Sarcoma & Bone Cancer
November 2015
This bulletin covers sarcomas, soft tissue tumours, bone cancers and GISTs and should be of
interest to multidisciplinary teams working in this area.
Sections can include:
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Combined Modality Therapies
Drug Therapy
Pathology, Staging, Polymorphisms & Biomarkers
Prognosis, Survival & Risk Factors
Radiotherapy & Imaging
Supportive Care & Symptom Management
Surgery
Many of the following articles are available online via the NHS Scotland Knowledge Network.
Please use the links where provided and your ATHENS password. A complete list of
available online journals and registration for ATHENS can be found at
www.knowledge.scot.nhs.uk/
If the article you require is not available via the NHS Scotland Knowledge Network and you
would like to request a print copy, please submit your request online at
www.quest.scot.nhs.uk
This bulletin contains a selection of material gathered from a search of the evidence base, and is
not intended to be comprehensive. Professional judgment should be exercised when appraising
the material. The Library takes no responsibility for the wording, content and accuracy of the
information supplied, which has been extracted in good faith from reputable sources. NHSGGC is
not responsible for the content of external internet sites.
Compiled by:
Kirsty Coltart
Subject Librarian
Beatson West of Scotland Cancer Centre
0141 301 7285, kirsty.coltart@ggc.scot.nhs.uk
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General
Choi AH, Hamner JB, Merchant SJ, et al. (2015). Underreporting of Gastrointestinal Stromal
Tumors: Is the True Incidence Being Captured?. Journal of Gastrointestinal Surgery
19,9:1699-1703.
Gaspar N, Hawkins DS, Dirksen U, et al. (2015). Ewing Sarcoma: Current Management and
Future Approaches Through Collaboration. Journal of Clinical Oncology 33,27:3036-3046.
Honore C, Meeus P, Stoeckle E, et al. (2015). Soft tissue sarcoma in France in 2015:
Epidemiology, classification and organization of clinical care. Journal of visceral surgery
152,4:223-230.
Isakoff MS, Bielack SS, Meltzer P, et al. (2015). Osteosarcoma: Current Treatment and a
Collaborative Pathway to Success. Journal of Clinical Oncology 33,27:3029-3035.
Mastoraki A, Toliaki E, Chrisovergi E, et al. (2015). Metastatic Liver Disease Associated with
Gastrointestinal Stromal Tumors: Controversies in Diagnostic and Therapeutic
Approach. Journal of Gastrointestinal Cancer 46,3:237-242.
Smolle MA, Leithner A and Grimer RJ. (2015). Evaluating the British sarcoma referral form.
Annals of the Royal College of Surgeons of England 97,6:434-438.
Valsangkar N, Sehdev A, Misra S, et al. (2015). Current management of gastrointestinal
stromal tumors: Surgery, current biomarkers, mutations, and therapy. Surgery 158,5:11491164.
Combined Modality Therapies
Bishop AJ, Zagars GK, Moon BS, et al. (2015). Combined Limb-Sparing Surgery and
Radiation Therapy to Treat Sarcomas of the Hands and Feet: Long-Term Cancer
Outcomes and Morbidity. International journal of radiation oncology, biology, physics
92,5:1060-1068.
Bishop AJ, Zagars GK, Torres KE, et al. (2015). Combined Modality Management of
Retroperitoneal Sarcomas: A Single-Institution Series of 121 Patients. International journal
of radiation oncology, biology, physics 93,1:158-165.
Fan Z, Patel S, Lewis VO, et al. (2015). Should High-grade Extraosseous Osteosarcoma Be
Treated With Multimodality Therapy Like Other Soft Tissue Sarcomas?. Clinical
Orthopaedics & Related Research 473,11:3604-3611.
Gounder M, Desai V, Kuk D, et al. (2015). Impact of surgery, radiation and systemic therapy
on the outcomes of patients with dendritic cell and histiocytic sarcomas. European journal
of cancer 51,16:2413-2422.
Hompland I and Bruland OS. (2015). Can Imatinib Be Safely Withdrawn in Patients with
Surgically Resected Metastatic GIST? Anticancer Research 35,11:5759-5765.
Joensuu H, Eriksson M, Collan J, et al. (2015). Radiotherapy for GIST progressing during or
after tyrosine kinase inhibitor therapy: A prospective study. Radiotherapy & Oncology
116,2:233-238.
Palassini E, Ferrari S, Verderio P, et al. (2015). Feasibility of Preoperative Chemotherapy
With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and
Superficial Trunk in the Italian Sarcoma Group/Grupo Espanol de Investigacion en
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Sarcomas Randomized Clinical Trial: Three Versus Five Cycles of Full-Dose Epirubicin
Plus Ifosfamide. Journal of Clinical Oncology 33,31:3628-3634.
Tinkle CL, Weinberg V, Braunstein SE, et al. (2015). Intraoperative Radiotherapy in the
Management of Locally Recurrent Extremity Soft Tissue Sarcoma. Sarcoma 2015,913565.
Drug & Targeted Therapy
Bauer S and Joensuu H. (2015). Emerging Agents for the Treatment of Advanced, ImatinibResistant Gastrointestinal Stromal Tumors: Current Status and Future Directions. Drugs
75,12:1323-1334.
Cassier PA, Italiano A, Gomez-Roca CA, et al. (2015). CSF1R inhibition with emactuzumab
in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a
dose-escalation and dose-expansion phase 1 study. Lancet Oncology 16,8:949-956.
Harris SJ, Benson C and Jones RL. (2015). Current and advancing systemic treatment
options for soft tissue sarcomas. Expert opinion on pharmacotherapy 16,13:2023-2037.
Luo Z, Zhang X, Peng W, et al. (2015). A Phase Ii Study of Gemcitabine, Vincristine, and
Cisplatin (Gvp) As Second-Line Treatment for Patients with Advanced Soft Tissue
Sarcoma. Medicine 94,43:e1777.
Mehrotra, B. (2015). Antiresorptive Therapies for the Treatment of Malignant Osteolytic
Bone Disease. Oral & Maxillofacial Surgery Clinics of North America 27,4:561-566.
Mulder RL, Paulides M, Langer T, et al. (2015). Cyclophosphamide versus ifosfamide for
paediatric and young adult bone and soft tissue sarcoma patients. Cochrane Database of
Systematic Reviews 9,006300.
Ray-Coquard IL, Domont J, Tresch-Bruneel E, et al. (2015). Paclitaxel Given Once Per Week
With or Without Bevacizumab in Patients With Advanced Angiosarcoma: A Randomized
Phase II Trial. Journal of Clinical Oncology 33,25:2797-2802.
van den Berg H, Paulussen M, Le Teuff G, et al. (2015). Impact of gender on efficacy and
acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: Secondary
analysis of the Euro-Ewing99-R1 trial. European journal of cancer 51,16:2453-2464.
Pathology, Staging, Polymorphisms & Biomarkers
Doyle, L.A. (2015). Non-mesenchymal Mimics of Sarcoma. Surgical pathology clinics
8,3:493-513.
Doyle, L.A. (2015). Soft tissue tumor pathology: New diagnostic immunohistochemical
markers. Seminars in diagnostic pathology 32,5:370-380.
Kubo T, Shimose S, Fujimori J, et al. (2015). Quantitative (201)thallium scintigraphy for
prediction of histological response to neoadjuvant chemotherapy in osteosarcoma;
systematic review and meta-analysis. Surgical oncology 24,3:194-199.
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Lim J, Poulin NM and Nielsen TO. (2015). New Strategies in Sarcoma: Linking Genomic and
Immunotherapy Approaches to Molecular Subtype. Clinical Cancer Research 21,21:47534759.
Podleska LE, Funk K, Umutlu L, et al. (2015). TNF-alpha and melphalan-based isolated limb
perfusion: no evidence supporting the early destruction of tumour vasculature. British
journal of cancer 113,4:645-652.
Rockberg J, Bach BA, Amelio J, et al. (2015). Incidence Trends in the Diagnosis of Giant
Cell Tumor of Bone in Sweden Since 1958. Journal of Bone & Joint Surgery - American
Volume 97,21:1756-1766.
Shenoy, S. (2015). Small bowel sarcoma: Tumor biology and advances in therapeutics.
Surgical oncology 24,3:136-144.
Prognosis, Survival & Risk Factors
Barrios CH, Blackstein ME, Blay JY, et al. (2015). The GOLD ReGISTry: a Global,
Prospective, Observational Registry Collecting Longitudinal Data on Patients with
Advanced and Localised Gastrointestinal Stromal Tumours. European journal of cancer
51,16:2423-2433.
Bindiganavile S, Han I, Yun JY, et al. (2015). Long-term Outcome of Chondrosarcoma: A
Single Institutional Experience. Cancer Research & Treatment 47,4:897-903.
Chok AY, Goh BK, Koh YX, et al. (2015). Validation of the MSKCC Gastrointestinal Stromal
Tumor Nomogram and Comparison with Other Prognostication Systems: SingleInstitution Experience with 289 Patients. Annals of Surgical Oncology 22,11:3597-3605.
Nataraj V, Batra A, Rastogi S, et al. (2015). Developing a prognostic model for patients with
localized osteosarcoma treated with uniform chemotherapy protocol without high dose
methotrexate: A single-center experience of 237 patients. Journal of surgical oncology
112,6:662-668.
Radiotherapy & Imaging
Baheti AD, Shinagare AB, O'Neill AC, et al. (2015). MDCT and clinicopathological features of
small bowel gastrointestinal stromal tumours in 102 patients: a single institute
experience. British Journal of Radiology 88,1053:20150085.
Bishop AJ, Tao R, Rebueno NC, et al. (2015). Outcomes for Spine Stereotactic Body
Radiation Therapy and an Analysis of Predictors of Local Recurrence. International journal
of radiation oncology, biology, physics 92,5:1016-1026.
Chikarmane SA, Gombos EC, Jagadeesan J, et al. (2015). MRI findings of radiationassociated angiosarcoma of the breast (RAS). Journal of Magnetic Resonance Imaging
42,3:763-770.
Jackson T, Mosci C, von Eyben R, et al. (2015). Combined 18F-NaF and 18F-FDG PET/CT in
the Evaluation of Sarcoma Patients. Clinical nuclear medicine 40,9:720-724.
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Sargar K, Kao SC, Spunt SL, et al. (2015). MRI and CT of Low-Grade Fibromyxoid Sarcoma
in Children: A Report From Children's Oncology Group Study ARST0332. AJR.American
Journal of Roentgenology 205,2:414-420.
Tian F, Hayano K, Kambadakone AR, et al. (2015). Response assessment to neoadjuvant
therapy in soft tissue sarcomas: using CT texture analysis in comparison to tumor size,
density, and perfusion. Abdominal Imaging 40,6:1705-1712.
Supportive Care & Symptom Management
All Wales Medicines Strategy Group Guidance to support the safe use of long-term oral
bisphosphonate therapy. (Sep 2015)
Williams WB and O'Ryan F. (2015). Management of Medication-Related Osteonecrosis of
the Jaw. Oral & Maxillofacial Surgery Clinics of North America 27,4:517-525.
Surgery
Cusido M, Fargas F, Baulies S, et al. (2015). Impact of Surgery on the Evolution of Uterine
Sarcomas. Journal of Minimally Invasive Gynecology 22,6:1068-1074.
Guerin A, Sasane M, Keir CH, et al. (2015). Physician Underestimation of the Risk of
Gastrointestinal Stromal Tumor Recurrence After Resection. JAMA Oncology 1,6:797-805.
Kim IH, Kwak SG and Chae HD. (2015). Prognostic Factors of Patients with Gastric
Gastrointestinal Stromal Tumor after Curative Resection: A Retrospective Analysis of 406
Consecutive Cases in a Multicenter Study. European Surgical Research 55,1-2:12-23.
Park CH, Kim EH, Jung da H, et al. (2015). Impact of periodic endoscopy on incidentally
diagnosed gastric gastrointestinal stromal tumors: findings in surgically resected and
confirmed lesions. Annals of Surgical Oncology 22,9:2933-2939.
Rajani R, Schaefer L, Scarborough MT, et al. (2015). Giant Cell Tumors of the Foot and
Ankle Bones: High Recurrence Rates After Surgical Treatment. Journal of Foot & Ankle
Surgery 54,6:1141-1145.
Rubio-Casadevall J, Martinez-Trufero J, Garcia-Albeniz X, et al. (2015). Role of surgery in
patients with recurrent, metastatic, or unresectable locally advanced gastrointestinal
stromal tumors sensitive to imatinib: a retrospective analysis of the Spanish Group for
Research on Sarcoma (GEIS). Annals of Surgical Oncology 22,9:2948-2957.
Please note that the journal articles you are accessing are subject to the terms and conditions
imposed by the publisher, so there will be a limit on the number of articles an individual may
download or print from a single issue of a journal. You can consult your local NHSGGC library with
any queries.
If you have any questions regarding this or any other library services please contact Library staff –
contact details are at the beginning of the bulletin.
Sources used for this bulletin:
OVID MEDLINE, SIGN, NICE and Healthcare Improvement Scotland
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