Part 1- Diffusion and Osmosis I. The Cell Membrane The cell membrane controls what moves into and out of the cell A. Composed of a lipid (fat) bilayer (two part layer) made of molecules called phospholipids B. The hydrophobic (“water hating”) tails of the phospholipids move away from the water in the cytoplasm, the hydrophillic (“water loving”) heads are attracted to the water of the cytoplasm or external environment of the cell II. Proteins in the membrane Proteins are embedded in the lipid bilayer and have several functions: A. They serve as cell markers to identify the cell B. They serve as transport proteins for specific molecules Proteins in the Membrane III. Homeostasis Homeostasis - maintaining stable conditions inside the cell, even if external conditions are changing A. Cells must maintain homeostasis or they will die B. Examples: sweating/shivering or a room thermostat IV. Diffusion Diffusion- movement of molecules from areas of higher concentration to areas of lower concentration (from where there are more to where there are less) until the concentrations are equal A. diffusion naturally takes place due to Brownian motion (random movement) of molecules B. water, oxygen, and carbon dioxide are small molecules and diffuse easily across the Membrane C. Examples: oxygen moving from lungs into red blood cells, food molecules moving from the small intestine into the blood stream, waste molecules of urea moving from the blood into the kidney Diffusion V. Osmosis and Isotonic Situations A. Osmosis - movement of water molecules across a membrane (such as a cell membrane or artificial membrane) B. Isotonic - (iso- “same”) the concentration of dissolved substances (solute) is the same outside the cell as inside the cell Result: there is no net (overall) movement of water molecules (an equilibrium) VI. Hypertonic Situations and Plasmolysis Hypertonic - (hyper- “above”) the concentration of dissolved substances (solute) is greater outside the cell than inside the cell Result: more water molecules leave the cell than enter the cell and the cell will shrink A. Animal cells will shrivel up B. Plant cell membranes will shrink and pull away from the cell wall in plasmolysis VI. Hypotonic Situations and Turgor Pressure Hypotonic - (hypo- “below”) the concentration of dissolved substances (solute) is lower outside the cell than inside the cell Result: more water molecules enter the cell than leave the cell and the cell will swell A. Animals cells will burst if the pressure is too great B. In a plant cell the pressure pushes against the cell wall and keeps the plant from wilting (turgor pressure) Part 2- Facilitated Diffusion and Active Transport Larger molecules such as polysaccharides, proteins, and lipids cannot diffuse across the membrane because they are too big. I. Passive Transport Passive transport - transport which does not require energy from the cell because molecules move with the concentration gradient (from high to low concentrations) A.(Simple) Diffusion B. Facilitated Diffusion - movement of molecules from areas of higher concentration to areas of lower concentration using protein channels 1. Each channel transports a specific type of molecule such as sugar or sodium ions (Na+) 2. The channels may open in response to signals from the cell C. Because the cell membrane is controlling what enters and leaves the cell, it is called semipermeable or selectively permeable II. Active Transport Active Transport - transport which does require energy from the cell because molecules move against the concentration gradient (from low to high concentrations) A. Transport proteins pump molecules (such as Na+, K+, and Cl-) across the membrane B. The energy comes from ATP (more on this later) C. Example - the sodium-potassium pump III. Transporting Large Molecules A. Endocytosis - process of taking in molecules from the environment B. Phagocytosis - “cell eating” taking in solid particles C. Pinocytosis - “cell drinking” taking in drops of liquid D. Exocytosis - process of getting rid of molecules by merging a vacuole or vessicle with the cell membrane The End!