The Endocrine System The endocrine system uses chemical messengers called hormones to transfer information around your body. Hormones are made in special organs called endocrine glands. The major glands that make up the human endocrine system are the: hypothalamus, pituitary gland, thyroid, parathyroids, adrenals, pineal body, reproductive glands (ovaries and testes), and the pancreas. The pituitary gland is the master gland as it makes hormones but also tells many other endocrine glands to release their hormones as well. The pituitary gland receives messages from the hypothalamus in the brain so it provides the link between the nervous system and the endocrine system. Hormones travel all around your body in the blood but only act on target cells that have the right receptor. The hormone binds to the receptor like a key fits in a lock then it triggers changes in the cells behaviour. Several hormones come into play as you exercise. Glucogon and insulin are produced by the pancreas and regulate glucose levels and therefore the amount of energy available for muscle contractions. Antidiuretic hormone (ADH) is produced by the posterior lobe of the pituitary gland and helps control body water balance through its effect on the kidneys and urine output. Aldeosterone is produced by the adrenals and also helps regulate salt and water balance. The adrenals also produce adrenaline which increases blood pressure and heart rate. If you have been exercising for an extended period of time, you will appreciate the effects endorphins which are secreted by the pituitary gland and act on the nervous system to reduce sensitivity to pain (think runner’s high!). Some hormones including testosterone, epitestosterone, human growth hormone and erythropoietin have been identified as performance-enhancing drugs and may be used by athletes in an attempt to improve performance in their chosen field. The Endocrine System Label the organs of the endocrine system on the diagram below. The Endocrine System V C O G Q V T G P Z L P R Z A S T I T M T I A J X X N V I K 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. R V M K A E P L X S V D S U M A L A H T O P Y H L D P F Y Y H J Y Z P I W U Y U S F P F P V S E I R A V O T O J L V W J H U J F B D B U A H N M V F B E P G I S Y E C W V Q X H W P H U V F K T S F W B C R D N K I W L W Z V Q P A T U M Q V W G I R N X R S G I A H C L P X D B U P Q K Y C V K V B W Y N J Y P P K R M L X X S J W Q K T S U X Z S U I L R Z A Q Q W B E V Q Q Q M W M N H C P M Q R S F Y S B M F P E L R O N P Y N D M N S A N I G G V U Z N R M G A U L D O Q E J L L Q R C D L Z W L E H E E J J G G W Q M L W H V F M P R X V V G E R O W G O O P C C Q B U D D O S R O I R E T S O P Y R T T Y X C P D Z R K K W B Y U S V Z L A W I H S P Y R W P M E M X X R U V O S Y A H N C I T M D O E N X B O D J D C S T W U U F I G D R A I D S A E R C N A P K C M A N R S G Q B T C W D H N N M W O Y N C Q R Y A N R S Y K E X C E M K A A Y F X B I E D N Z N K R X O X L J X E A I A C G T F A O R F P D T N E G S X X V T L E U G H T N W O Y D W S H L V G N A P I F Y Q L T L D Q Z B J Y X A I L Z N K N E E D M E Z P E J R U K Y A J O M S T Z R V F L W O X V T T H E H T R F B Q S R J N U N T V T N R A B D A C A V D Q Z R O Q C R P F K O J C B L M D W T X A T Z A N H P V T M S T S C E G C V N X O X D Z R D S A K Y I O Y E N I C L K T N T L L B J J D P K N B I T S F H V R U O X R U O E I P R X E R L X N B C L Q Q Q L T E A P A L T C E D B N T Q F Q E R A S B E Q Y V W M N I A K Z K D C I E O A W T B Y Y O P O Y O O Z J O C J P Z W L N Z U L F P P E M D H Q M V U M N E C E X Z B U R U U G O P E H B Q M P Q R A U Z T S K M E R R O D W Y A V X U G D Z X R X G V R C P W B O F I Z S D Y D W M U H B U D X I D V R L D A Y S Chemical messengers that transfer information around your body. Organs where hormones are made. This gland is referred to as the master gland. This part of the brain sends messages to the master gland. Hormones only act on these. These secrete the female sex hormones. This gland secretes hormones that regulate glucose levels. These secrete the male sex hormones. These glands are found on the top of the kidneys. This lobe of the pituitary gland is responsible for the production of ADH. Along with ADH this hormone helps regulate salt and water balance. This hormone increases blood pressure and heart rate. Responsible for runner's high. A hormone binds to this. C I R C S Y I W Q B F J G C A O Z T N N F Y S M W K A K X H J F D R O T P E C E R V K Q B Y F Q B O H H T N Z S H O R P The Nervous System Your nervous system controls and co-ordinates all parts of your body. It can be divided into two parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The central nervous system (CNS) is made up of the brain and spinal cord. It acts as the control centre, receiving messages from all parts of the body then sending messages to tell different parts of the body how to respond. The brain and spinal cord are surrounded by three layers of connective tissue called the meninges. The brain is protected by the cranium and the spinal cord is protected by the bony spinal column. The peripheral nervous system (PNS) connects the CNS to the rest of the body. The nerves in the CNS fall into two categories, sensory neurons and motor neurons. Sensory or afferent nerves carry information to the CNS, while motor or efferent nerves carry information away from the CNS. Interneurons are found only in the central nervous system where they connect sensory neurons to other neurons. They are also called connecting neurons. The motor nerves can be further divided into autonomic and somatic nerves. Autonomic (involuntary) nerves control things that you don’t think about – like your heart beating or your small intestine working. Somatic (voluntary) nerves control movements that you are aware of – like your skeletal muscles, bones and sensory organs. We can further divide the autonomic nerves into two types (sympathetic and parasympathetic). Sympathetic nerves generally excite or speed up an organ in response to stimuli (e.g. heart beating faster after a fright) while parasympathetic nerves general retard or slow down an organ after it has responded (e.g. slow heart beat back to normal). The Nervous System The CNS and PNS are made of neurons or nerve cells. They are special cells that transmit and receive messages in the form of electrical impulses. Neurons come in different shapes and sizes, but they all have 3 distinct parts: 1. Cell body or soma – contains the nucleus and all the things needed for the neuron to keep functioning (the nucleus is the ‘brain’ of the cell). 2. Dendrites – these small branches stick out from the cell body. Their job is to carry information to the cell body. 3. Axon – also called the nerve fibre, this part of the neuron carries information away from the cell body. The end of the nerve fibre is called the terminal end. Most axons are wrapped in a sheath called the myelin sheath. The myelin sheath is made up of glial cells referred to as Schwann’s cells. Gaps in the myelin sheath are called Nodes of Ranvier. Neurons communicate with other cells by means of chemicals, known as neurotransmitters. In the nervous system, the passage of a nerve impulse along one neuron involves electrical changes (an action potential), while the transmission from cell to cell involves diffusion of neurotransmitters across the synapse or gap between the axon terminals of the transmitting neuron and the dendrites of the receiving neuron. As nerve impulse travels, it changes from an electrical message (within the neuron) to a chemical message across the synapses, then back to an electrical message again in the next neuron. Painkilling drugs work by blocking the release of neurotransmitters into the synapses. The Nervous System Label the neuron below using the words in the box below. soma nucleus dendrites axon myelin sheath terminal end Nodes of Ranvier The Nervous System Down 1. these small branches stick out from the cell body of a neuron. 3. the gap between the axon terminals of a transmitting neuron and the dendrites of the receiving neuron. 4. the autonomic nervous system is called autonomic because the organs it activates or retards function ________________ of our control. 5. neurons use these chemicals to communicate with other cells. 9. electrical changes within an axon are referred to as an ________________ potential. 11. gaps in the myelin sheath are referred to as Nodes of ______________. 12. the somatic nervous system controls _______________ muscles. 13. breathing and salivation are functions controlled by this branch of the PNS. 15. motor neurons are also called ________________ neurons. 16. three layers of connective tissue surrounding the brain and spinal cord. 17. _____________ neurons carry information away from the CNS towards your muscles, skin, internal organs and glands. 18. _______________________ nerves carry information from the internal organs or outside environment to the CNS. Across 2. PNS stands for this. 6. the myelin sheath is composed of this type of cell. 7. These work by blocking the release of neurotransmitters into the synapses. 8. Another name for the cell body of a neuron. 9. sensory neurons are also called ________________ neurons. 10. also known as the nerve fibre. 14. This type of neuron is only found in the CNS. 19. your nervous system controls and ________________ all parts of your body. 20. CNS stands for this.