Table 1. Bland and Altman analysis of the aMT6 profile parameters obtained from the 36 hr and 56 hr urine collections in healthy volunteers
Urinary aMT6s index
Subjects
(n)
Mean of the differences* (
(56 hr -36 hr)

95% CI)
SD
Limits of agreement** (

95% CI)
Achrophase
(hr)
Mesor
(ng/hr)
5
5
0.5
27
(-0.1; 1.1)
(-173; 227)
0.5
161
Lower
-0.4
(-1.5; 0.7)
-289
(-659; 80)
Upper
1.4
(0.3; 2.5)
343
(-26; 712)
Amplitude
(ng/hr)
5
27
(-173; 226)
160
-288
(-656; 79)
341
(-26; 709)
* Mean of the differences: average bias between the estimates obtained from the 36 hr and the 56 hr collections
** Limits of agreement: mean of the differences

1.96 SD

Table 2.
Bland and Altman analysis of the aMT6 profile parameters obtained from the 36 hr and 56 hr urine collections in the patients with cirrhosis
Limits of agreement** (

95% CI)
Urinary aMT6s index
Subjects
(n)
Mean of the differences* (

95% CI)
(56 hr -36 hr)
SD
Lower Upper
Achrophase
(hr)
Mesor
(ng/hr)
Amplitude
(ng/hr)
8
8
8
-0.5
(-1.9; 0.9)
41
(-113; 195)
115
(-178; 407)
1.7
184
350
-3.9
-320
-571
(-6.5; -1.3)
(-595; -45)
(-1093; -48)
* Mean of the differences: average bias between the estimates obtained from the 36 hr and the 56 hr collections
** Limits of agreement: mean of the differences

1.96 SD
2.9
402
800
(0.3; 5.4)
(127; 677)
(277; 1323)

Table 3.
Summary suppression measures in the healthy volunteers and in the patients with cirrhosis, by calculation method
Average
Method 1 Method 2
Summary suppression measures
Weighted average
Method 1 Method 2 Method 1
Sum
Method 2
Healthy volunteers
(n=8)
16

11
Patients with cirrhosis
(n=18)
Values expressed as mean

1SD
5

19
25

17

16
23
117

58

79
118
186

187

103
74
92

32

73
114
141

95

102
139