BIOL 318: Immunology, Spring 2013
Instructor: Dr. Kathy Szick-Miranda
Office: Science I 316
Phone: 654-6165
Email: kszick-miranda@csub.edu
Web: www.csub.edu/~kszick_miranda
Office hours: M 3:30-5pm, T 3-5pm, Th 8-10am
Lecture: T R 1-2:40pm, BDC 165
Text Book:
Kindt, Goldsby and Osborne. 2007. Kuby Immunology, 6th Edition. W.H. Freeman and Company.
Course Description: Study of organs, cells, and molecules responsible for the recognition and disposal
of foreign materials that enter the body. Practical considerations and applications. Four hours lecture.
Prerequisite: BIOL 201(with a C- or better); BIOL 319 recommended.
Course Objectives: Upon completion of this course students will be expected to:
•Describe the various cells and organs of the immune system, including the role of each during the
immune response.
•Compare and contrast innate and acquired immunity, including their specific components and effector
mechanisms.
•Describe antigens and antibodies and their interactions.
•Discuss the immune response to specific pathogens.
Academic Policies: It is expected that your work is YOUR work. In the unexpected event of plagiarism
and/or dishonesty during exams or for the research term-paper, the student will receive a zero on that
activity and be referred to the campus administration for disciplinary action. Please refer to the campus
2011-2013 catalog page 90.
Attendance and Participation:
I will not record attendance in lecture however, there will often be material presented in lecture that you will
not find in your text book. Your overall grade in the course will reflect the extent in which you participate
over the course of the quarter.
Grading: Grades will be based on the percentage of points accumulated in the course using the scale shown
below.
A = 94-100
B = 83-86.9
C = 73-76.9
D = 63-66.9
A-= 90-93.9
B- = 80-82.9
C- = 70-72.9
D- = 60-62.9
B+ = 87-89.9
C+ = 77-79.9
D+ = 67-69.9
F = 0-59.9
Assignment Point Values:
Exam I
Exam II
Final Exam (Exam III)
Project
TOTAL
100pts
100pts
100pts
50pts
350pts
1
PowerPoint Project
Due Tuesday June 4th
You must choose a specific pathogen from any of the four categories of pathogens we discussed in class
(bacterial, viral, parasitic or fungal, but it MAY NOT be Staphylococcus aureus). Your assignment is to
prepare and submit a PowerPoint presentation with the accompanying notes section completed. The
target audience for your presentation is your classmates (a cohort of students who have just completed
taking an immunology class).
Your presentation/notes must include:
a)
b)
c)
d)
e)
f)
Name and background information for pathogen you chose.
How this pathogen overcomes physical barriers to be able to infect the host.
The host innate immune response to this infection.
The host adaptive immune response to this infection.
How the host complement system fits into the immune response.
One key mechanism or strategy the pathogen utilizes to evade the host immune system and
highlights of other mechanisms/strategies.
g) Reference page (minimum of 5 review or primary research articles)
This assignment requires background research as well as critical thinking about the topics we will have
covered in class. Be sure you include all relevant information (i.e. cells that are involved, cytokines
involved, etc.)
You are encouraged to work in small groups all though individual assignments will also be accepted. If
you do choose to work in a small group, you must also turn in a page signed by each group member
stating that you all contributed equally to the project.
You must submit an electronic version of your presentation and a hard copy with the notes pages
included.
Your presentation should be between 15-20 slides.
2
LECTURE SCHEDULE & READING ASSIGNMENTS
Wk
Date
Topic
1
T-April 2
Overview/Intro to course
R-April 4
Immune system cells
Reading
CH 1
CH 2
2
T-April 9
R-April 11
Immune system organs
FILM
CH 2
3
T-April 16
R-April 18
Innate immunity
Innate immunity
CH 3
CH 3
4
T-April 23
R-April 25
EXAM I
Adaptive immunity
CH 4 pp. 95-107
5
T-April 30
R-May 2
Adaptive immunity
The complement system
CH 4 pp. 76-95
CH 7
6
T-May 7
R-May 9
The major histocompatibility complex
The major histocompatibility complex
CH 8*
CH 8*
7
T-May 14
R-May 16
Cytokines
Review
CH 12
8
T-May 21
R-May 23
EXAM II
Immune response to infectious diseases
CH 18 pp. 447-459
9
T-May 28
R-May 30
Hypersensitivity
Tolerance and autoimmunity
CH 15
CH 16
10
T-June 4
R-June 6
Immunodeficiencies
Vaccines
CH 20
CH 19
F
R-June 13
FINAL 2-4:30pm
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