Chapter 3 What is another name for Neuron? nerve cells Nerve impulse in the form of electrochemical impulse runs through our entire body and communicate with each other (glands, muscles) Regulates our internal functions Learn new behavior or information - N.S. Registers experience and changes to accommodate its storage Why do you think the transparency show the anatomy of two neurons instead of one? Because the function of the neurons is to communicate with one another. TRANSMITS IN ONE DIRECTION Chapter 3 EACH NEURON HAS: (pg. 54) CELL BODY – produces energy that fuels cell activity AXON – Carries messages away from the cell body Axon has MYELIN - white fatty substance insulates and protects axon MYELIN SHEATH - protects the axon and helps speed up the transmission of the message DENDRITES - receives information from other neurons and pass information through the cell body Leafy fibers branching out – contain neurotransmitters AXON TERMINALS pass messages from one neuron to the dendrites of the next neuron. Neurotransmitters are chemicals stored in sacs in the axon terminals. When released chemicals cross the synapse to reach the next neuron. SYNAPTIC GAP - space between axon terminal and membrane of the postsynaptic cell (dendrite) SYNAPSE - the space between 2 cells that separates the axon terminals of sending neuron from the dendrites of its receiving neuron. New synapse can develop between neurons not previously connected when learn something new Chapter 3 NEURON IMPULSE TRAVELS ONLY IN ONE DIRECTION and takes a fraction of a second. Pain is transmitted through SENSORY NEURONS which carry information received by senses to CNS MOTOR NEURONS - carry information from CNS to muscles / glands INTER NEURONS - specialized nerve cells within the brain and spinal cord that communicate internally and intervene between sensory inputs and motor inputs Chapter 3 NEUROTRANSMITTERS Neuron releases only ONE type of neuron transmitter. Each type of neurotransmitter has a specific structure and fits into a receptor site on the next neuron like a key fits a lock. 1. ACETYLCHOLINE involves in the control of MUSCLES as well as AROUSAL, MEMORY, MOTIVATION (motor neurons - spinal cord stimulates muscles) Patients who have low levels of acetylcholine may help Alzheimer disease if use a chemical stimulate enhances memory Patients who have high levels lead to spasms and tremors 2. DOPAMINE involved in MOTOR BEHAVIOR, LEARNING, REINFORCEMENT, maintain FOCUS and ATTENTION deficiency - plays role in Parkinson’s (tremor, uncoordination) excess - contribute to PD - schizophrenia Chapter 3 NEUROTRANSMITTERS 3. NORADRENALINE involved in preparing the BODY FOR ACTION, CONTROL, ALERTNESS 4.**EPINEPHRINE (ADRENALINE) prepare body fight/flight **Hormone and/or neurotransmitter 5. NOREPINEPHRINE brings body back to slow level, calm tranquilizes body after stress 6. ENDORPHINS morphine; dulls pain; addictive pain suppressors brain response to pain 7. SUBSTANCE P - pain 8. SEROTONIN involved in EMOTIONAL AROUSAL & SLEEP, EATING DISORDERS, MOOD low levels - Depression, OCD (Prozac raise serotonin level to brain) Chapter 3 CENTRAL NERVOUS SYSTEM Made up of spinal cord and brain FUNCTIONS OF THE SPINAL CORD Spinal cord transmits messages between the brain and the muscle and glands of the body and is involved in reflex action. WHAT IS THE SPINAL REFLEX ACTION? - simple automatic response to something. ex. touching a hot stove; removal of hand is a spinal reflex by motor neuron pain does not cause the reflex - a person may register pain in head but pain not felt until after the hand has been removed. Ex. Blinking your eyes when lights are turned on in dark room because pupil automatically contracts when exposed to bright light; Ex. knee jerk - lower leg swings. Spinal reflex action DOES NOT receive its triggering message from the brain. Message goes from the sensory nerve to the spinal cord where special cells send a message to appropriate motor neurons which stimulate the muscles to take action. Chapter 3 PERIPHERAL NERVOUS SYSTEM Lies outside the central nervous system and is responsible for transmitting messages between central nervous system and all parts of the body. 3 MAIN DIVISION OF peripheral nervous system: 1.SOMATIC Nervous System • Transmits sensory messages to the central nervous system • Activated by touch, pain , changes in temperature, changes in body position • Enables us to experience sensations of hot/cold and feel pain/pressure • Also sends message to muscles and glands and helps maintain posture and balance. 2. AUTONOMIC Nervous System • occurring involuntarily or automatic • regulates the body’s vital functions: Heartbeat, Breathing, Digestion, and Blood Pressure, tear production Psychologists are interested in this Nervous System because OBSERVING RESPONSE when a person experiences something STRESSFUL in the environment. Chapter 3 PERIPHERAL NERVOUS SYSTEM 2 DIVISIONS of AUTONOMIC NERVOUS SYSTEM: 1. SYMPATHETIC Nervous System Activated when a person is going into an action, perhaps because of some stressful event. Prepares body either to confront the situation OR run away = FIGHT or FLIGHT response Ex. Attack by a dog Prepares body by suppressing digestion, increasing heart & respiration rates, elevates blood pressure Ex. POP QUIZ Sympathetic Nervous System is overly active in people who are anxious, including people with anxiety disorders. Over activity in SNS leads to high blood pressure, stroke, or heart problems Chapter 3 PERIPHERAL NERVOUS SYSTEM AUTONOMIC NERVOUS SYSTEM 2. PARASYMPATHETIC Nervous System Restores the body’s reserves of energy after an action has occurred. Heart rate and blood pressure are normalized Breathing slowed, digestion returns to normal REMEMBER: Sympathetic starts with S = STRESS Parasympathetic starts with P = PEACE PERIPHERAL NERVOUS SYSTEM 3RD DIVISION 3. ENTERIC Nervous System Meshwork of nerve fibers that innervate the viscera (gastrointestinal tract, pancreas, and gallbladder) Chapter 3 Brain functions effectively because intricate system of support and protection receives from other parts of body. Brain supported by nutrients and oxygen carried by blood vessels PROTECTED: By bones of the skull 3 layers of membranes (meninges) (meningeez) Fluids surrounds brain acts as a SHOCK ABSORBER LOCALIZATION OF FUNCTION - different parts of brain carry out different functions LATERALIZATION - some functions are carried out exclusively on one side of the brain, even for functions that take place on both sides of brain. Right/Left sides usually take care of different aspects of same functions. Chapter 3 VITAL FUNCTIONS HINDBRAIN heart rate blood pressure respiration balance/coordination MIDBRAIN Vision and hearing FOREBRAIN Complex function: thought & emotion Chapter 3 MAIN STRUCTURE HINDBRAIN - Basic body activities. Connects spinal cord with rest of body. Medulla directly connects the spinal cord with brain and helps regulate HEART RATE, BLOOD PRESSURE and BREATHING Cerebellum next to the medulla behind the brain stem (“little brain”); controlling balance & coordination, posture and maintaining equilibrium; allows us to walk and run without tripping Pons just above the medulla; Regulates BODY MOVEMENT (facial expression), ATTENTION, SLEEP, ALERTNESS, EATING (Produces chemicals help maintain sleep wake cycle) Chapter 3 Reticular Activating System (RAS) network of neurons extending from the medulla to forebrain (acts as a filter) Allows sensory information to enter brain i.e. sleep & arousal ex. AIR TRAFFIC CONTROL OF BRAIN regulates the flow of traffic ex. Teacher calls your name your RAS stimulates the higher brain centers that allows you to become alert. When asleep RAS restricts most environmental stimuli from entering your brain. Chapter 3 MIDBRAIN - important for hearing and sight; one place in brain where pain is registered Connects HINDBRAIN and FOREBRAIN Midbrain appears to function mainly as a relay station for messages coming into the brain. It also contains structures that play a role in seeing, hearing, and movement. Reticular Activating System - network of neurons extending from the medulla to forebrain; allows relevant sensory information such as AROUSAL or SLEEP to enter the brain. (air traffic control of the brain - regulates the flow of traffic); controls overall level of activity of central nervous system including WAKEFULNESS and SLEEP Ex. teacher calls your name - RAS stimulates higher brain centers that allow you to become alert. OR while sleeping your reticular formation restricts most environmental stimuli from entering your brain. Chapter 3 FOREBRAIN Biggest and most complex part It not only influences many of the basic life-support functions controlled by the midbrain and hindbrain but is also responsible for such higher level behaviors as thinking and speaking. Major structures of the forebrain: Thalamus • major sensory relay center to cerebral cortex • influences mood and movement. • Includes visual, auditory, touch stimuli. • Messages from these sense organs are channeled into the thalamus and from there are carried into specific parts of the forebrain for interpretation and action. Chapter 3 Hypothalamus (Size of pea) maintains stable internal environmental state involved in the motivation of such behaviors as: eating drinking, sexual drive, sleeping, and regulating body temperature, storage of nutrients. It also influences the pituitary gland which regulates biochemical reactions in the body and the part of the peripheral nervous system that regulates the internal body organs. pg.60 Chapter 3 Limbic System - autonomic response to SMELL, EMOTION, MOOD & other functions like sex, aggression, fear , pressure, pain. 4 important parts: hypothalamus, thalamus, hippocampus, amygdala The hypothalamus regulates motivation and emotion. The thalamus primarily relays sensory information to the cerebrum, the part of the brain that allows humans to think and store information. The hippocampus is involved in memory processing and learning. (Alzheimer’s disease patients often have low levels of acetylcholine in the hippocampus.) People with severe damage to this area can still remember, names, faces, events, before incident; can’t remember anything new. The amygdala is involved in anger and aggression. Automatic response to smell, emotion, mood, and other such functions: sex, aggression, fear, pressure and pain. Chapter 3 Basal Ganglia (base of forebrain) lie to the side of the thalamus and are important in voluntary motor responses (movement). The neuromuscular disorder Parkinson’s disease is associated with a breakdown of the neurotransmitter dopamine in the basal ganglia. If part of the limbic system is damaged people can recall old memories but don’t create new memories. May make you more passive/aggressive. Chapter 3 Cerebrum is the largest part of the forebrain; consists of two distinct structures called HEMISPHERES; Hemispheres are connected by the corpus callosum= bundle of neurons that keeps each hemisphere informed about what is happening in the other. Left Hemisphere controls the right side of the body and Right hemisphere controls the left side. Left Hemisphere - logical, analytical and verbal - reading, language, and understanding speech Right Hemisphere process nonverbal info and concerned with emotion, imagination, and artistic information. Most people are left dominant Chapter 3 Paul Broca - BROCA’s AREA located in Frontal lobe essential ability to talk (produces speech sounds) important for talking If Broca’s area damaged: APHASIA = (speechlessness) tends to expressive; language difficulty lies predominantly in sequencing and producing language (talking) Results from patients who suffered left hemisphere strokes and result brain damage. Produce language problems = APHASIA Chapter 3 Karl Wernicke later modified - Wernicke’s AREA toward back of temporal lobe processing and understanding what others saying important to listening If Wernicke’s area damaged: APHASIA = tends to be RECEPTIVE; difficulty understanding language Chapter 3 WHAT IS THE RELATIONSHIP BETWEEN THE CEREBRAL CORTEX AND THE CEREBRUM? Cerebral Cortex - is outer layer of the cerebrum (wrinkle ridges) ; controls overall level of activity of CNS Part of the brain used for THINKING - where messages from our SENSE ORGANS are interpreted and stored and where decisions about behavior are made. Has distinct sections/lobes that control different activities. (thought, voluntary movement, language, reasoning, perception) BRAIN STEM – area between thalamus and spinal cord structure within brain stem includes medulla, pons, RAS Functions: breathing, heart rate, blood pressure Chapter 3 LOBES – Frontal, Occipital,Temporal, Parietal Vision - Occipital - allow you to interpret what you see in the environment Hearing - Temporal - when you hear your teacher talking Somatosensory- Parietal - temperature, touch, pain Movement/memory - Frontal - when you remember past events or giving an answer to a question Left frontal more active than right frontal - tend to be more cheerful, sociable, self-confident Right frontal more active than left frontal - more stressed, frightened, upset by unpleasant things more suspicious and depressed Chapter 3 METHODS OF STUDYING THE BRAIN EEG - Electroencephalography - records general wave patterns of electrical activity CAT - Computerized Axial Tomography - x-rays reveal brain abnormalities; creates cross sectional pictures of brain only shows density of tissue of how much radiation absorbed [contrast] PET - Positron Emission Tomography - injects with radioactive glucose; examines brain activity MRI - Magnetic Resonance Imaging -use radio waves and magnetic fields to study chemical activity of brain cells. Chapter 3 ENDOCRINE SYSTEM Consists of glands that secrete substances called HORMONES into the BLOODSTREAM Hormones stimulate growth and many kinds of reactions - activity levels and moods Hormones affect behavior & emotional reactions Hormones have specific receptor sites. Hormones produced by several different glands. Glands include: PITUITARY GLAND = MASTER GLAND (lies under the hypothalamus) Stimulated by Hypothalamus - responsible for secretion of various hormones affect various behaviors a. Growth hormone - regulates growth of muscle, bone, glands b. Females to pregnancy and Production of milk THYROID ADRENAL TESTES & OVARIES Chapter 3 THYROID GLAND Produces THYROXIN affects body’s metabolism and converts food to energy ADRENAL GLAND Located above kidneys Outerlayer or cortex - secrete CORTICAL STEROIDS - increase resistance to stress and promote muscle development. Also produces ADRENALINE & NORADRENALINE These hormones arouse body enabling person to cope with stress Adrenaline - can intensify emotions such as fear & anxiety, raise blood pressure This hormone acts as a neurotransmitter as well Chapter 3 HEREDITY Transmission of characteristics from Parents to offspring plays key role in development of traits shown to be one factor involved in psych disorders (PD): anxiety, depression, schizophrenia, bipolar disorder, alcoholism KINSHIP STUDIES Common way to sort out roles that heredity and environment play determining a trait Kinship refers to degree how people related. Identical twins share 100% of genes Psych use info to determine how much a trait is influenced by genetics and how much by environment 2 Types of KINSHIP STUDIES 1. Twin 2. Adoptees