Title Code Level Credit rating Pre-requisites Type of module Aims Immunology BY235 5 10 CATS BY103 1 semester in extended mode To familiarise the student with the fundamental concepts of immunology and immunity. To form a brief introduction to the range of diagnostic techniques based on immunological reagents. To consider the biology of some immunological diseases Learning outcomes/objectives By the end of the module the students should be able to: 1. appreciate the fundamental characteristics of the immune system, of antigens, and of the immunoglobulin superfamily. 2. understand the genetics of antibody, T-cell receptor and major histocompatability complex diversity. 3. know the type, structure and distribution of the cells, tissues and organs of the immune system. 4. understand the processes involved in, and the control of the humoral and cellular immune responses. 5. know the elements of natural immunity and their role in defence. 6. understand the importance of, and possible mechanisms for, the induction of tolerance. 7. carry out a range of basic immunologically based tests and assays. Content Teaching and learning strategies The module will be delivered by a mixture of lectures, practicals and directed reading. Lectures occupy 30hrs Practicals occupy 9hrs Directed reading 20hrs Private study/assessment 41hrs General characteristics of the immune system Cells and tissues of the immune system Characteristics of antigens Antigen recognition molecules Antibody structure Genetics of antibody and TCR production Clonal selection theory. Major histocompatability complex (MHC) The humoral and cellular responses Induction of tolerance. Natural immunity (incl TLRs) Introduction to practical immunology Some immunological diseases Learning support Current edition of Kuby's Immunology, Goldsby et al. Freeman The Student Central site contains a set of immunology book reviews; links to Immunolgy pages at other universities and a link to a virtual immunoassay site. It also carries practical schedules and results. Assessment tasks 50% Exam and 50% coursework. The exam is 50% MCQ and 50% essay type questions,(L2,3,4,5,) The coursework is a short practical report (L 7)and a short essay (L1, 6). Brief description of module This module will present the student with the principles content and/or aims (maximum 80 underpinning the structure and function of the immune system at words) the molecular, cellular and tissue levels. It will explain how the immune system responds to antigens, and how it avoids responses against self. Area examination board to which module relates Module team/authors/ coordinator Date of first approval Date of last revision Date of approval of this version Version number Field for which module is acceptable and status in that field Course(s) for which module is acceptable and status in course School home External Examiner Biology and Biomedical Sciences Dr. S. L. James 1991 2006 2007 4 Biology- option Biomedical Science- compulsory in approved mode- All other Biology field degrees- optional Pharmacy and Biomolecular Sciences Dr P Nicholls