Introduction to
Analytical
Chemistry
Dr Carl Hall
X1/12
c.e.hall@hud.ac.uk
SFC1004
Analytical Science 1
What is Analytical Chemistry?

The resolution of a chemical
compound into its proximate or
ultimate parts; the determination of
its elements or of the foreign
substances it may contain.
What is Analytical Chemistry?

Qualitative Analysis

Quantitative Analysis
What is Analytical Chemistry?

Qualitative analysis
 The
determination of the
components of an unknown
sample.
 Organic
spectroscopy
What is Analytical Chemistry?

Quantitative analysis
 The
determination of the
quantity of the components in
a sample.
 Classical
methods
What is Analytical Chemistry?
Forensic Science
Medicine
Materials Science
Physics
Analytical
Science
Biochemistry
Physical Chemistry
Organic Chemistry
Applications

Fundamental Research
 The
formulation of new drugs and the
examination of meteorites.

Product Development
 Development

of alloys and polymer composites.
Product Quality Control
 Analysis
of raw materials and finished products.
Applications

Monitoring and Control of Pollutants
 Heavy

Assay
 The

metals and pesticides.
metal content of ores.
Medical and Clinical Studies
 Indicators

of physiological disorders.
Food Analysis
 Labelling
and provenance
Glossary of Terms
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Accuracy
Analyte
Assay
Background
Blank
Calibration
Concentration
Constituent
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Detection Limit
Determination
Equivalent
Estimation
Interference
Internal Standard
Masking
Matrix
Glossary of Terms
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Method
Precision
Primary Standard
Procedure
Reagent
Sample
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Sensitivity
Standard
Standard Addition
Standardisation
Technique
Validation
Analytical Techniques

Chemical analysis is an indispensable
servant of modern technology whilst it
partly depends on that modern technology
for its operation.

The two have developed hand in hand.
Analytical Techniques

Classical Techniques

Instrumental Techniques

Historically derived and artificial
Analytical Techniques
Analytical Problems and their
Solution

The solutions of all analytical
problems, both qualitative and
quantitative follow the same basic
pattern which can be described under
seven general headings.
Analytical Problems and their
Solution
Choice of method
 Sampling
 Preliminary sample treatment
 Separations
 Final measurement
 Method validation
 Assessment of the results
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