Program Director/Principal Investigator (Last, First, Middle):
Nickells, Robert W.
For New and Renewal Applications (PHS 398) – DO NOT SUBMIT UNLESS REQUESTED
For Non-competing Progress Reports (PHS 2590) – Submit only Active Support for Key Personnel
Nickells, Robert W.
ACTIVE
P30 EY016665-01 (Brandt)
07/01/05-6/30/10
1.2 calendar
NIH/NEI
$388,000
Core Grant for Vision Research
This is a core facilities grant to the Department of Ophthalmology and Visual Sciences at the University of
Wisconsin. The CORE provides 1) Gene Therapy/Quantitative Molecular Biology, 2) Pathology and In vivo
Imaging, and 3) Animal and Eye Organ Culture. Dr. Nickells is the co-Director of the Molecular Biology
CORE.
Rapid Response Initiative Grant (Nickells)
01/01/09-12/31/09
1.2 calendar
University of Wisconsin Eye Research Institute
$30,000
Affect of GFAP on neurite outgrowth in a retinal explant model
This application requests funds to explore the stimulatory and growth permissive functions of microglia on
axonal growth from retinal ganglion cells. It provides supplementary funding for the project described in
pending application R21 EY019554 (below).
R01 EY018869 (Nickells)
02/01/09-01/31/14
2.4 calendar
NIH/NEI
$230,000
Characterization of RGC death susceptibility alleles
This is an application to allow continued study of the Rgcs1 locus in mice with emphasis on its role in
modulating ganglion cell death in glaucoma.
R01 EY12223-09 (Nickells)
07/01/09-06/30/14
6.0
calendar
NIH/NEI
$450,096
The molecular mechanism of retinal ganglion cell death
This is a competitive renewal of EY12223. This grant examines further the role of Bax in ganglion cell
death particularly in evaluating the molecular state of cells arrested at the Bax-stage of apoptosis.
PENDING
Characterization of RGC death susceptibility alleles
Principal Investigator: Robert W. Nickells, PhD
Agency: NEI/NIH
Type: R01EY018869-01S1 Period: 10/01/2009-09/30/2011
This is an ARRA competitive revision grant (NOT-OD-09-058) for the PI’s existing R01. The application
adds 2 more specific aims to this project.
Total Annual Direct Costs: $251,461
Characterization of RGC death susceptibility alleles
Principal Investigator: Robert W. Nickells, PhD
Agency: NEI/NIH
Type: R01EY018869 (primary) and R01EY012223 (secondary)
Period: 09/30/2009-08/31/2010
This is an administrative supplement request (NOT-EY-09-002) for equipment upgrades to support 2
existing R01 grants.
Total Annual Direct Costs: $405,000
PHS 398/2590 (Rev. 11/07)
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Program Director/Principal Investigator (Last, First, Middle):
Nickells, Robert W.
OVERLAP
None of these projects overlap.
Schlamp, Cassandra L.
NONE
Yandell, Brian S.
ACTIVE
5 R01 DK058037-07 (Attie)
NIH/NIDDK
The Genetics of Obesity and Diabetes.
06/01/06 – 5/31/11
$1,326,388
2.4 calendar
5 R01 GM074244-03 (Broman)
06/01/05 - 05/31/10
0.6
calendar
NIH/NIGMS
$176,956
Statistical Methods and Software for QTL Mapping
This project aims to develop improved model selection methods of multiple QTL mapping in experimental
crosses, develop improved methods for the analysis of recombinant inbred lines and related strains, and
develop and disseminate the R/qtl software for QTL mapping.
R01 GM069430-01 (N Yi, Alabama Birmingham)
06/01/05 - 5/31/10
2.4 calendar
NIH/NIGMS
$185,596
Bayesian Methods for Mapping Complex Epistatic Genes.
This project is to develop Bayesian model selection methods and computer software for mapping epistatic
genes in experimental crosses.
R01 EY018869 (Nickells)
02/01/09-01/31/14
2.4 calendar
NIH/NEI
$230,000
Characterization of RGC death susceptibility alleles
This is an application to allow continued study of the Rgcs1 locus in mice with emphasis on its role in
modulating ganglion cell death in glaucoma.
PENDING
R01 (Attie)
11/1/09 -10/31/14
NIH/NIDDK
Gene & gene networks associated with obesity & diabetes. [Impact/Priority 17; 7.0%]
R01 (Yi)
7/1/10-6/30/15
NIH/NIGMS
Bayesian Methods for Genome Wide Interacting QTL mapping.
R01 (Hoeschele)
7/1/10-6/30/12
NIH/NIGMS
Highly multivariate methods for QTL mapping in systems genetics.
(Brunet)
NSF/IOS
1/1/10-12/31/12
1.2 calendar
1.2 calendar
consultant
0.6 calendar
The influence of environmental factors on floral traits and associated changes in gene expression.
(Splitter)
NIH/AI-09-101
PHS 398/2590 (Rev. 11/07)
5/01/10-4/30/15
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0.5 calendar
Program Director/Principal Investigator (Last, First, Middle):
Nickells, Robert W.
Brucella spp. immunomodulatory factors for protection.
(Broman)
NIH/NIGMS
Statistical methods and software for QTL mapping.
OVERLAP
NONE
PHS 398/2590 (Rev. 11/07)
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Continuation Format Page
6/1/10-5/31/15
0.6 calendar