KAOSI’S SARCOMA
1872
• CHRONIC OR EUROPEAN-
90% OCCRANCE IN OLD MEN OF EASTERN EUROPEN AS MULTIPLE
PURPLE COLOURED SKIN PLAQUES OR NODULES ASYMPTOMATIC
ON LIMBS LOCALISED TO SKIN AND VISCERAS INVOLED IN 10%
OF CASES WITH LAPSES AND REMISSIONS
• LYMPHADENOPATHIC OR
AFRICAN/ENDAMIC –AMONG YOUNG BANTU CHILDERN
•
OF SOUTH AFRICA, WITH LOCALISED OR GENERALISED LYMPH
ADENOPATHY, EXTREMELY AGGRESSIVE , HIGH PREVELANCE
WITH HIV- ASSOCIATED DISEASE
TRANSPLANT ASSOCIATED –AGGRASIVE INVOLVING
LYMPH NODES MUCOSA & VISCERL ORGEN, REGRESS WHEN
IMMUNOSUPRESSIVE THERAPY IS REDUCED
• AIDS ASSOCIATED- IN MALE HOMOSEXUALS,
DIAGNOSIS MAY PRECED THE CLINICAL RECOGNITION OF AIDS,
NO SITE OF PREDILECTION LYMPH NODES , GIT & DIASEMINATED
FORM
KAPOSI’S SARCOMA
KAPOSI’S SARCOMA
KAPOSI’S SARCOMA
KAPOS’S SARCOMA
KAPOSI’S SARCOMA
ORAL MUCOSA
KAPOSI’S SARCOMA
KAPOSI’S SACOMA
HISTOPATHOLOGY X45
TREATMANT
-IONIZING RADIATIONS
COBALT THERAPY,
ELECTRON BEAM THERAPY
-POLY CHEMOTHERAPY-DOXORUBICIN,
-VINCA ALKALOIDS
-BLEOMYCINE
-INTERFON-ALFA,
-HAART