Essential Idea Compounds of carbon, hydrogen and oxygen are used to supply and store energy. Understandings. • Monosaccharide monomers are linked together by condensation reactions to form disaccharides and polysaccharide polymers. IB Assessment Statement • List three examples each of monosaccharides, disaccharides and polysaccharides. The examples used should be: glucose, galactose and fructose; maltose, lactose and sucrose; starch, glycogen and cellulose. Sugars: monosaccharides • Monosaccharides have molecular formulas that are usually multiples of CH2O • Monosaccharide is a molecule made up of one type of sugar • Glucose is the most common monosaccharide Monosaccharide: Glucose Copyright Pearson Prentice Hall Monosaccharide: Ribose Copyright Pearson Prentice Hall Disaccharides: Two Sugars • A disaccharide is formed when a dehydration reaction joins two monosaccharides Animation: Disaccharides Disaccharides: Two Sugars • Disaccharide examples: – Lactose formed from a bond between Galactose and glucose Animation: Disaccharides Disaccharides: Two Sugars • Disaccharide examples: – Sucrose formed from a bond between fructose and glucose Animation: Disaccharides Application • Application: Structure and function of cellulose and starch in plants and glycogen in humans. Skill: • Use of molecular visualization software to compare cellulose, starch and glycogen. Polysaccharides: Many Sugars • Starch – Formed from many glucose molecules – Used for energy storage in plants Animation: Disaccharides Polysaccharides: Many Sugars • Glycogen – Formed from many glucose molecules – Energy storage for animals Animation: Disaccharides Polysaccharides: Many Sugars • Cellulose – Formed from many glucose molecules – Structural support for plants Animation: Disaccharides Polysaccharide Comparisons Know the structures of the following carbohydrate • Monosaccharides • glucose, galactose, fructose •Disaccharides •maltose, lactose and sucrose •Polysaccharides •Starch, glycogen, cellulose IB Assessment Statement • State one function of glucose, lactose and glycogen in animals, and of fructose, sucrose and cellulose in plants. Carbohydrate functions in Animals • Glucose – used as a substrate for respiration or converted to glycogen for storage. • Lactose – produced by mammary glands and secreted in milk as an important part of the diet of young mammals • Glycogen – energy storage Carbohydrate functions in Plants • Glucose – a product of photosynthesis. • Fructose – produced as an intermediate substrate during glucose breakdown during respiration. Used in production of sucrose • Cellulose – component of cell walls/ structural support in plants • Starch – energy storage Carbohydrate tutorial Click on the Carbohyrdate tutorial below •http://www.wisconline.com/objects/ViewObject.aspx?ID=AP1310 4 IB Assessment Statement • Outline the role of condensation & hydrolysis reaction the relationships between monosaccharides, disaccharides and polysaccharides; Hydrolysis vs. Condensation Hydrolysis Condensation •Adds water •Removes water •Breaks down polymers into monomers •Forms new bonds between monomers forming polymers •Example: Breaks down starch into glucose •Example: glucose and fructose are bonded together to form sucrose Building and Breakdown disaccharides and Polysaccharides • Condensation (dehydration) and Hydrolysis Reactions One Type of Condensation (dehydration) Reactions 1. Occurs between monosaccharide and forms disaccharides and polysaccharides Disaccharides & Dehydration/ Condensation Reaction • When two monosaccharides join together a hydrogen is released from one monosaccharide & a hydroxide is removed from another • Hydrogen and hydroxide bond together to form water Animation: Disaccharides Condensation (dehydration) Reaction in carbohydrates glucose glucose glucose Fructose Starch Sucrose One type of hydrolysis reactions 1. Breakdown of disaccharide or polysaccharides into monosaccharide Flashcards Make a flashcard of the following: 1st side but the name: • • • • • • • • glucose, Lactose Glycogen (describe structure) fructose, sucrose Cellulose (describe structure) Ribose Starch (describe structure) 2nd side put • State one function of glucose, lactose, ribose and glycogen in animals, • and of fructose, sucrose, ribose and cellulose in plants. • Draw/ describe the structure of the molecule Understandings. • Triglycerides are formed by condensation from three fatty acids and one glycerol. Lipids are a diverse group of hydrophobic molecules • Lipids occur in living things as animal fat and plant oils • The unifying feature of lipids is having little or no attraction for water • Lipids are hydrophobic because they consist mostly of hydrocarbons, which form nonpolar covalent bonds • The most biologically important lipids are fats, phospholipids, and steroids Fats and Oils Fats are constructed from two types of smaller molecules: glycerol (an alcohol) and fatty acids • Glycerol is a three-carbon alcohol with a hydroxyl group (--OH) attached to each carbon • A fatty acid consists of a carboxyl group (--COOH) attached to a long carbon skeleton Structure of fat and oils Fatty acid Glycerol • Fats and oils are compounds called triglycerides • In a fat, three fatty acids are joined to glycerol by an ester linkage a triglyceride • In cells, enzymes catalyze the formation of triglyerides, and also the breakdown of glycerides by hydrolysis Below is a figure representing the Structure of Triglycerides Ester linkage Fat molecule (triacylglycerol) IB Assessment Statements • Outline the role of condensation and hydrolysis in the relationships between between fatty acids, glycerol and triglycerides; and between amino acids and polypeptides. Condensation reaction between glycerol & fatty acids form lipids Fatty acid Glycerol Phospholipids • Phospholipids has a similar chemical structure to triglycerides. • In a phospholipid, one of the fatty acids is replaced by a phosphate group (--PO4) • The over structure of a phospholipid consists of – two fatty acids – and a phosphate group – attached to glycerol • The two fatty acid tails are hydrophobic, but the phosphate group and its attachments form a hydrophilic head LE 5-13 Choline Phosphate Glycerol Fatty acids Hydrophilic head Hydrophobic tails Structural formula Space-filling model Phospholipid symbol • When phospholipids are added to water, they selfassemble into a bilayer, with the hydrophobic tails pointing toward the interior • The structure of phospholipids results in a bilayer arrangement found in cell membranes • Phospholipids are the major component of all Cell Membrane Hydrophilic head Hydrophobic tails WATER WATER Lipid Tutorial Below: Click below for the lipid tutorial • http://www.wisconline.com/objects/ViewObject.aspx?ID=AP13 204 Understandings. • Fatty acids can be saturated, monounsaturated or polyunsaturated. • Unsaturated fatty acids can be cis or trans isomers. Mono vs Poly UNSATURATED FATs • Monounsaturated Fats– One double bond in the hydrocarbon chain • Polyunsaturated Fats – More than one double bond exists in the hydrocarbon chain Saturated vs Unsaturated fatty acids • Polyunsaturated fats are hydrogenated or partially hydrogenated, • Hydrogenated means that double bonds in the fatty acid are broken and hydrogen are added. • Poly and Mono Unsaturated fats becomes saturated through the process of hydrogenation. Saturated (trans) vs. Unsaturated (cis) • Mono and Poly Unsaturated fatty acids are naturally curved. • Saturated fatty acids are straight. Trans vs. Cis • Cis fatty acids are unsaturated, contain a double bond in the fatty acid chain and are curved. – An example of a cis fatty acid is Omega -3 • Trans fatty acid are saturated, no double bonds and straight. – Vast majority of trans fatty acid are the result of food process (i.e. hydrogenation) CHD is coronary heart disease Why are Trans fats bad? VIDEOS • Simple video – https://www.youtube.com/watch?v=mYM7B2RfpdE • GOOD VIDEO BELOW: – https://www.youtube.com/watch?v=7kLLI2GluDE • Lipid Video – https://www.youtube.com/watch?v=ulIjtl4FPDQ • Biochemistry & human physiology of fat in the blood ( 1 hour long lecture) – https://www.youtube.com/watch?v=_oLXa4SfsVs Omega-3 and Omega 6 Fatty Acids The name omega 3 and omega 6 comes from which numbered carbon has the double bond. Nature of Science • Evaluating claims—health claims made about lipids in diets need to be assessed. (5.2) Why are Trans fats bad? • The Shape of trans fats make them bad for your cardiovascular system. – Saturated trans fats are linear and thus they lay flat against your arteries making is more difficult for them to flow with your passing blood. – These linear, saturated, trans fatty acids combine with cholesterol and form a substance called plaque and can be deposited along the walls of your arteries blocking or slowing blood flow. It this happens in the coronary arteries you can have a heart attack. Application • Application: Lipids are more suitable for longterm energy storage in humans than carbohydrates. Energy Content in Food • Fats contain more than twice as much energy per 100 grams than carbohydrates and proteins • Carbohydrates: 1,760 kJ per 100 g • Proteins: 1,720 kJ per 100 g • Fats: 4,000 kJ per 100 g Skills • Determination of body mass index by calculation or use of a nomogram. • A.2.5 Calculate body mass index (BMI) from the body mass and height of a person • A.2.6 Distinguish, using the body mass index, between being underweight, normal weight, overweight and obese • • Underweight – below 18.5 weight – 18.5 to 24.9 • • Overweight – 25 to 29.9 above 30.0 • Normal • Obese – Body Mass Index