Meiosis Meiosis • Sexual Reproduction • The creation of four new cells with ½ (half) the number of chromosomes of the parents. – Example: Humans have 46 chromosomes each new cell only has 23 chromosomes • Sperm (23) + Egg (23) = 46 chromosomes Important words to know related to meiosis: • Homologous chromosomes= – 2 sets of chromosomes (4 chromosomes total) that have similar DNA sequences and come from separate parents. – Ex: one set comes from the mother and the other set comes from the father. Important words to know related to meiosis: • Diploid= means “two sets.” Cell that contains both sets of homologous chromosomes. – Represented by 2N • Haploid= means “one set.” Cell that contains one set of chromosomes. – Represented by N The stages of Meiosis Interphase 1 • Meiosis 1 • – Prophase 1 – Metaphase 1 – Anaphase 1 – Telophase 1 • Meiosis 2 – Prophase 2 – Metaphase 2 – Anaphase 2 – Telophase 2 Interphase 1 • Chromosomes Double • Organelles duplicate (make copies) • Cell grows Prophase 1 • Homologous chromosomes move together to form Tetrads – Tetrad= pairs of chromosomes • Nuclear Envelope (Membrane) disappears • Centrioles move apart forming Spindle Fibers Crossing Over • Occurs during meiosis. 1.Homologous chromosomes form a tetrad. 2.Chromatids cross over one another. 3.The crossed sections of the chromatids are exchanged. Crossing Over Metaphase 1 • Homologous pairs (tetrads) line up at the center of the cell • Centrioles are at the poles attached to each sister chromatid by spindle fibers Anaphase 1 • Homologous chromosomes move to poles of the cell • Sister chromosomes remain attached at the centromere • • • • Telophase 1 & Cytokinesis Homologous chromosomes move to poles Nuclear envelope reforms (sometimes) Spindle apparatus disappears Cells divide into TWO new cells (Cytokinesis) Meiosis 1 Interphase I Meiosis I Prophase I Metaphase I Anaphase I Telophase I and Cytokinesis Prophase 2 • Nuclear envelope disappears (if there) • Spindle fibers reform Metaphase 2 • Sister Chromatids line up at the center of the cell • Centrioles at the ends of the cells Anaphase 2 • Sister chromatids separate and move towards the poles • • • • Telophase 2 Nucleus reforms Spindle fibers disappear Cytokinesis 4 NEW CELLS FORM WITH ½ THE ORIGINAL NUMBER OF CHROMOSOMES Meiosis 2 Telophase I and Cytokinesis I Meiosis II Prophase II Metaphase II Anaphase II Telophase II and Cytokinesis