Genetics 14a - recognize that offspring can resemble parents in inherited traits and learned behaviors (GPS) 14b - discuss what a gene is and the role genes play in the transfer of traits (GPS) 14c - explain the role of chromosomes in development Background Information: Cells make up the tissues in the human body. Inside each cell is a nucleus that controls the cell and contains genetic information on structures called chromosomes. Humans have 46 chromosomes, or 23 pairs, in each of their body cells. The chromosomes are made of thousands of genes (over 60,000). Each parent contributes half of each chromosome pair to their offspring. Genes give humans their physical traits (Phenotype) and come in pairs (Genotype). Half of the pair comes from the mother, while the other half comes from the father. Genes are inherited, and there are different forms called alleles. Some genes are dominant or stronger and will appear more often. Others are recessive or hidden and will appear less often. Dominant genes are always represented by a capital letter. Recessive genes are always represented by a lower-case letter. If an organism has two copies of the same allele, then the organism is homozygous (home-same, zygous-genes) for that trait (AA, aa). If an organism has two different alleles (Bb), then it is heterozygous (hetero-different, zygous-genes). Read The Very Ugly Bug by Liz Pichon. Discuss different traits of the bugs in the story. Create a chart similar to the one below. Bug types: 1. 2. 3. 4. eyes head Ugly bug Green skinny bug Blue striped bug Red polka dot bug The genetics of different bugs in the story: Genotype Phenotype EE or Ee Tiny Eyes ee Big, Googly Eyes HH or Hh Smooth, Steady Head hh Lumpy, Wobbly Head BB or Bb No Hair, Smooth Back bb Hairy Back LL or Ll No Spotted Legs ll Spotted Legs WW or Ww No Wings ww Fluttery Wings body legs Wings Using the table above, identify the traits of The Very Ugly Bug. Dominant Allele Recessive Allele Identify the characters’ traits: Dominant Character Trait Allele Red Bug Tiny eyes Green Bug Smooth back Blue Bug Fluttery wings Recessive Allele Genotype (allele pair) Genotype Phenotype (physical trait) Phenotype Homozygous or Heterozygous? Create your own Very Ugly Bug using the alleles attached. Cut out all 28 chromosomes (2 sets of 14) on the lines and place each pair face down, hiding the letters. These are the chromosomes from the parents. Group same size Chromosomes together – both pink and blue. Select one set of same size alleles together, one blue (father) and one pink (mother), face-down. Turn over the new blue/pink pairs to reveal the genotype and phenotype. These are the alleles for your offspring. There should be 7 sets. Using the table below as a guide, construct a species of a very ugly bug with a Styrofoam ball, colored construction paper, chenille stems, pins, and glue. Your construction paper “baby” bug should accurately portray your description. Genotype EE or Ee ee HH or Hh hh BB or Bb bb SS or Ss ss WW or Ww ww AA or Aa aa LL or Ll ll Phenotype Tiny Eyes Big, Googly Eyes Smooth, Steady Head Lumpy, Wobbly Head No Hair, Smooth Back Hairy Back No Spotted Legs Spotted Legs No Wings Fluttery Wings Long Antennae Short Antennae Long Legs Short Legs Which of your “created” bug’s traits are heterozygous? Which are homozygous? List the pairs of alleles below. Heterozygous Homozygous Describe the genotype and phenotype of your “created” bug. Genotype Phenotype Are there any baby bugs around the classroom that are identical? Pretend all the baby bugs are set free into open land with plenty of food to eat. However, there are predators that can see BIG eyes really well. Explain what you think might happen to the baby bugs with BIG eyes? Questions: What is the Phenotype for Bb when b=hairy back and B=no hair on back? _____________________________________________________________________________________ What is a phenotype? What is a genotype? _____________________________________________________________________________________ _____________________________________________________________________________________ When does a phenotype for a recessive trait appear in an organism? _____________________________________________________________________________________ _____________________________________________________________________________________ W=no wings and w=wings, what is the phenotype for Ww? _____________________________________________________________________________________ W=no wings and w=wings, what is the phenotype for ww? _____________________________________________________________________________________ W=no wings and w=wings, what is the phenotype for WW? _____________________________________________________________________________________ L=long legs and l=short legs, what is the genotype for a bug with short legs? _____________________________________________________________________________________ L=long legs and l=short legs, what is the genotype for a bug with long legs? _____________________________________________________________________________________ A=long antennae and a=short antennae, what is the genotype for a homozygous bug with long antennae? _____________________________________________________________________________________ A=long antennae and a=short antennae, what is the genotype for a homozygous bug with short antennae? _____________________________________________________________________________________ A=long antennae and a=short antennae, what is the genotype for a heterozygous bug with short antennae? _____________________________________________________________________________________ Parent Chromosomes – Allele Pairs Father – Blue Mother - Pink A a B b E e H h L l S s W w