Sarcoma & Bone Cancer
February 2015
This bulletin covers sarcomas, soft tissue tumours, bone cancers and GISTs and should be of
interest to multidisciplinary teams working in this area.
Sections can include:
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Combined Modality Therapies
Drug Therapy
Pathology, Staging, Polymorphisms & Biomarkers
Prognosis, Survival & Risk Factors
Radiotherapy & Imaging
Supportive Care & Symptom Management
Surgery
Many of the following articles are available online via the NHS Scotland Knowledge Network.
Please use the links where provided and your ATHENS password. A complete list of
available online journals and registration for ATHENS can be found at
www.knowledge.scot.nhs.uk/
If the article you require is not available via the NHS Scotland Knowledge Network and you
would like to request a print copy, please submit your request online at
www.quest.scot.nhs.uk
This bulletin contains a selection of material gathered from a search of the evidence base, and is
not intended to be comprehensive. Professional judgment should be exercised when appraising
the material. The Library takes no responsibility for the wording, content and accuracy of the
information supplied, which has been extracted in good faith from reputable sources. NHSGGC is
not responsible for the content of external internet sites.
Compiled by:
Kirsty Coltart
Subject Librarian
Beatson West of Scotland Cancer Centre
0141 301 7285, kirsty.coltart@ggc.scot.nhs.uk
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General
Argon A, Doganavsargil B, Unal Yildirim F, et al. (2015). Osteosarcomas of jaw: Experience
of a single centre. Journal of Plastic Surgery and Hand Surgery 49,1:13-18.
Burt A, Berriochoa J, Korpak A, et al. (2015). Treatment of Chest Wall Sarcomas: A Singleinstitution Experience Over 20 Years. American Journal of Clinical Oncology 38,1:80-86.
Daw NC, Chou AJ, Jaffe N, et al. (2015). Recurrent osteosarcoma with a single pulmonary
metastasis: a multi-institutional review. British journal of cancer 112,2:278-282.
Goldberg C, Hoang D, McRae M, et al. (2015). A strategy for the successful management of
dermatofibrosarcoma protuberans. Annals of Plastic Surgery 74,1:80-84.
HaDuong JH, Martin AA, Skapek SX, et al. (2015). Sarcomas. Pediatric clinics of North
America 62,1:179-200.
Lerman DM and Randall RL. (2015). Local control of metastatic sarcoma. Current opinion in
pediatrics 27,1:3-8.
NICE. QS78: Sarcoma: Quality Standards. January 2015
Salemis, N.S. (2015). Skeletal muscle metastasis from breast cancer: management and
literature review. Breast Disease 35,1:37-40.
Szablewski V, Neuville A, Terrier P, et al. (2015). Adult sinonasal soft tissue sarcoma:
Analysis of 48 cases from the French Sarcoma Group database. Laryngoscope 125,3:615623.
Trans-Atlantic RPS Working, G. (2015). Management of primary retroperitoneal sarcoma
(RPS) in the adult: a consensus approach from the Trans-Atlantic RPS Working Group.
Annals of Surgical Oncology 22,1:256-263.
Wong HH, Gounaris I, McCormack A, et al. (2015). Presentation and management of
pulmonary artery sarcoma. Clinical Sarcoma Research 5,1:3.
Combined Modality Therapies
Fujisawa Y, Yoshino K, Kadono T, et al. (2014). Chemoradiotherapy with taxane is superior
to conventional surgery and radiotherapy in the management of cutaneous
angiosarcoma: a multicentre, retrospective study. British Journal of Dermatology
171,6:1493-1500.
Otsuki A, Watanabe Y, Nomura H, et al. (2015). Paclitaxel and carboplatin in patients with
completely or optimally resected carcinosarcoma of the uterus: a phase II trial by the
Japanese Uterine Sarcoma Group and the Tohoku Gynecologic Cancer Unit. International
Journal of Gynecological Cancer 25,1:92-97.
Su W, Lai Z, Wu F, et al. (2015). Clinical efficacy of preoperative chemotherapy with or
without ifosfamide in patients with osteosarcoma of the extremity: meta-analysis of
randomized controlled trials. Medical Oncology 32,2:481.
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Drug & Targeted Therapy
Andreou D, Werner M, Pink D, et al. (2015). Prognostic relevance of the mitotic count and
the amount of viable tumour after neoadjuvant chemotherapy for primary, localised, highgrade soft tissue sarcoma. British journal of cancer 112,3:455-460.
Guan Z, Yu X, Wang H, et al. (2015). Advances in the targeted therapy of liposarcoma.
OncoTargets and therapy 8,125-136.
Dantonello TM, Stark M, Timmermann B, et al. (2015). Tumour volume reduction after
neoadjuvant chemotherapy impacts outcome in localised embryonal
rhabdomyosarcoma. Pediatric Blood & Cancer 62,1:16-23.
De Sanctis R, Bertuzzi A, Basso U, et al. (2015). Non-pegylated liposomal doxorubicin plus
ifosfamide in metastatic soft tissue sarcoma: results from a phase-II trial. Anticancer
Research 35,1:543-547.
Gadducci A and Guerrieri ME. (2015). Pharmacological treatment for uterine
leiomyosarcomas. Expert opinion on pharmacotherapy 16,3:335-346.
Kim SH, Shin KH, Seok SO, et al. (2015). Secondary malignant neoplasms after
osteosarcoma: early onset and cumulative alkylating agent dose dependency. Annals of
Surgical Oncology 22,3:859-865.
Liu Y, Xu Y, Lin N, et al. (2015). High-Dose Methotrexate (HD-MTX) Used as an Adjunct with
Other Chemotherapeutics for the Treatment of Osteosarcoma. Cell Biochemistry &
Biophysics 71,2:1097-1104.
Michelagnoli M, Whelan J, Forsyth S, et al. (2015). A phase II study to determine the efficacy
and safety of oral treosulfan in patients with advanced pre-treated Ewing sarcoma
ISRCTN11631773. Pediatric Blood & Cancer 62,1:158-159.
Schack LH, Mouritsen LS, Elowsson C, et al. (2015). The Danish experience with trabectedin
treatment for metastatic sarcoma: Importance of hyponatremia. Acta Oncologica 54,1:3440.
Trent JC and Subramanian MP. (2014). Managing GIST in the imatinib era: optimization of
adjuvant therapy. Expert Review of Anticancer Therapy 14,12:1445-1459.
Whelan JS, Bielack SS, Marina N, et al. (2015). EURAMOS-1, an international randomised
study for osteosarcoma: results from pre-randomisation treatment+. Annals of Oncology
26,2:407-414.
Pathology, Staging, Polymorphisms & Biomarkers
Gronchi A, Collini P, Miceli R, et al. (2015). Myogenic differentiation and histologic grading
are major prognostic determinants in retroperitoneal liposarcoma. American Journal of
Surgical Pathology 39,3:383-393.
Hourani R, Taslakian B, Shabb NS, et al. (2015). Fibroblastic and myofibroblastic tumors of
the head and neck: comprehensive imaging-based review with pathologic correlation.
European Journal of Radiology 84,2:250-260.
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Huang Q and Ouyang X. (2015). The role of miRNAs in bone metastasis and their
significance in the detection of bone metastasis: a review of the published data. Future
Oncology 11,1:141-151.
Karanian M, Perot G, Coindre JM, et al. (2015). Fluorescence in situ hybridization analysis
is a helpful test for the diagnosis of dermatofibrosarcoma protuberans. Modern Pathology
28,2:230-237.
Kopp LM, Hu C, Rozo B, et al. (2015). Utility of bone marrow aspiration and biopsy in initial
staging of Ewing sarcoma. Pediatric Blood & Cancer 62,1:12-15.
Kubo T, Shimose S, Fujimori J, et al. (2015). Does expression of glucose transporter
protein-1 relate to prognosis and angiogenesis in osteosarcoma?. Clinical Orthopaedics &
Related Research 473,1:305-310.
Sekine M, Imaoka H, Mizuno N, et al. (2015). Clinical course of gastrointestinal stromal
tumor diagnosed by endoscopic ultrasound-guided fine-needle aspiration. Digestive
Endoscopy 27,1:44-52.
Traina F, Errani C, Toscano A, et al. (2015). Current Concepts in the Biopsy of
Musculoskeletal Tumors: AAOS Exhibit Selection. Journal of Bone & Joint Surgery American Volume 97,2:e7.
Prognosis, Survival & Risk Factors
Ben Arush M, Minard-Colin V, Mosseri V, et al. (2015). Does aggressive local treatment have
an impact on survival in children with metastatic rhabdomyosarcoma?. European journal
of cancer 51,2:193-201.
Biswas B, Thakar A, Mohanti BK, et al. (2015). Prognostic factors in head and neck Ewing
sarcoma family of tumors. Laryngoscope 125,3:E112-7.
Federico SM, Gilpin D, Samant S, et al. (2015). Clinical features and outcomes of young
patients with head and neck non-rhabdomyosarcoma soft tissue sarcomas. Head & neck
37,1:76-83.
Frezza AM, Cesari M, Baumhoer D, et al. (2015). Mesenchymal chondrosarcoma:
Prognostic factors and outcome in 113 patients. A European Musculoskeletal Oncology
Society study. European journal of cancer 51,3:374-381.
Groves ML, Zadnik PL, Kaloostian P, et al. (2015). Epidemiologic, functional, and oncologic
outcome analysis of spinal sarcomas treated surgically at a single institution over 10
years. Spine Journal: Official Journal of the North American Spine Society 15,1:110-114.
Lim SM, Yoo CJ, Han JW, et al. (2015). Incidence and Survival of Pediatric Soft Tissue
Sarcomas: Comparison between Adults and Children. Cancer Research & Treatment
47,1:9-17.
Ozer-Stillman I, Strand L, Chang J, et al. (2015). Meta-analysis for the Association between
Overall Survival and Progression-Free Survival in Gastrointestinal Stromal Tumor. Clinical
Cancer Research 21,2:295-302.
Vaynrub M, Taheri N, Ahlmann ER, et al. (2015). Prognostic value of necrosis after
neoadjuvant therapy for soft tissue sarcoma. Journal of surgical oncology 111,2:152-157.
Xie B, Zhang T and Dai C. (2015). Survival outcomes of patients with temporal bone
squamous cell carcinoma with different invasion patterns. Head & neck 37,2:188-196.
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Radiotherapy & Imaging
Brown LC, Lester RA, Grams MP, et al. (2014). Stereotactic body radiotherapy for
metastatic and recurrent ewing sarcoma and osteosarcoma. Sarcoma 2014,418270.
Casey DL, Meyers PA, Alektiar KM, et al. (2014). Ewing sarcoma in adults treated with
modern radiotherapy techniques. Radiotherapy & Oncology 113,2:248-253.
Casey DL, Wexler LH, Fox JJ, et al. (2014). Predicting outcome in patients with
rhabdomyosarcoma: role of [(18)f]fluorodeoxyglucose positron emission tomography.
International journal of radiation oncology, biology, physics 90,5:1136-1142.
Casey DL, Wexler LH, Meyers PA, et al. (2015). Radiation for bone metastases in Ewing
sarcoma and rhabdomyosarcoma. Pediatric Blood & Cancer 62,3:445-449.
Chen YT, Sun HL, Luo JH, et al. (2014). Interventional digital subtraction angiography for
small bowel gastrointestinal stromal tumors with bleeding. World Journal of
Gastroenterology 20,47:17955-17961.
Kambadakone A, Yoon SS, Kim TM, et al. (2015). CT perfusion as an imaging biomarker in
monitoring response to neoadjuvant bevacizumab and radiation in soft-tissue sarcomas:
comparison with tumor morphology, circulating and tumor biomarkers, and gene
expression. AJR.American Journal of Roentgenology 204,1:W11-8.
Kim EY, Chapman TR, Ryu S, et al. (2015). ACR Appropriateness Criteria() Non-Spine Bone
Metastases. Journal of palliative medicine 18,1:11-17.
Miller BJ, Avedian RS, Rajani R, et al. (2015). What is the use of imaging before referral to
an orthopaedic oncologist? A prospective, multicenter investigation. Clinical Orthopaedics
& Related Research 473,3:868-874.
Pressney I and Saifuddin A. (2015). Percutaneous image-guided needle biopsy of clavicle
lesions: a retrospective study of diagnostic yield with description of safe biopsy routes
in 55 cases. Skeletal radiology 44,4:497-503.
Rathmann N, Diehl SJ, Dinter D, et al. (2015). Radioembolization in patients with
progressive gastrointestinal stromal tumor liver metastases undergoing treatment with
tyrosine kinase inhibitors. Journal of Vascular & Interventional Radiology 26,2:231-238.
Shinagare AB, Ip IK, Lacson R, et al. (2015). Gastrointestinal Stromal Tumor: Optimizing the
Use of Cross-sectional Chest Imaging during Follow-up. Radiology 274,2:395-404.
Thiagarajan A and Iyer NG. (2014). Radiation-induced sarcomas of the head and neck.
World Journal of Clinical Oncology 5,5:973-981.
Supportive Care & Symptom Management
Gundle KR, Cizik AM, Jones RL, et al. (2015). Quality of life measures in soft tissue
sarcoma. Expert Review of Anticancer Therapy 15,1:95-100.
Hobusch GM, Lang N, Schuh R, et al. (2015). Do Patients With Ewing's Sarcoma Continue
With Sports Activities After Limb Salvage Surgery of the Lower Extremity?. Clinical
Orthopaedics & Related Research 473,3:839-846.
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Lang NW, Hobusch GM, Funovics PT, et al. (2015). What sports activity levels are achieved
in patients with modular tumor endoprostheses of osteosarcoma about the knee?.
Clinical Orthopaedics & Related Research 473,3:847-854.
Surgery
Aponte-Tinao L, Ritacco LE, Ayerza MA, et al. (2015). Does intraoperative navigation
assistance improve bone tumor resection and allograft reconstruction results?. Clinical
Orthopaedics & Related Research 473,3:796-804.
Aponte-Tinao LA, Ayerza MA, Muscolo DL, et al. (2015). Should Fractures in Massive
Intercalary Bone Allografts of the Lower Limb Be Treated With ORIF or With a New
Allograft?. Clinical Orthopaedics & Related Research 473,3:805-811.
Bernthal NM, Greenberg M, Heberer K, et al. (2015). What are the functional outcomes of
endoprosthestic reconstructions after tumor resection?. Clinical Orthopaedics & Related
Research 473,3:812-819.
Chen K, Zhou YC, Mou YP, et al. (2015). Systematic review and meta-analysis of safety and
efficacy of laparoscopic resection for gastrointestinal stromal tumors of the stomach.
Surgical endoscopy 29,2:355-367.
Capanna R, Scoccianti G, Frenos F, et al. (2015). What was the survival of megaprostheses
in lower limb reconstructions after tumor resections?. Clinical Orthopaedics & Related
Research 473,3:820-830.
Kim IH, Kim IH, Kwak SG, et al. (2014). Gastrointestinal stromal tumors (GISTs) of the
stomach: a multicenter, retrospective study of curatively resected gastric GISTs. Annals
of surgical treatment and research 87,6:298-303.
Liao CH, Yeh CN, Wang SY, et al. (2015). Surgical option for intestinal gastrointestinal
stromal tumors - perioperative and oncological outcomes of laparoscopic surgery.
Anticancer Research 35,2:1033-1040.
Lin AY, Kotova S, Yanagawa J, et al. (2015). Risk stratification of patients undergoing
pulmonary metastasectomy for soft tissue and bone sarcomas. Journal of Thoracic &
Cardiovascular Surgery 149,1:85-92.
Luzzati AD, Shah S, Gagliano F, et al. (2015). Multilevel en bloc spondylectomy for tumors
of the thoracic and lumbar spine is challenging but rewarding. Clinical Orthopaedics &
Related Research 473,3:858-867.
Mastoraki A, Leotsakos G, Mastoraki S, et al. (2015). Challenging diagnostic and therapeutic
modalities for leiomyosarcoma of inferior vena cava. International Journal Of Surgery 13,9295.
Pala E, Trovarelli G, Calabro T, et al. (2015). Survival of modern knee tumor
megaprostheses: failures, functional results, and a comparative statistical analysis.
Clinical Orthopaedics & Related Research 473,3:891-899.
Schuh R, Kaider A, Windhager R, et al. (2015). Does competing risk analysis give useful
information about endoprosthetic survival in extremity osteosarcoma?. Clinical
Orthopaedics & Related Research 473,3:900-906.
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Shen C, Chen H, Yin Y, et al. (2015). Endoscopic versus open resection for small gastric
gastrointestinal stromal tumors: safety and outcomes. Medicine 94,1:e376.
Sourrouille I, Vilcot L, Honore C, et al. (2015). Algorithm for the surgical management of
mesenchymal tumors of the perineum in adults. Diseases of the Colon & Rectum 58,3:304313.
Slade AD, Warneke CL, Hughes DP, et al. (2015). Effect of concurrent metastatic disease
on survival in children and adolescents undergoing lung resection for metastatic
osteosarcoma. Journal of pediatric surgery 50,1:157-160.
Sun L, Li Y, Zhang J, et al. (2015). Prognostic value of pathologic fracture in patients with
high grade localized osteosarcoma: a systemic review and meta-analysis of cohort
studies. Journal of Orthopaedic Research 33,1:131-139.
Wafa H, Reddy K, Grimer R, et al. (2015). Does total humeral endoprosthetic replacement
provide reliable reconstruction with preservation of a useful extremity?. Clinical
Orthopaedics & Related Research 473,3:917-925.
Yang JY, Kong SH, Ahn HS, et al. (2015). Prognostic factors for reoperation of recurrent
retroperitoneal sarcoma: The role of clinicopathological factors other than histologic
grade. Journal of surgical oncology 111,2:165-172.
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Sources used for this bulletin:
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