Sarcoma & Bone Cancer
August 2015
This bulletin covers sarcomas, soft tissue tumours, bone cancers and GISTs and should be of
interest to multidisciplinary teams working in this area.
Sections can include:
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Combined Modality Therapies
Drug Therapy
Pathology, Staging, Polymorphisms & Biomarkers
Prognosis, Survival & Risk Factors
Radiotherapy & Imaging
Supportive Care & Symptom Management
Surgery
Many of the following articles are available online via the NHS Scotland Knowledge Network.
Please use the links where provided and your ATHENS password. A complete list of
available online journals and registration for ATHENS can be found at
www.knowledge.scot.nhs.uk/
If the article you require is not available via the NHS Scotland Knowledge Network and you
would like to request a print copy, please submit your request online at
www.quest.scot.nhs.uk
This bulletin contains a selection of material gathered from a search of the evidence base, and is
not intended to be comprehensive. Professional judgment should be exercised when appraising
the material. The Library takes no responsibility for the wording, content and accuracy of the
information supplied, which has been extracted in good faith from reputable sources. NHSGGC is
not responsible for the content of external internet sites.
Compiled by:
Kirsty Coltart
Subject Librarian
Beatson West of Scotland Cancer Centre
0141 301 7285, kirsty.coltart@ggc.scot.nhs.uk
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General
Cantrell LA, Blank SV and Duska LR. (2015). Uterine carcinosarcoma: A review of the
literature. Gynecologic oncology 137,3:581-588.
Chaudhary P, Bhadana U, Singh RA, et al. (2015). Primary hepatic angiosarcoma. European
Journal of Surgical Oncology 41,9:1137-1143.
Cioffi A and Maki RG. (2015). GI Stromal Tumors: 15 Years of Lessons From a Rare
Cancer. Journal of Clinical Oncology 33,16:1849-1854.
Goldbraich E, Waks Z, Farkash A, et al. (2015). Understanding Deviations from Clinical
Practice Guidelines in Adult Soft Tissue Sarcoma. Studies in Health Technology &
Informatics 216,280-284.
Khan Z, Hussain S and Carter SR. (2015). Tumours of the foot and ankle. Foot 25,3:164-172.
Olivier T, Pop D, Chouiter Djebaili A, et al. (2015). Treating metastatic sarcomas locally: a
paradoxe, a rationale, an evidence? Critical Reviews in Oncology-Hematology 95,1:62-77.
Salemis, N.S. (2015). Skeletal muscle metastasis from breast cancer: management and
literature review. Breast Disease 35,1:37-40.
Van Gompel JJ and Janus JR. (2015). Chordoma and chondrosarcoma. Otolaryngologic
clinics of North America 48,3:501-514.
Combined Modality Therapies
Baldini EH, Wang D, Haas RL, et al. (2015). Treatment Guidelines for Preoperative
Radiation Therapy for Retroperitoneal Sarcoma: Preliminary Consensus of an
International Expert Panel. International journal of radiation oncology, biology, physics
92,3:602-612.
Bedetti B, Wiebe K, Ranft A, et al. (2015). Local Control in Ewing Sarcoma of the Chest
Wall: Results of the EURO-EWING 99 Trial. Annals of Surgical Oncology 22,9:2853-2859.
Haas RL, Gelderblom H, Sleijfer S, et al. (2015). A phase I study on the combination of
neoadjuvant radiotherapy plus pazopanib in patients with locally advanced soft tissue
sarcoma of the extremities. Acta Oncologica 54,8:1195-1201.
O'Kane GM, Cadoo KA, Walsh EM, et al. (2015). Perioperative chemotherapy in the
treatment of osteosarcoma: a 26-year single institution review. Clinical Sarcoma Research
5,17.
Drug & Targeted Therapy
Bellera CA, Penel N, Ouali M, et al. (2015). Guidelines for time-to-event end point
definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the
DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer
trials)+. Annals of Oncology 26,5:865-872.
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Bielack SS, Smeland S, Whelan JS, et al. (2015). Methotrexate, Doxorubicin, and Cisplatin
(MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With
Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative
MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Journal of Clinical Oncology 33,20:2279-2287.
Body JJ, Casimiro S and Costa L. (2015). Targeting bone metastases in prostate cancer:
improving clinical outcome. Nature Reviews Urology 12,6:340-356.
Bui-Nguyen B, Butrynski JE, Penel N, et al. (2015). A phase IIb multicentre study comparing
the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic
untreated soft tissue sarcoma: the TRUSTS trial. European journal of cancer 51,10:13121320.
Davis EJ, Chugh R, Zhao L, et al. (2015). A randomised, open-label, phase II study of
neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients
with localised, high-risk, soft tissue sarcoma. European journal of cancer 51,13:1794-1802.
Hattinger CM, Fanelli M, Tavanti E, et al. (2015). Advances in emerging drugs for
osteosarcoma. Expert Opinion on Emerging Drugs 20,3:495-514.
Jiang Y, Ludwig J and Janku F. (2015). Targeted therapies for advanced Ewing sarcoma
family of tumors. Cancer treatment reviews 41,5:391-400.
Jordan K, Jahn F, Jordan B, et al. (2015). Trabectedin: Supportive care strategies and
safety profile. Critical Reviews in Oncology-Hematology 94,3:279-290.
Lebellec L, Aubert S, Zairi F, et al. (2015). Molecular targeted therapies in advanced or
metastatic chordoma patients: facts and hypotheses. Critical Reviews in OncologyHematology 95,1:125-131.
Poole CD, Connolly MP, Chang J, et al. (2015). Health utility of patients with advanced
gastrointestinal stromal tumors (GIST) after failure of imatinib and sunitinib: findings
from GRID, a randomized, double-blind, placebo-controlled phase III study of regorafenib
versus placebo. Gastric Cancer 18,3:627-634.
Shirley M and Keating GM. (2015). Regorafenib: A Review of Its Use in Patients with
Advanced Gastrointestinal Stromal Tumours. Drugs 75,9:1009-1017.
Silva SC, Wilson C and Woll PJ. (2015). Bone-targeted agents in the treatment of lung
cancer. Therapeutic Advances in Medical Oncology 7,4:219-228.
Toulmonde M, Le Cesne A, Piperno-Neumann S, et al. (2015). Aplidin in patients with
advanced dedifferentiated liposarcomas: a French Sarcoma Group Single-Arm Phase II
study. Annals of Oncology 26,7:1465-1470.
Uehara T, Fujiwara T, Takeda K, et al. (2015). Immunotherapy for Bone and Soft Tissue
Sarcomas. BioMed Research International 2015,820813.
Pathology, Staging, Polymorphisms & Biomarkers
Al-Ibraheemi A, Kozakewich H and Perez-Atayde AR. (2015). Selected Diagnostically
Challenging Pediatric Soft Tissue Tumors. Surgical pathology clinics 8,3:399-418.
Chang L, Shrestha S, LaChaud G, et al. (2015). Review of microRNA in osteosarcoma and
chondrosarcoma. Medical Oncology 32,6:613.
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Cho SJ and Horvai A. (2015). Chondro-Osseous Lesions of Soft Tissue. Surgical pathology
clinics 8,3:419-444.
Hechtman JF, DeMatteo R, Nafa K, et al. (2015). Additional Primary Malignancies in
Patients with Gastrointestinal Stromal Tumor (GIST): A Clinicopathologic Study of 260
Patients with Molecular Analysis and Review of the Literature. Annals of Surgical Oncology
22,8:2633-2639.
James AW and Dry SM. (2015). Diagnostically Challenging Epithelioid Soft Tissue Tumors.
Surgical pathology clinics 8,3:309-329.
Jernigan EW and Esther RJ. (2015). Soft tissue masses for the general orthopedic surgeon.
Orthopedic Clinics of North America 46,3:417-428.
Jo, V.Y. (2015). Myoepithelial Tumors: An Update. Surgical pathology clinics 8,3:445-466.
Ko JS and Billings SD. (2015). Diagnostically Challenging Epithelioid Vascular Tumors.
Surgical pathology clinics 8,3:331-351.
Marano L, Boccardi V, Marrelli D, et al. (2015). Duodenal gastrointestinal stromal tumor:
From clinicopathological features to surgical outcomes. European Journal of Surgical
Oncology 41,7:814-822.
Marino-Enriquez, A. (2015). Advances in the Molecular Analysis of Soft Tissue Tumors and
Clinical Implications. Surgical pathology clinics 8,3:525-537.
Patil DT and Rubin BP. (2015). Genetics of Gastrointestinal Stromal Tumors: A
Heterogeneous Family of Tumors? Surgical pathology clinics 8,3:515-524.
Riddle NN and Gardner JM. (2015). The New Kids on the Block: Recently Characterized
Soft Tissue Tumors. Surgical pathology clinics 8,3:467-491.
Prognosis, Survival & Risk Factors
Joensuu H, Martin-Broto J, Nishida T, et al. (2015). Follow-up strategies for patients with
gastrointestinal stromal tumour treated with or without adjuvant imatinib after surgery.
European journal of cancer 51,12:1611-1617.
Radiotherapy & Imaging
Ahlawat S and Fayad LM. (2015). De Novo Assessment of Pediatric Musculoskeletal Soft
Tissue Tumors: Beyond Anatomic Imaging. Pediatrics 136,1:e194-202.
Becher S and Oskouei S. (2015). PET Imaging in Sarcoma. Orthopedic Clinics of North
America 46,3:409-415.
Byun BH, Kim SH, Lim SM, et al. (2015). Prediction of response to neoadjuvant
chemotherapy in osteosarcoma using dual-phase (18)F-FDG PET/CT. European radiology
25,7:2015-2024.
Cazzato RL, Buy X, Grasso RF, et al. (2015). Interventional Radiologist's perspective on the
management of bone metastatic disease. European Journal of Surgical Oncology 41,8:967974.
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Lazarides AL, Eward WC, Speicher PJ, et al. (2015). The Use of Radiation Therapy in WellDifferentiated Soft Tissue Sarcoma of the Extremities: An NCDB Review. Sarcoma
2015,186581.
Tan TJ, Aljefri AM, Clarkson PW, et al. (2015). Imaging of limb salvage surgery and pelvic
reconstruction following resection of malignant bone tumours. European Journal of
Radiology 84,9:1782-1790.
Wang D, Zhang Q, Eisenberg BL, et al. (2015). Significant Reduction of Late Toxicities in
Patients With Extremity Sarcoma Treated With Image-Guided Radiation Therapy to a
Reduced Target Volume: Results of Radiation Therapy Oncology Group RTOG-0630 Trial.
Journal of Clinical Oncology 33,20:2231-2238.
Zhang Y, Shi H, Li B, et al. (2015). Diagnostic value of 99mTc-MDP SPECT/spiral CT
combined with three-phase bone scintigraphy in assessing suspected bone tumors in
patients with no malignant history. Nuclear medicine communications 36,7:686-694.
Supportive Care & Symptom Management
Coens C, van der Graaf WT, Blay JY, et al. (2015). Health-related quality-of-life results from
PALETTE: A randomized, double-blind, phase 3 trial of pazopanib versus placebo in
patients with soft tissue sarcoma whose disease has progressed during or after prior
chemotherapy-a European Organization for research and treatment of cancer soft tissue
and bone sarcoma group global network study (EORTC 62072). Cancer 121,17:2933-2941.
Stokke J, Sung L, Gupta A, et al. (2015). Systematic review and meta-analysis of objective
and subjective quality of life among pediatric, adolescent, and young adult bone tumor
survivors. Pediatric Blood & Cancer 62,9:1616-1629.
Surgery
Crago AM and Brennan MF. (2015). Principles in Management of Soft Tissue Sarcoma.
Advances in Surgery 49,1:107-122.
Ditzel Filho LF, Prevedello DM, Dolci RL, et al. (2015). The Endoscopic Endonasal Approach
for Removal of Petroclival Chondrosarcomas. Neurosurgery clinics of North America
26,3:453-462.
Ebner F, Friedl TW, Scholz C, et al. (2015). Is open surgery the solution to avoid
morcellation of uterine sarcomas? A systematic literature review on the effect of tumor
morcellation and surgical techniques. Archives of Gynecology & Obstetrics 292,3:499-506.
Kainsbak J, Hansen ES and Dueholm M. (2015). Literature review of outcomes and
prevalence and case report of leiomyosarcomas and non-typical uterine smooth muscle
leiomyoma tumors treated with uterine artery embolization. European Journal of Obstetrics,
Gynecology, & Reproductive Biology 191,130-137.
Kim W, Han I, Kim EJ, et al. (2015). Outcomes of curettage and anhydrous alcohol adjuvant
for low-grade chondrosarcoma of long bone. Surgical oncology 24,2:89-94.
Liu FW, Galvan-Turner VB, Pfaendler KS, et al. (2015). A critical assessment of morcellation
and its impact on gynecologic surgery and the limitations of the existing literature.
American Journal of Obstetrics & Gynecology 212,6:717-724.
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Lopez JF, Hietanen KE, Kaartinen IS, et al. (2015). Primary flap reconstruction of tissue
defects after sarcoma surgery enables curative treatment with acceptable functional
results: a 7-year review. BMC Surgery 15,71.
Rutkowski P, Ferrari S, Grimer RJ, et al. (2015). Surgical Downstaging in an Open-Label
Phase II Trial of Denosumab in Patients with Giant Cell Tumor of Bone. Annals of Surgical
Oncology 22,9:2860-2868.
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Sources used for this bulletin:
OVID MEDLINE, SIGN, NICE and Healthcare Improvement Scotland
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