Acute Respiratory Failure and Obstetrics 4/10/10 OH PY Mindmaps - causes: asthma, pulmonary oedema and infection Asthma - can use B2 agonists and corticosteroids without adverse fetal outcome APO - determine cause -> can be from tocolysis with beta-agonists NIV, diuresis, O2 ETT if required can be due to tocolytics ARDS - low TV and permissive hypercapnia -> fetal acidosis which reduces oxygen binding to fetal Hb -> try and keep PaCO2 < 45, PaO2 > 70mmHg (no human trials on this to confirm this management) - few case reports using NO - delivery of fetus doesn’t appear to result in marked improving in respiratory failure Acid Aspiration - high risk: decreased gastric emptying, increased gastric acidity and volume, increased abdominal pressure - bronchoscopy for large pieces - no role for steroids or BAL - only use antibiotics in proven infection Venous Air Embolism - can occur at any time but more common @ C/S - air enters subplacental venous sinuses - sudden SOB, CP, tachycardia, hypoxia -> cardiac arrest - mill wheel murmur, ST depression - FiO2 1.0, left lateral and head down, aspirate CVL if in RV, hyperbaric O2 in those with paradoxical cerebral embolism Respiratory Distress in Labour + Cardinal Signs Peripartum cardiomyopathy: cardiomegaly, S3 Jeremy Fernando (2011) Venous thromboembolism with PE: swollen, painful calf, R heart failure, ECG - S1Q3T3, ST, R strain, CTPA - filling defect AFE: Haemodynamic collapse, DIC, seizure, bleeding Air embolism: hypotension, cardiac mill wheel murmur Pre-eclampsia: HTN, proteinuria Tocolytic pulmonary oedema: Tocolytic administration, rapid improvement Aspiration penumonitis: Hx od vomiting or silent aspiration, CXR findings Pneumomediastinum: occurs during delivery Other causes as in non-pregnant patient Jeremy Fernando (2011)