Work Programme extract
Fundamental knowledge and basic tools for functional genomics in all organisms
1.1.2 Structural genomics
The objective is to enable researchers to determine, more effectively and at a higher
rate than is currently feasible, the 3-D structure of proteins and other macromolecules
which is important for elucidating protein function and is essential for drug designs.
Topics for fourth call, deadline 9 November 2005:
LSH-2005-1.1.2-1: Structural genomics interdisciplinary initiative – INTEGRATED
PROJECT. The objective should be the high-throughput determination of the threedimensional structure of macromolecules (proteins, RNA, complexes…) in an
interdisciplinary and international effort, with special emphasis on the development of the
necessary technologies and bioinformatics tools to achieve this, in particular for new folds
or for macromolecules presenting particular difficulties for structural determination. The
project should be organised around a common theme in terms of target selection.