College of Health Sciences, Jeddah
Pharmacy Department
/‫إسم الطالب‬
Pharmaceutical Chemistry
2nd Theoretical quiz
10th January 2007
-------------------------------------------------------------------------------------------------------I.
Mark the following statements true () or false (X) with correction of the
false (Penalty rule will be applied)
(8 points)
1.
As the lipid part of lipoprotein increase the density of the lipoprotein decrease.
2.
As the protein part of lipoprotein increase the density of the lipoprotein decrease.
3.
The protein content in VLDL and chylomicrons is less than that in HDL.
4.
Albumins are very soluble in water, coagulated by heat, and precipitated by
saturated solution of salts.
5.
During protein purification, ammonia is used for refolding of denaturated protein.
6.
While argenine and leucine are essential amino acids, glutamic and lysine are
nonessential.
7.
The specific gravity of fats and lipids are always less than one.
8.
One of the fatty acids present in compound lipid is unsaturated fatty acid.
II.
1.
Complete the following sentences:
(10 points)
Protein denaturation can be achieved by chemical means as ……………… and
………………………..…....
2.
Protein denaturation can result in biological changes as ……………………… and
……………………………… and ………………………………….…………….
3.
Most of fatty acids are water insoluble can be solubilized by …………………
4.
Rancidity means ……………………………………………………………………
…………………………………………………………………………………….
5.
To protect the food from rancidity, the following measures can be done:
a.
…………………………………………..………………………………
b.
…………………………………………………………………………
c.
…………………………………………………………………………
…………………………………………………………………………………………………..
Dr. Mahmoud Sheha
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IV.
Look to the following lipids and fill in the spaces the after-mentioned
statements
(6 points)
O
O
R1
R1
O
.
O
O
O
N
O
P
O
Compound I
R1
P
O
Compound II
O
O
O
R1
NHCOR
HO
HO
O
O
O
O
O
(CH2)12 - CH3
OH
HO
R1
O
N
O
O
O
O
R2
O
OH
OH
OH
O
P
O
OPO3
Compound III
OH
Compound IV
OH
OPO3
1.
Compounds …..……, ……. …, and …….. … are examples of phospholipids.
2.
Compound ………..….. is example of sphingolipids.
3.
Compound …………... contains inositol but compound ……..… contains sugar.
V.
Write shortly about the following:
1.
Conjugated proteins, enumerate at least five groups with examples.
2.
Biological importance of lipid
(6 points)
…………………………………………………………………………………………………..
Dr. Mahmoud Sheha
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