LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION - ZOOLOGY THIRD SEMESTER – November 2008 ED 35 BT 3901 - MEDICAL MICROBIOLOGY Date : 14-11-08 Time : 9:00 - 12:00 Dept. No. Max. : 100 Marks PART A (20 marks) Answer All questions I. Choose the Correct Answer 01. Match A) Jenner with (5 x 1 = 5 marks) B) Flemming i) Chemotheraphy ii) Vaccination C) Ehrlich D) Koch iii) Postulates iv) Penicillin. a) A-ii, B-iv, C-i, D) iii b) A-ii, B-iv, C-iii, D) i c) A-ii, B-iii, C-iv, D) I d) A-ii, B-i, D) iv C-iii, 02. Statement A: Lecithinase is otherwise called spreading factor. Statement B: It is found in snake venom. a. Statement A is correct, but B is incorrect b. Statement A is incorrect, but B is correct c. Both A and B are correct d. Both A and B are incorrect 03. Which antibiotic inhibits bacterial protein synthesis? a. Penicillin b. Polymyxin c. Streptomycin d. Griseofuluin c. Cholera d. Diphtheria c. Varicella d. Plasmodium 04. Corynebacterium is the genus causing: a. TB b. Influenza 05. Typhus fever is caused by: a. Rickettsia b. Salmonella II State whether the following are True or False. If false, given reason (5 x 1 = 5 marks) 06. Antiseptic is a chemical applied on living tissues. 07. Portal of entry is the same for all pathogens. 08. Agglutination is the most striking of all test - tube ag-ab reactions. 09. Hepatitis is caused by a DNA virus. 10. AIDS is an endemic disease. III. Complete the following 11. Tyndallization is also called as ______________ (5 x 1 = 5 marks) _______________. 12. The two types of carriers are _____________ and ________________. 13. _________are antiviral _________ produced by host cells in response to viral infection. 14. ___________ _____________ is the causal organism of candidiasis. 15. The vector of malarial parasite is _____________ _____________ mosquito. 1 IV. Answer all, each in about 50 words (5 x 1 = 5 marks) 16. Distinguish between sterilization and disinfection 17. Mention any two roles of resident flora. 18. What is Phagocytosis? Who coined this term? 19. Name any two symptoms of Influenza. 20. Write down the two vaccines administrated for Polio. PART B (5 x 8 = 40 marks) Answer any FIVE, each within 350 words only. Draw diagrams and flowcharts wherever necessary. 21. Classify bacteria based on Gram staining. 22. Write down the 7 capabilities of a pathogen. Elaborate any one of them. 23. Discuss the importance of blood as an internal defense mechanism. 24. Explain the causal organism, symptoms and treatment of TB. 25. Name the causal organism of chickenpox. Write about the stages of chicken pox. 26. Expand the following with a foot note each: a) HEPA b) URT c) CFT d) PID 27. Define the following: a) Dermatophytoses b) Credes method c) Commensalism d) Complement 28. Distinguish between: (any one difference) a) Causal organism of syphilis and gonorrhea b) Symptoms of tetanus and Typhus fever c) Moist heat and dry heat d) Pyogenic and pyrogenic infection PART C (2 x 20 = 40 marks) Answer the following, each within 1500 words only. Draw diagrams and flowcharts wherever necessary. 29. a) Discuss the importance of the following in the control of microbes: i) Radiation ii) Filtration iii) Phenol iv) Halogens (OR) b) Give an account of virulence factors. 30. a) Write about the causal organism, symptoms, lab diagnosis, treatment and prevention of Cholera. (OR) b) Write notes on: a) Mode of transmission and prevention of AIDS. b) Mode of infection (types) and treatment of Anthrax. ********** 2