Topics • Interphase • Mitosis • Cytokinesis Interphase • Cells are in interphase about 90% of the time. Interphase • During this phase chromosomes replicate. Mitosis • Prophase • Metaphase • Anaphase • Telophase Prophase • The nuclear membrane breaks down Prophase • Nucleoli gradually disappear Prophase • Chromosomes become visible as the chromatin condenses Prophase • Each chromosome appears as two sister chromatids, linked together, at the centromere. Metaphase • The chromosomes arrange themselves at the center of the cell (on the equatorial plane). Anaphase • Sister chromatids separate and are pulled to opposite ends or poles of the cell. Anaphase • The chromosomes appear V shaped. Telophase • The nuclear membrane begins to reform. Telophase • Nucleoli begin to reappear. Telophase • A furrow appears that contricts the cytoplasmic mass. Cytokinesis • The cell divides in half. • Result: Two identical daughter cells.