Sodium/Potassium Local ionic currents pump uses ATP to Na+ channels close cause resting pump ions by potential to rise active transport Membrane depolarises to +40mV K+ diffuses out of the axon Na+ diffuses into axon All Na+ are open Sodium ions pumped out of axon K+ channels open Resting potential of -70mV achieved Membrane repolarises Potassium ions pumped into axon Threshold potential achieved Membrane potential falls to -80mV and becomes Hyperpolarised Voltage gated Na+ channels begin to open Action potential propagation Time /ms Sodium ions pumped out of axon Resting potential re-established Potassium ions pumped into axon K+ channels close Sodium/Potassium pump uses ATP to pump ions by active transport Potential Difference /mV