Supplement Table and Figures
Ezra et al. 2015
Microprocessor-Based Integration of Microfluidic Control for the Implementation of Automated
Sensor Monitoring and Multithreaded Optimization Algorithms
Elishai Ezra1, Idan Maor1, Danny Bavli1, Itai Shalom1, Gahl Levy1, Sebastian Prill2, Magnus S Jaeger2, Yaakov Nahmias1,3,*
Grass Center for Bioengineering, The Hebrew University of Jerusalem, Edmond J. Safra Campus, 91904, Jerusalem, Israel
Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (Fraunhofer IZI-BB), 04103, Potsdam, Germany
3 Department of Cell and Developmental Biology, The Hebrew University of Jerusalem, Edmond J. Safra Campus, 91904, Jerusalem, Israel
1
2
* Correspondence should be addressed to:
Prof. Yaakov Nahmias
Email: ynahmias@cs.huji.ac.il
Table S1. List of components
Company
Name
Part
Quantity
Toshiba
8 ch. High voltage source driver
TD62783
6
Microchip
Digital POT
MCP4131
2
Toshiba
Voltage regulator
TA7818F
2
Toshiba
Voltage regulator
TA7824F
1
GHI electronics
FEZ Spider Gadgeteer
SPDR1
1
GHI electronics
Extension board
Hub AP5
1
GHI electronics
USB client Dual Power module
USBDP
1
GHI electronics
3.5" LCD touchscreen display
TE35
1
GHI electronics
USB host module
USBHT
1
GHI electronics
RS-232 module
RS232
1
GHI electronics
Ethernet module
ENC28
1
GHI electronics
Serial camera
L1
1
Resistors 4.8K ohm
2
Resistors 100 ohm
2
Capacitors 10uF
7
Festo
Pressure manifold
MH1
2
Festo
Pressure regulator
VPPE
2
Fluigent
Pressurized reservoirs
Fluiwell-1C
BST
Thick film enzymatic Lactate sensor
PalmSense
Potentiostat
11
1
EmStat3 OEM
1
Supplement Table and Figures
Ezra et al. 2015
Figure S1. Printed circuit board (PCB) 2-layers layout of the high-current electronic interface. Each color (brown/black) indicates different
layer. Green squares indicate placement for the following electrical components: 6 source drivers for the control of the digital interface, two
digital resistors for the control of the analog interface, 3 voltage regulator allowing for a centralized powering of the system, and a series of
capacitors, for the filtration of voltage ripples and spikes.
Supplement Table and Figures
Ezra et al. 2015
Figure S2. Electronic circuit. The circuit specifies the
inner connections of the high-current electronic
interface as they were implemented in the PCB layout.
The upper side of the schematics specify the connectivity
of the digital interface, where each of the six source
drivers receive low current digital control signals
directly from the Gadgeteer, and drive high current
digital signals to the manifolds. On the bottom of the
schematics the analog interface is specify, composed of 4
passive resistors and two digitally controlled resistors.
The digital resistors are controlled with I2C data
protocol, provided by the Gadgeteer. Three-voltage
regulators were utilized for powering the Gadgeteer
mainboard, for supplying the pressure regulator with
power and to set the baseline voltage for the analog
interface circuit.
.