Curriculum Vitae
Shoufa Han, Professor
Department of Chemical Biology
College of Chemistry and Chemical Engineering, Xiamen University
Shoufa@xmu.edu.cn
Spouse: Yaqin Zhu
Children: Fangzheng Han, Fangping Han, and Fangzhou Han
Professional Positions

2006-present; Professor, Department of Chemical Biology, Xiamen University, China

2008-2009, Group leader, Molecular Cloning Laboratories, South San Francisco, CA

2003-2006; Postdoctoral fellow/Research associate, Department of Molecular Biology,
The Scripps Research Institute, La Jolla, CA, USA
Education

University of Toledo, OH, Ph.D. (2003) Chemistry

Institute of Chemistry, Chinese Academy of Science, M.S. (1999) Polymer Chemistry

Beijing University, B. S. (1996, Chemistry)
Publications
1.
Multivalent
mannose-displaying
nanoparticles
constructed
from
poly{styrene-co-[(maleic anhydride)-alt-styrene]}.
Organic and Biomolecular Chemistry. 2009, 7(10), 2040-2045
Su R, Li L, Chen X, Han J, Han S*
2.
Poly(styrene-alt-maleic anhydride) derivatives as potent anti-HIV microbicide
candidates
Bioorganic and Medicinal Chemistry Letter, 2009, 19(7):1903-1907
Fang W, Cai Y, Chen X, Su R, Chen T, Xia N, Li L, Yang Q, Han J*, Han S*
1
3.
Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking
Nature Chemical Biology, 1, 93-97, 2005
Shoufa Han, Brian E. Collins, Per Bengtson, and James C. Paulson,
4.
Sialoside analog arrays for rapid identification of high affinity siglec ligands,
Journal of the American Chemical Society, 130 (21), 6680–6681, 2008
Ola Blixt, Shoufa Han, Liang Liao, Ying Zeng, Julia Hoffmann, James C. Paulson;
5.
Bi-functional CD22 ligands use multimeric immunoglobulins as protein scaffolds in
assembly of immune complexes on B cells,
Journal of the American Chemical Society, 2008, 130 (14), pp 4578–4579
Mary O’Reilly, Brian E. Collins, Shoufa Han, Liang Liao, Cory Rillahan, Pavel I. Kitov,
David R. Bundle and James C. Paulson;
6.
On-Virus Construction of Polyvalent Glycan Ligands for Cell-Surface Receptors;
Journal of the American Chemical Society, 2008, 4578 - 4579
Eiton Kaltgrad, Mary O'Reilly, Liang Liao, Shoufa Han, James C. Paulson, M. G. Finn
7.
Synthesis of 9-substituted sialic acids as probes for CD22-ligand interactions on B
cells Frontiers in Modern Carbohydrate Chemistry, 2006, 2-16 Shoufa Han, Brian E.
Collins and James C. Paulson
8.
High-affinity ligand probes of CD22 overcome the threshold set by cis ligands to allow
for binding, endocytosis, and killing of B cells
Journal of Immunology, 2006, 177: 2994-3003
Brian E. Collins, Ola Blixt, Shoufa Han, Bao Duong, Hongyi Li, Jay K. Nathan, Nicolai
Bovin, and James C. Paulson
9.
Probing the role of the hyper-reactive histidine residue of arginase
Archives of Biochemistry and Biophysics, 2005, 444(1), 15-26.
Colleluori, Diana M.; Reczkowski, Robert S.; Emig, Compher, Kevin; Han, S; Viola,
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Ronald E.; Christianson, David W.; Ash, David E.
10.
Splicing unnatural amino acids into proteins: a model study
Protein and Peptide Letters, 2004, 11 (2), 107-114
Shoufa Han and Ronald E. Viola
11.
Inhibitor coordination interaction in the binuclear maganese cluster of arginase,
Biochemistry, 2004, 8987-8999
Evis Cama, Stephanie Pethe, Jean-Lue Boucher, Shoufa Han, David E. Ash, Ronald E.
Viola, Daniel Mansuy, and David W. Christianson
12.
Activation of carbonic anhydrase II by active-site incorporation of histidine anologs,
Archives of Biochemistry and Biophysics, 2004, 42(2), 283-289
Illeana Elder, Shoufa Han, Chingkuan Tu, heather Steele, Philip J. Laipis, Ronald E.
Viola, and David N. Silverman,
13.
A facile synthesis of a difluoromethylene analog of
-aspartyl phosphate for inhibition
of L-aspartate- -semialdehyde dehydrogenase
Synlett, 2003, Vol6, 845-846
Shoufa Han, Roger A. Moore, and Ronald E. Viola
14.
Synthesis and evaluation of alternative substrates for arginase
Bioorganic Chemistry, 2002, vol30, 81-94
Shoufa Han, Roger A. Moore, and Ronald E. Viola
15.
A apectrophotometric assay of arginase
Analytical Biochemistry, 295(1), 117-119, 2001
Shoufa Han and Ronald E. Viola
16.
Nonlinear optical polymer filmes based on sol-gel derived silsesquioxanes with
pendant chromophoric subunits embedded in size-matched pores
3
Journal of Sol-Gel Science and Technology, 18 (2) 137-144, 2000
Shoufa Han, Ze Li, Shengxiang Ji, Daorong Dai, Rongben Zhang, Chuanfeng Zhu,
and Chen Wang
17.
Synthesis of a noval self-assembling NLO polymer film,
Chinese Journal of Polymer Science, 20, 417-422, 1999
Shou-fa Han, Dao-rong Dai, Ze Li, Gang Wu, Rong-ben Zhang
18.
Controlled
Free
radical
Double
Ring
Opening
Polymerization
of
8,9-benzo-2-methylene-1,4,6-trioxaspiro [4,4] nonane,
Materials Letters, 31, 137-139, 1997
Xinru Jia, Minqian Li, Shoufa Han, Ce Wang, and Yen Wei,
Patents

High Affinity Siglec Ligands
James Paulson, Brian Collins, Shoufa Han
US patent, Pending, International Filing Date: 2006-10-11

Enzymatic Sialylation of Intravenous Immunoglobulin G
Shoufa Han, Jiahuai Han
Chinese Patent, pending, Filling data: 2007-6-1

poly{styrene-co-[styrene-alt-(maleic
acid,
sodium
salt)]}
as
potent
anti-HIV
microbicides
Shoufa Han, Jiahuai Han, Chen Xiaoping
(Chinese Patent, Filling data: 2008-6-6)

Poly{styrene-co-[styrene-alt-(D-mannopyranosyl-a-O-ethylamidomaleic acid)]} as dual
contraceptive anti-HIV microbicides
Shoufa Han, Jiahuai Han, Su Rongmin
Chinese Patent, Filling data: 2008-6-6
4