Program Director/Principal Investigator:
(Last, first)
PHS 2590/RPPR OTHER SUPPORT FORMAT PAGE
NEW SENIOR/KEY PERSONNEL (D.2.b)
BENNETT, P.
ACTIVE
Investigator Award (Bennett)
Howard Hughes Medical Institute
09/01/09
$581,317
– 08/31/14 6.00 calendar
Gene Cloning and Targeting for Neurological Disease Genes
This award supports the PI’s program to map and clone the gene(s) implicated in the development of
Alzheimer’s disease and to target expression of the cloned gene(s) to relevant cells.
R01 HG 000000 (Daumier) 03/01/06
– 02/28/15
3.00 calendar
NIH/NHGRI $196,639
Identification of the Risk Factor Genes for Alzheimer’s Disease
The major goals of this project are to identify of new Alzheimer’s disease genes and predicting Alzheimer’s disease.
Industry Sponsored Clinical Trials Aggregated Effort 1.56 calendar
Each of these individual projects has a varying need of effort depending on the type of activity currently in progress: protocol development, start-up, patient recruitment, enrollment, follow-up, monitoring, data analysis, publication, and closeout. Faculty determines each project's need and adjust their effort between projects within the total aggregated effort assigned to the clinical projects. Effort is reviewed and confirmed by the department based on the activity of each project.
Clinton Pharmaceuticals Corporation (Chopin) 10/1/10 –9/30/13
$195,971
Economic Parameters in Early Detection of CHI
The major goals of this project are to use viral strategies to express the normal p53 gene in human
SCLC cell lines and to study the effect on growth and invasiveness of the lines.
Gross Phamaceuticals, Inc.(Poe/Chopin)
Economic Analysis Patients vs. Doctors
02/25/10-08/31/17
$1,110,469
The major goals of this project are to determine how CFRD contributes to lung function decline.
(THIS AWARD)
2 R01 HL 000000-14 (Anderson)
NIH/NHLBI
Chloride and Sodium Transport in Airway Epithelial Cells
OVERLAP No Overlap
RICHARDS, L.
No Other Support
CHANGES IN OTHER SUPPORT (D.2.c)
ANDERSON, R.R.
ACTIVE
(THIS AWARD)
03/01/00
$186,529
– 02/28/15 1.20 calendar
OMB No. 0925-0001 (Rev. 08/12 Approved Through 8/31/2015) Page
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Other Support Format Page

Program Director/Principal Investigator:
(Last, first)
R01 HL 000000 (Anderson)
NIH/NHLBI
Chloride and Sodium Transport in Airway Epithelial Cells
03/01/00 – 02/28/15
$186,529
3.60 calendar
The major goals of this project are to define the biochemistry of chloride and sodium transport in airway epithelial cells and clone the gene(s) involved in transport.
R01 HL 00000 (Baker)
NIH/NHLBI
Ion Transport in Lungs
04/01/10
$122,717
– 03/31/14 1.20 calendar
The major goal of this project is to study chloride and sodium transport in normal and diseased lungs.
R000 (Anderson) 09/01/98 – 08/31/13 1.20 calendar
Cystic Fibrosis Foundation
Gene Transfer of CFTR to the Airway Epithelium
$43,123
The major goals of this project are to identify and isolate airway epithelium progenitor cells and express human
CFTR in airway epithelial cells.
(NEW)
R01 DK000000-01 (Zimmerman)
NIH/NIDDK
9/1/2012 – 8/31/2016
$187,265
1.20 calendar
Cystic Fibrosis Related Diabetes and Lung Function
The major goals of this project are to determine how CFRD contributes to lung function decline.
OVERLAP No Overlap
INACTIVE
DCB 950000 (Anderson)
National Science Foundation
12/01/2008
– 11/30/2011
$82,163
2.40 calendar
Liposome Membrane Composition and Function
The major goals of this project are to define biochemical properties of liposome membrane components and maximize liposome uptake into cells.
HERNANDEZ, M.
ACTIVE
R01 CA 33333 (Hernandez)
NIH/NCI
4/1/2005 – 3/31/2015
$110,532
3.60 calendar
Gene Therapy for Small Cell Lung Carcinoma
The major goals of this project are to use viral strategies to express the normal p53 gene in human SCLC cell lines and to study the effect on growth and invasiveness of the lines.
(NEW)
P01 CA 12222 (Chen)
NIH/NCI
7/1/2011 – 6/30/2016
$104,428 (sub only)
Mutations in p53 in Progression of Small Cell Lung Carcinoma
1.80 calendar
The major goals of this subproject are to define the p53 mutations in SCLC and their contribution to tumor progression and metastasis.
BE 55555 (Hernandez)
American Cancer Society p53 Mutations in Breast Cancer
9/1/1996
$86,732
– 8/31/2013 1.80 calendar
The major goals of this project are to define the spectrum of p53 mutations in human breast cancer samples and correlate the results with clinical outcome.
OMB No. 0925-0001 (Rev. 08/12 Approved Through 8/31/2015) Page
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Other Support Format Page

Program Director/Principal Investigator:
(Last, first)
(THIS AWARD)
R01 HL 44444 (Anderson)
NIH/NHLBI
Chloride and Sodium Transport in Airway Epithelial Cells
3/1/2000
$186,529
– 2/28/2014 0.60 calendar
OVERLAP There was scientific overlap between aim 2 of R01 CA 33333 and aim 4 of project 2 in P01 CA
12222. In conjunction with agency staff, it was decided to remove aim 4 of project 2 from the P01 and adjust the budget and PI level of effort accordingly.
OMB No. 0925-0001 (Rev. 08/12 Approved Through 8/31/2015) Page
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Other Support Format Page