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Welcome to Bio181L!
Section 25, Room 420
What 181L is
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Thinking, Understanding, Investigating, Evaluating
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Not arrive, assembly line, leave
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RIGHT NOW: Read pp. ix & xi in lab manual
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Not sync’ed with most lecture sections, but internally coherent &
mutually reinforcing
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80% of success is just showing up*
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Absences must be excused by Asya Roberts in BSE109 prior to
making up. Contact her as soon as possible. Really.
Her email: asya@email.arizona.edu
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Late is absent. Leaving early is absent.
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Labs cannot be offered week after they are delivered; Avoid
missing a lab
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Missing 2 labs => you’ll be dropped from the course--excused
or otherwise (b/c you’ll have little shot at learning what you
need)
*--Woody Allen
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Absences and Late Work
READ THE SYLLABUS TONIGHT IF YOU HAVEN’T
ALREADY!!!
•http://blc.arizona.edu/courses/181Lab/ => Syllabus
If you only read one part of it make it this:
•http://blc.arizona.edu/courses/181Lab/ => Syllabus => Absences
and late work
Policies & Grading
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Syllabus (Linked on course homepage)
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Assignments
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On-line assessments/tutorials (10%)
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In-class quizzes (15%)
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Lab assignments (LABAs--Lab Activity Based Assignments) (50%)
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Lab Projects & reports (combine to 25%)
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Every assignment is posted & reported on basis of 100%
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For electronic assignments, log in again to see your recorded score
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Also reported to you at the end
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Plagiarism and Cheating
Plagiarism:
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This is a heinous crime
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Read page xiii in the Lab Manual
http://deanofstudents.arizona.edu/studentcodeofconduct
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If you’re in doubt, ask me BEFORE you turn something in
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I will drop you from the class and recommend your expulsion
from the university if you plagiarize
Cheating:
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Keep your eyes on your quizzes
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Its not worth it
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Success in my Class
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Ask questions often
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Read the Lab before class (Highlight important info)
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Be prepared, on time, and behave yourself
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No texting or calling in my class (take it outside, or else I’ll give
you a 0% on the daily quiz)
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Clean up your work station after each lab (untidy work stations
will result in 10% deduction on daily quiz)
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Ask me for help whenever you can
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About me...
My name is Jameson Cumsky, but you
can call me “Jamie”
I’m an undergraduate, a “super-senior”,
majoring in psychology and minoring in
biochemistry and MCB. I’m planning on
going to medical school to become a
psychiatrist. My favorite music is stuff
from the 90’s 
Email: jcumsky@email.arizona.edu
Office Hours: Koffler 209, Fridays 35PM
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My Webpage
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Get there via homepage* => Instructors => 25
*http://blc.arizona.edu/courses/181Lab
(Lab Man yellow page)
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Web page operation
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About you
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Introductions!
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Name?
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Year in school?
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Major/minor?
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Career/personal goals?
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Favorite type of music/artist/video game/tv show?
Meet your neighbors! They’re your group today!
181 Lab ACCOUNTS
GET TO THE COMPUTER!
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Course home page:
http://blc.arizona.edu/courses/181lab (Safari home page)
Click ‘Create Accounts’
NOTE: Do NOT use UANetID psassword!
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Your section number is:
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Bio181L_Go is the way to do your work. Browser bad
(I’ll show you how to download that at the end of class!)
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Time for Introductions
Share your cards with the class (and I)!
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How?
Why?
the Tao of Molecules
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How molecules feel & the world they live in
Primary goals
• Create understanding by observation, reasoning
• Chemical foundations for the course:
• Water & its properties
• non-watery things
• Know molecules as real & tangible things
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When a journalist asked the great physicist Richard
Feynman what single sentence would best
encapsulate all science so far if it were to be the
sole surviving scrap of all we knew, he replied,
“The world is made of atoms.”
From The Secret of Scent, Luca Turin p.28
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Atoms: They’re how life works
The 4 types of biological molecules:
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Nucleic Acids (DNA, RNA): C, H, N, O, P, [Mg++]
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Carbs: C, H, O
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Proteins: C, H, N, O, (S), (P), [traces]
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Lipids (Membranes, Hormones): C, H, N, O, P, (S)
“S.P.O.N.C.H.”
What cannot be done with assemblages of these atoms*
cannot be done by living organisms, nor their cells, nor their
spit, etc.
*OK, fine, there’s the occasional role for Ca++, etc.
Who am I?
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At birth, # protons = # electrons
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Atoms seek completion, which means outermost electron set = 8
(hydrogen, helium it’s just 2)
Freeman Fig. 2.1a
Coloring your world
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Electronegativity
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Jargon
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Covalent bond: The sharing of electrons between atoms, forming
a molecule.
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Polarity: Having an unequally distributed charge. A quality of
molecules. Molecules are polar if they have unevenly distributed
charge, non-polar if they have evenly distributed charge.
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Polar interactions/Hydrogen interactions: The attraction of
molecules to each other on the basis of unevenly distributed
charge
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Non-polar interaction/Hydrophobic interaction: The interaction
between non-polar molecules as a result of there exclusion from
polar interactions.
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Views of Water
(There will be a test)
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H2O
+
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H
See lab manual, p. 0-3
O
H
How to draw molecules
Carbon Hydrogen Oxygen Nitrogen
Figure is from Lab Manual p. 0-5
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Interacting with H2O
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To your StructViewers!
Desktop => Bio181L_Go
NOTE: You’ll need to download this on your personal computer
in order to do the homework!
Homepage => Course Software => Bio181L_Go
Doing it
Computers, stations
Tao_MCB181L (on desktop)
Your assigned names:
Charizard
Zapdos
Venusaur
Moltres
Blastoise
Magikarp
Articuno
Write your group names down!!!
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Evaporation
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First things first--what is it? What’s going on in terms of molecules
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Experiment: Ethanol and water on your arm: which is cooler & why?
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Prediction: based on molecular weight, which should evaporate
more quickly--H2O (2 x 1 + 1 x 16) or CH3CH2OH (5 x 1; 2 x 12; 1 x 16)
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If not, why not?
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Salt--ever tasted your sweat? Or anybody else’s for that matter?
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What benefit might there be to adding NaCl to water that you
are intending to evaporate?
Clean up!
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Oil waste in the hood
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ethanol waste in the sink
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anything too messy wadded up and
discarded
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Wipe down lab areas and leave them in
the same (or better) condition you found
them in!
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TA-lead discussions
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Structures of oil and water
Streaming oil and water
Dissolving salt – or not
Floating a staple
Why does pepper “flee” the scene of a detergent?
Two kinds of drops versus two kinds of surfaces
Alcohols, water, and salt: blending and separating
Density versus hydrophobicity
Sweatin’ to the oldies – NEXT SLIDE YO
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What’s an Assessor?
=>Chatting<=
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What’s vocabulary homework?
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EITHER both versions of the crossword exercise
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OR VocabuWary with a better than threshold score
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For “Atoms & Molecules”, F12, that’s 60,000
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Errors count off. Slowness counts off.
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Homework
due 10 p.m. before lab
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Read Syllabus: http://blc.arizona.edu/courses/181Lab/ => Syllabus
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Download Bio181L_Go on personal computer: This is the
program you will use to do homework!
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Assessor: 181 Intro ’12
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Vocab: Atoms/Mols: CrossWord (both versions) or VocabuWary
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Assessor: Molecular World Tutorial
Next week’s quiz will include
Concepts from today
Atom colors
Deducing partial charges
Lab Manual Ch. 2