Titration of Aspirin Lab
Data Table:
Trial
Concentration
of NaOH (M)
1
Initial
Final
Volume
Volume
Reading
Reading
NaOH (mL) NaOH (mL)
Volume of
NaOH
used to
Titrate
(mL)
Volume
NaOH (L)
Concentration
of Aspirin (M)
Mass of
Aspirin
(g)
0.100
2
0.100
3
0.100
Average
Post Lab Calculations:
1. Write the balanced equation for the reaction of aspirin (acetylsalicylic acid) and sodium hydroxide.
2. For each trial, calculate the concentration of aspirin and the mass of the aspirin then calculate the average.
Show your work for one trial.
3. According the label on the bottle of aspirin, each tablet contains 325mg of aspirin. Calculate the percent error
using your average mass of aspirin from the lab.
Post-Lab Analysis:
1. What is the purpose of the indicator, phenolphthalein, in an acid-base titration?
2. How could the insoluble white binder affect the detection of the end point in this experiment?
3. The parietal cells of the stomach secrete hydrochloric acid at a concentration of 0.16M. Tums is a common
antacid used to neutralize stomach acid which can cause heartburn and indigestion. One tablet contains 0.05M
of calcium carbonate in a 0.005L tablet. How much stomach acid will one Tums tablet neutralize?