BIOL 318: Immunology, Winter 2013 Instructor: Dr. Kathy Szick-Miranda Office: Science I 316 Phone: 654-6165 Email: kszick-miranda@csub.edu Web: www.csub.edu/~kszick_miranda Office hours: M 10-12; T 3:30-5; W 10-11:30 Lecture and Discussion: T R 10:00-11:40am, Sci II 180 Text Book: Kindt, Goldsby and Osborne. 2007. Kuby Immunology, 6th Edition. W.H. Freeman and Company. Course Description: Study of organs, cells, and molecules responsible for the recognition and disposal of foreign materials that enter the body. Practical considerations and applications. Four hours lecture. Prerequisite: BIOL 201(with a C- or better); BIOL 319 recommended. Course Objectives: Upon completion of this course students will be expected to: •Describe the various cells and organs of the immune system, including the role of each during the immune response. •Compare and contrast innate and acquired immunity, including their specific components and effector mechanisms. •Describe antigens and antibodies and their interactions. •Discuss the immune response to specific pathogens. Academic Policies: It is expected that your work is YOUR work. In the unexpected event of plagiarism and/or dishonesty during exams or for the research term-paper, the student will receive a zero on that activity and be referred to the campus administration for disciplinary action. Please refer to the campus 2009-2011 catalog page 82. Attendance and Participation: I will not record attendance in lecture however, there will often be material presented in lecture that you will not find in your text book. Your overall grade in the course will reflect the extent in which you participate over the course of the quarter. Grading: Grades will be based on the percentage of points accumulated in the course using the scale shown below. A = 94-100 B = 83-86.9 C = 73-76.9 D = 63-66.9 A-= 90-93.9 B- = 80-82.9 C- = 70-72.9 D- = 60-62.9 B+ = 87-89.9 C+ = 77-79.9 D+ = 67-69.9 F = 0-59.9 Assignment Point Values: Exam I Exam II Final Exam (Exam III) Quizzes (top 5 scores) TOTAL 100pts 100pts 100pts 50pts 350pts LECTURE SCHEDULE & READING ASSIGNMENTS Wk Date Topic 1 T-Jan 8 Overview/Intro to course R-Jan 10 Immune system cells and organs Reading CH 1 CH 2 2 T-Jan 15 R-Jan 17 Innate immunity Antigens and antibodies CH 3 CH 4 pp. 76-95 3 T-Jan 22 R-Jan 24 Antigens/antibodies cont. Antigen-antibody interactions CH 4 pp. 95-107 CH 6 4 T-Jan 29 R-Jan 31 EXAM I The complement system CH 7 5 T-Feb 5 R-Feb 7 The major histocompatibility complex The major histocompatibility complex CH 8 CH 8 6 T-Feb 12 R-Feb 14 Cytokines Hypersensitivity CH 12 CH 15 7 T-Feb 19 R-Feb 21 Tolerance and autoimmunity Tolerance and autoimmunity cont. CH 16 CH 16 8 T-Feb 26 R-Feb 28 EXAM II Immune response to infectious diseases CH 18 pp. 447-459 9 T-Mar 5 R-Mar 7 Immune response to infectious diseases Vaccines CH 18 pp. 460-472 CH 19 10 T-Mar 12 R-Mar 14 Immunodeficiencies Experimental systems CH 20 CH 22 F F-Mar22 FINAL 11:00am-1:30pm