Organic Chem~ Macromolecules

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Biochemistry
Macromolecules
(large molecules):
Carbohydrates
Lipids
Proteins
Nucleic Acids
These are Polymers (many parts)
constructed of Monomers (single part)
polymer
polymer
monomer
How to Connect Monomers-
Hydrolysis Breaking apart polymer
Adding water molecule
Connecting MonomersDehydration reaction
Hydrolysis Breaking apart polymer
Adding water molecule
Connecting MonomersDehydration reaction
joining monomers
loss of water molecule
Hydrolysis Breaking apart polymer
Adding water molecule
Connecting MonomersDehydration reaction
joining monomers
loss of water molecule
Hydrolysis Breaking apart polymer
Adding water molecule
Connecting MonomersDehydration reaction
this takes energy
Hydrolysis Breaking apart polymer
Adding water molecule
Connecting MonomersDehydration reaction
this means energy must be added in
order for the reaction to occur
Putting
together
HydrolysisBreaking
apart polymers
 Breaking apart polymer
Hydrolysis(break
w/ water)
Adding water
molecule
Adding water molecule
HydrolysisBreaking
apart polymers
 Breaking apart polymer
Hydrolysis(break
w/ water)
Adding water
molecule
Adding water molecule
HydrolysisBreaking
apart polymers
 Breaking apart polymer
Hydrolysis(break
w/ water)
Adding water
molecule
Adding water molecule
HydrolysisBreaking
apart polymers
 Breaking apart polymer
Hydrolysis(break
w/ water)
Adding water
molecule
Adding water molecule
Creating MonomersHydrolysis reaction
this gives off energy when this happens
breaking
up
explain
to your partner what is
Hydrolysishappening
 Breaking apart polymer
Adding water molecule
Macromolecules
(large molecules):
Carbohydrates
Lipids
Proteins
Nucleic Acids
Carbohydratesfunctions:
Fuel - stores energy
Building material - >
in plants = cellulose (cell wall)
in animals = chitin (insect/
lobster covering)
Carbohydrates- types:
1)Monosaccharides
Single Sugar
Monosaccharides
Structure: Single Sugar
Function: Fuel for cell work
ex. glucose - blood sugar
fructose - fruit sugar
lactose - ??
Monosaccharides structure:
multiple of CH2O
ex. glucose C6H12O6
Disaccharides
Two sugar monomers joined
by dehydration synthesis
Disaccharides
Two sugar monomers joined
by dehydration synthesis JOIN / SPIT
OH-
Disaccharides
Two sugar monomers joined
by dehydration synthesis
ex. sucrose - table sugar
Polysaccharides
Many monomers
Polysaccharides
Many monomers
Functions:
•1) Energy storage=
•starch (plant)
•glycogen (animal)
Polysaccharides
Many monomers
Functions:
•1) Energy storage=
2) Structural support = cellulose
Polysaccharides
2)
Structural
support =
cellulose
Macromolecules
(large molecules):
Carbohydrates
Lipids
Proteins
Nucleic Acids
LipidsTypes:
1) Fat~ triglyceride
2) Phospholipid~ cell membranes
3) Steriod
4) Wax
LipidsStructure = have a higher ratio of
C & H than Oxygen
Therefore, are they
polar or nonpolar?
They
HATE
water
Lipids- (hydrophobic)
1) Fats (triglyceride) functions:
-energy storage
-cushion internal organs
-insulation
Types of Lipids: Fats- structure
1 Glycerol
Fatty acid chain = hydrophobic
•Energy storage
•Cushion
Types of Lipids: Fats- structure
+3 fatty acid
 Glycerol
chains
Fatty acid chain = hydrophobic
•Energy storage
•Cushion
http://www.youtube.com/watch?v=Eu5j_Us8uI&safe=active
2)Phospholipids- structure
1 hydrophilic head
2 hydrophobic tails
2)Phospholipids- structure
1 hydrophilic head
2 hydrophobic tails
3) Steroids4 Fused (connected) “rings”
cholesterol, testosterone, estrogen
4) WaxLong CH2 chain
Macromolecules
(large molecules):
Carbohydrates
Lipids
Proteins
Nucleic Acids
ProteinsMonomer = amino acid
Polymer of amino acids =
polypeptides-
Proteinsfunction depends on shape:
1) support
2) structure
3) enzymes
Amino Acids = monomer
20 types
Amino Acids
H
amino
group
C
NH2
Carboxyl
COOH
R
(VARIABLE)
20 types
Amino Acids
H
amino
group
20 varying
molecules
C
R
carboxyl
20 types
Proteins- precise sequence of amino acids.
amino -     - carboxyl
group
group
Sequence of amino
acids determines
HOW the protein
works
Shape
determine
s how the
protein
works
Macromolecules
(large molecules):
Carbohydrates
Lipids
Proteins
Nucleic Acids
Nucleic AcidsDNA
RNA
Programs ALL organism function
Nucleic AcidsComposed of: nitrogen base,
sugar,
phosphate group
= NUCLEOTIDE
DNA
RNA
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