Group 22
Lindsey Robinson
Kingsley Onokalah
Maegan Joseph
Blake Meeks
Team Activity 9
In your Teams, prepare 3 multiple choice questions on the topic of Buffers and pH.
1. What is Buffer Capacity?
A. the amount of solution that can be added to a buffer and remain at a constant pH
B. measure of the buffers ability to resist pH
C. the pH range a buffer will have on a solution when added
D. the concentration of an acid required to make a basic solution neutral
2. Which of these values is within the normal range for Buffer Capacity (β)?
A. 0.2
B. 0.08
C. 7
D. 0.5
3. What does it mean if a solution has 2 different pKa values?
A. it has 2 electrons that can be donated
B. Itʼs pH range will be ±2
C. itʼs pH equals 2
D. It has 2 protons that can be donated
In your Teams, prepare 3 multiple choice questions on the topic of Solubility.
1. When calculating the dissolution rate, “C” is the:
a. Ionized concentration
b. Unionized concentration
c. Both a and b
d. Neither a or b
2. What is important in determining the ionization of a solution:
a. pH of the solution
b. pKa of the compound
c. Both a and b
d. Neither a or b
3. Stirring a solution causes the diffusion later (h) to _______; and the and the dissolution rate to
________.
a. Increase; Increase
b. Decrease; Increase
c. Increase; Decrease
d. Decrease;Decrease
Answers:
1. C
2. C
3. B
In your Teams, list 5 drugs from your “Top 200 Prescription Drug List” from PHA 371 – Practice of
Pharmacy that are weak acids and 5 drugs from this list that are weak bases. Identify the weak acid or
weak base functional group in each molecule.
Weak Acids:
1.
2.
3.
4.
5.
Levothyroxine Sodium – carboxylic acid
Atorvastatin Calcium – carboxylic acid
Naproxen – carboxylic acid
Warfarin Sodium - alcohol
Montelukast Sodium – carboxylic acid
Weak Bases:
1.
2.
3.
4.
5.
Metformin Hydrochloride - amine
Citalopram Hydrobromide - amine
Zolpidem Tartrate - amine
Sertraline Hydrochloride - amine
Duloxetine Hydrochloride - amine