Chapter 5 Tissue Outline Definition: Tissue is a group of similar cells and cell products that arise from the same region of the embryo and work together to perform a specific function. Tissue sections: histological sections and can be longitudinal, cross section or transverse section and oblique section. See page 143. Four types of tissues---epithelial, connective, muscle, nervous 1. Epithelial tissue function: protection, secretion, excretion, filtration and sensation. Epithelium: - Covering and lining epithelium - Glandular epithelium Characteristics of epithelium: - Closely packed cells - Cell to cell contacts---tight junctions and desmosomes - Polarity--- apical and basal surface - Supported by connective tissue Classification of epithelium: On the bases of structure (shape of cells) and function (number of layers) Number of layers: One layer of cells--- simple More than one layer of cells--- stratified Shape of the cells: Squamous---flat, scale like --Cuboidal---cube or box like Columnar---tall and column like Combined classification: function with structure a). Simple squamous epithelia --- for absorption, secretion and filteration e.g. wall of glomerular capsule. Air sacs Special names to certain simple squamous epithelia - Endothelium--- inner covering e.g. lymphatic vessels, blood vessels - Mesothelium --- middle covering e.g. in serous membranes lining of body cavity b). Simple cuboidal epithelia --- secretion and absorption e.g. kidney tubules c). Simple columnar epithelia --- absorption and secretion e.g. lines the digestive tract--some modified into goblet cells d). Pseudostratified columnar epithelia --- vary in height but all rest on the basement membrane e.g. trachea e). Stratified squamous epithelia --- wear and tear, protection e.g. skin f). Stratified cuboidal epithelia --- secretion e.g. sweat glands g). Stratified columnar epithelia --- male urethra h). Transitional epithelia --- stretch e.g. lining of hollow urinary organs--- basal cells cuboidal or columnar, apical cells --- squamous Glandular epithelia: Exocrine glands --- with ducts Endocrine glands --- ductless 2. Connective tissue Definition: Mostly binds one organ to each other. Connective tissue functions: binding organs (tendon bind muscle to bone); support ( bones support the body, cartilage support the ear); physical protection (cranium, ribs); immune protection(connective tissue cells attack foreign invaders) ;movement (bones as lever system of body; storage (fat); heat production (metabolism of brown fate generate heat in infant and children) transport (blood transport gases). See page 150-151. characteristics: common origin--- mesenchyme extracellular matrix --- mostly made up of ground substance Structural elements: Ground substance-proeoglycan, glycosaminoglycan (chondroitin sulphate, hyaluronic acid) Fibers-collagen, reticular and elastic. Cells-fibroblast, macrophages, leukocytes, mast cells, plasma cells, adipocytes. Types of connective tissue: i) Embryonic connective tissue: mesenchyme ,mucous connective tissue ii) Connective tissue proper--- two subclasses a) Loose connective tissue b) Dense connective tissue-dense regular ( collagen fibers closely packed in regular manner and dense irregular (bundles of collagen fibers arranged irregularly (most of dermis) Loose connective tissue Areolar Adipose Reticular Dense connective tissue Cartilage Bone Blood Covering and lining membrane cutaneous mucous serous 3. Nerous tissue: - Neurons - neuroglia 4. Muscle tissue: - Skeletal - Cardiac - smooth