LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – BIO TECHNOLOGY THIRD SEMESTER – APRIL 2007 IB 05 BT 3901 - MEDICAL MICROBIOLOGY Date & Time: 26/04/2007 / 9:00 - 12:00 Dept. No. Max. : 100 Marks PART- A (20 marks) Answer ALL questions. I. Choose the correct answer. (5x1=5 marks) 01. Match A. Metchnikoff B. Lister C. Ehrlich D. Ricketts with i. Chemotherapy ii. Typhus Fever iii. Phagocytosis iv. Carbolic acid a. A-III B-IV C-II D-I b. A-III B-I C-IV D-II c. A-III B-IV C-I D-II d. A-III B-II C-IV D-I 02. Statement A : Portal of entry refers to the mechanism by which pathogens come out of the host. Statement B : All pathogens have the same portal of entry: a. Statement A is correct but Statement B is incorrect b. Statement B is correct but Statement A is incorrect c. Both A and B are correct d. Both A and B are incorrect 03. An example of a synthetic chemotherapeutic agent is : a. Sulfonamide b. Penicillin c. Ampicillin d. Streptomycin 04. Which one of the following disease is caused by a fungus? a. Herpes b. Cholera c. Histoplasmosis d. Typhoid 05. Malaria is caused by a : a. Protozoan b. Bacterium c. Mosquito d. Virus II. State whether the following are True or False ; If false, state the reason : (5x1=5 marks) 06. Hanging drop preparation is used to stain bacteria. 07. Communicability is otherwise called transmission of disease. 08. Interferon is a nonspecific antibacterial agent present in blood. 09. Amoebiasis is an airborne infection of man. 10. The causal organism of AIDS is a RNA virus. III. Complete the following. (5x1=5 marks) 11. Gram staining is also called as ___________ staining. 12. ________ are toxins which are released outside the bacterial cell. 13. _________ are the main blood cells involved in host’s defenses. 14. ___________ is caused by Entamoeba histolytica. 15. The causal organism of typhus fever is _________ prowezekii. IV. Answer the following each within 50 words. (5x1=5 marks) 16. What is cold sterilization? 17. What is a reservoir? 18. Distinguish between active and passive immunity. 19. Name the causal organism and one symptom of Trichomoniasis. 20. Write two points about madcow disease. PART-B (5x8=40 marks) V. Answer any five of the following, each within 500 words only. 21. Give an account of gaseous chemosterilizers. 22. Distinguish between transient and resident flora. Mention their role. 23. Give an outline of immunity, mentioning the salient aspects. 24. Discuss the causal organism, morphology, symptoms and control measures of Diphtheria. 25. Write about the symptoms, treatment and control of chickenpox. 26. Expand the following with a footnote each: a. HBV b. DPT c. ATS d. AFB 27. Write about dermatophytoses. 28. Define the term ‘antibiotic’. Mention the source, spectrum of activity and mode of action of any 3 antibiotics. PART-C (2x20=40 marks) VI. Answer the following, each within 1200 words only. 29. a. Write an essay on physical methods of control. or b. What are antigen-antibody reaction? Discuss any two of them. 30. a. Give a detailed account of AIDS. or b. Explain the causal organism, symptoms, treatment and control of TB. ---- 2