Lecture 1
Analytical Chemistry CHE301
Synthetic Chemistry
To make a new stuff
Analytical Chemistry
To find out what is it
“white powder”
Qualitative
to identify
This white powder is
NaCl
to detect
There is a trace
admixture
of iodine in this
sample
Quantitative
to analyze
to determine X in a sample
to quantify
to measure
0.375 mg/mL caffeine
Run
assay
determination
quantitation
Composition, %%:
Cu, 85.34(3); Zn, 11.23; Sn, 1.02(2);
Fe, 0.123(2); Mn, 0.058(5); Ni, 0.229(5); …
Analytical chemistry sequence @ BSC
Titrations with NaOH, EDTA, KMnO4, K2Cr2O7, , I2
CHE111-112
CHE203-204
CHE301
CHE403
Some separations and photometry
Identification of organic compounds; IR, NMR, GC
Analytical Chemistry itself: gravimetry, titrations,
electrochemistry and spectrophotometry
Instruments, how they work and how to operate them
Biochemistry, Advanced Analytical Chemistry,
Analytical Toxilcology, and Inorganic Chemistry
- More about analytical methods
Analytical problems and procedures
Definition of the problem
Chice of technique
Sampling
Sample pre-treatment
Preliminary qualitative tests
Quantitative analysis
Reporting the results
Review of the original problem
An example from Harris:
A chocolate story: how much caffeine?
Garbage in,
Garbage out!
Calibration