LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – ZOOLOGY
THIRD SEMESTER – NOVEMBER 2010
BT 3901 - MEDICAL MICROBIOLOGY
Date : 09-11-10
Time : 9:00 - 12:00
Dept. No.
Max. : 100 Marks
Part A
Answer All questions
I Choose the Correct Answer
01. Match A) Electron accelerator B) Autoclave C) Hot air oven D) Steam Arnold
With i) Dry heat ii) Moist heat iii) Cathode rays iv) Tyndallization
a) A-iii, B-i, C-iv, D) ii
b) A-iii, B-i, C-ii, D) iv
c) A-iii, B-iv, C-i
D) ii
d) A-iii, B-ii, C-i, D) iv
02. Which among the following is the prominent resident flora of vagina?
a. Streptococcus
b. Lactobacillus
c. E. coli
d. Staphylococcus
03. Statement A: The term chemotherapy was coined by Ehrlich.
Statement B: Antibiotics come under biosynthetic chemotherapeutic agents.
a) Statement A is correct, but B is incorrect
b) Statement A is incorrect, but B is correct
c) Both A and B are correct
d) Both A and B are incorrect
04. Typhoid fever is caused by:
a. Bacterium
b. Protozoan
c.Virus
d. Fungus
05. Pick out the vector borne disease from the following:
a. Tetanus
b. Poliomyelitis
c. Malaria
d. Chicken pox
II State whether the following are True or False. If false, given reason
06. Disinfection refers to the complete destruction of all forms of microbial life.
07. Human disease caused by a pathogen with animal reservoir is called zoonosis .
08. Interferons are nonspecific antibacterial proteins.
09. Rice water stool is the most prominent symptom of amoebiasis.
(20 marks)
(5 x 1 = 5 marks)
(5 x 1 = 5 marks)
10. Anthrax is caused by a Gram positive, spore forming Bacillus.
III. Complete the following
(5 x 1 = 5 marks)
11. The Term vaccination was coined by ____________ in honor of _____________.
12. ___________ ____________ refers to the microbes which remains in/on our body
only for a short time.
13. The source of Streptomycin is ____________ _____________.
14. Trichomoniasis is caused by___________ _____________.
15. Tetanus is commonly called __________ because of ___________ spasms in the jaw.
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IV. Answer the following, each in about 50 words only
( 5 X 1 = 5 marks)
16. What is Credes method?
17. Name the two types of carriers of pathogen.
18. Distinguish between active and passive immunity.
19. Mention the causal organism of TB. What type of bacterium it is, based on staining
reaction?
20. Enlist any two genera of Dermatophytoses.
PART B
(5 x 8 = 40 marks)
Answer any five, each within 350 words only. Draw diagrams and flowcharts wherever necessary.
21. Mention the contribution of any eight scientists to the field of medical microbiology.
22. Distinguish between exotoxins and endotoxins.
23. Give an account of complement fixation tests.
24. Discuss the causes, signs and symptoms of diphtheria.
25. Briefly explain the structure of the causal organism of AIDS. Add a note on its
prevention.
26. Expand the following with a foot notes each:
a) LTH
b) NMF
c) BCG
d) HBV
27. Define the following:
a) Impetigo b) Cold sterilization c) Portal of entry d) Acquired immunity
28. Distinguish between: (any one difference)
a) Morphology of the Causal organisms of Typhoid and Cholera
b) Symptoms of poliomyelitis and Chicken pox
c) Antiseptic and disinfectant d) Alpha and betahaemolysis
PART C
(2 x 20 = 40 marks)
Answer the following, each within 1500 words only. Draw diagrams and flowcharts wherever necessary.
29. Give an account of any three physical and any two chemical agents used in the control
of microbes
or
b) Write notes on
i) Role of intestinal flora
ii) Any five antibiotics – source and mode of action
30. a) Compare and contrast Syphilis and Gonorrhoea based on causal organism, incubation
period, symptoms and treatment.
or
b) Explain the following:
i) Disease cycle of Malaria
ii) Types of Anthrax
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