–1,2–?–D–fructofuranose
α–D–glucopyranosido–1,4–?– D–dlucopyranose
β–D–glucopyranosido–1,4–?– D–glucopyranose
Choose chemical name of maltose:
β–D–galactose–1,4–?–D–glucopyranose
β–D–galactosido–1,4–?–D–fructofuranose
α–D–– glucopyranosido-1,2–?–D–fructofuranose
*α–D– glucopyranosido –1,4–?–D–glucopyranose
β–D-glucopyranosido –1,4–?–D–glucopyranosido
Choose chemical name of sucrose:
β–D–galactosido–1,4–?–D–glucopyranose
2-β–D–fructofuranose
*α–D–glucopyranosido–1,2–?–D–fructofuranose
α–D––glucopyranosido-1,4–?– D–glucopyranose
β–D–glucopyranosido –1,4–?– D–glucopyranose
Choose chemical name of cellobiose:
β–D–galactosido–1,4–?–D–glucopyranose
β–D–fructofuranose;
α–D–glucopyranosido–?–D–fructofuranose
α–D–glucopyranosido–1,4–?– D–glucopyranose
*β–D– glucopyranosido–1,4–?– D–glucopyranose
At the disaccharides hydrolysis the following compounds form:
esters
carboxylic acids and water
polysaccharides
1 molecule of Carbon (IV) oxide and water
*2 molecules of monosaccharides
At the lactose hydrolysis the following compounds form:
α-glucose and β-fructose
*β-galactose and α-glucose
2 molecules of β-glucose
2 molecules of β-galactose
2 molecules of α-glucose
At the maltose hydrolysis the following compounds will form:
α-glucose and β-fructose
β-galactose and α-glucose
2 molecules of β-glucose
2 molecules of β-galactose
*2 molecules of α-glucose
At the cellulose hydrolysis the following compounds will form:
α-glucose and β-fructose
β-galactose and α-glucose
*2 molecules of β-glucose
2 molecules of β-galactose
2 molecules of α-glucose
At the sucrose hydrolysis the following compounds will form:
*α-glucose and β-fructose
β-galactose and α-glucose
2 molecules of β-glucose
D. 2 molecules of β-galactose
E. 2 molecules of α-glucose
720.
In nature, disaccharides may exist both independently and as a part of many glycosides
of plant and bacterial origin. Which of the pointed compounds are nonreducing disaccharides?
A. cellobiose
B. lactose
C. maltose
D. *sucrose
E. starch
721.
Sucrose relates to the nonreducing disaccharides. Sucrose is decomposed into two
monosaccharides after the hydrolysis. Indicate which monosaccharides are a part of sucrose
molecule:
A. *glucose and fructose
B. glucose and glucose
C. glucose and galactose
D. mannose and fructose
E. fructose and fructose
722.
It is known, that soaps are a salts of higher carboxylic acids (HCA). Which soap has a
liquid consistency and is named as “green soap”?
A. calcium
B. sodium
C. *potassium
D. lithium
E. antimony
723.
What reagent will characterize camphor as ketone?
A. HCl
B. Br2
C. NH3
D. CH3COOH
E. *C6H5NHNH2
724.
What reagent can be used to confirm unsaturated character of camphor?
A. oxidation on the air
B. *bromine water
C. HNO3
D. HNO2
E. H2SO4
725.
What reagent can be used to get “liquid soap” by the alkaline hydrolysis of fats
(saponification)?
A. *K2CO3
B. NаOH
C. CаO
D. PbO
E. NaHCO3
726.
Stearic acid belongs to the fats content. Chose formula of this acid:
A. C17H33COOH
B. *C17H35COOH
C. C15H31COOH
D. C17H31COOH
E. C19H33COOH
727.
By the chemical structure fats belong to:
A. salts
B. *esters
C. carboxylic acids
D. alcohols
E. aldehydes
728.
Alkaline hydrolysis of fats has name:
A. *saponification
B.
C.
D.
E.
729.
A.
B.
C.
D.
E.
730.
A.
B.
C.
D.
E.
hydration
hydratation
oxidation
hydrolysis
For the transformation of liquid fats into the solid fats the following reaction is used:
sulfonation
chlorination
bromination
*hydration
oxidation
Prostaglandins in their content have:
10 carbon atoms
30 carbon atoms
25 carbon atoms
*20 carbon atoms
15 carbon atoms