Naaimat’s Source to Gas Chromatography
Gas- liquid chromatography is based upon the partition of the analyte between
a gaseous mobile phase and a liquid phase immobilized on the surface of an inert
solid. The concept of gas-liquid was first enunciated in 1941 by Martin and Synge,
who were also responsible for the development of liquid-liquid partition
chromatography. More than a decade has elapsed before he value of gas-liquid
chromatography was demonstrated experimentally.
In gas chromatography, the sample is vaporized and injected onto the head of
a chromatographic column. Elution is brought about by the flow of an inert gaseous
mobile phase. In contrast to most other types of chromatography, the mobile phase
does not interact with molecules of the analyte; its only function is to transport the
analyte through the column. Two types of gas chromatography are encountered:
Gas-solid chromatography
Gas-liquid chromatography
Gas-liquid chromatography finds widespread use in all fields of science, where
its name despite the fact that this usage neglects gas solid chromatography as a
legitimate kind of chromatography.
Gas- liquid chromatography is based upon a solid stationary phase in which
retention of analytes is the consequence of physical adsorption. Gas solid
chromatography has limited application owing to semi permanent retention of active
or polar molecules and severe tailing of elution peaks.
Reference:
1. http://ull.chemistry.uakron.edu/analytical/GC/
2. Principles of Instrumental Analysis, Sloog, Holler, Nieman, Saunders College
Pub 5th Edition (1998)