Principles of Electrical Currents HuP 272 Electricity is an element of PT modalities most frightening and least understood. Understanding the basis principles will later aid you in establishing treatment protocols. General Therapeutic Uses of Electricity Controlling acute and chronic pain Edema reduction Muscle spasm reduction Reducing joint contractures Minimizing disuse/ atrophy Facilitating tissue healing Strengthening muscle Facilitating fracture healing Contraindications of Electrotherapy Cardiac disability Pacemakers Pregnancy Menstruation (over abdomen, lumbar or pelvic region) Cancerous lesions Site of infection Exposed metal implants Nerve Sensitivity Terms of electricity Electrical current: the flow of energy between two points Needs A driving force (voltage) some material which will conduct the electricity Amper: unit of measurement, the amount of current (amp) Conductors: Materials and tissues which allow free flow of energy Fundamentals of Electricity Electricity is the force created by an imbalance in the number of electrons at two points Negative pole an area of high electron concentration (Cathode) Positive pole and area of low electron concentration (Anode) Charge An imbalance in energy. The charge of a solution has significance when attempting to “drive” medicinal drugs topically via inotophoresis and in attempting to artificially fires a denervated muscle Charge: Factors to understand Coulomb’s Law: Like charges repel, unlike charges attract Like charges repel allow the drug to be “driven” Reduce edema/blood Charge: Factors Membranes rest at a “resting potential” which is an electrical balance of charges. This balance must be disrupted to achieve muscle firing Muscle depolarization is difficult to achieve with physical therapy modalities Nerve depolarization occurs very easily with PT modalities Terms of electricity Insulators: materials and tissues which deter the passage of energy Semiconductors: both insulators and conductors. These materials will conduct better in one direction than the other Rate: How fast the energy travels. This depends on two factors: the voltage (the driving force) and the resistance. Terms of electricity Voltage: electromotive force or potential difference between the two poles Voltage: an electromotive force, a driving force. Two modality classification are: Hi Volt: greater than 100-150 V Lo Volt: less than 100-150 V Terms of electricity Resistance: the opposition to flow of current. Factors affecting resistance: Material composition Length (greater length yields greater resistance) Temperature (increased temperature, increase resistance) Clinical application of Electricity: minimizing the resistance Reduce the skin-electrode resistance Minimize air-electrode interface Keep electrode clean of oils, etc. Clean the skill on oils, etc. Use the shortest pathway for energy flow Use the largest electrode that will selectively stimulate the target tissues If resistance increases, more voltage will be needed to get the same current flow Clinical application of Electricity: Temperature Relationship An increase in temperature increases resistance to current flow Applicability Preheating the tx area may increase the comfort of the tx but also increases resistance and need for higher output intensities Clinical Application of Electricity: Length of Circuit Relationship: Greater the cross-sectional area of a path the less resistance to current flow Application: Nerves having a larger diameter are depolarized before nerves having smaller diameters Clinical Application of Electricity: Material of Circuit Not all of the body’s tissues conduct electrical current the same Excitable Tissues Nerves Muscle fibers blood cells cell membranes Non-excitable tissues Bone Cartilage Tendons Ligaments Current prefers to travel along excitable tissues Stimulation Parameter: Amplitude: the intensity of the current, the magnitude of the charge. The amplitude is associated with the depth of penetration. The deeper the penetration the more muscle fiber recruitment possible remember the all or none response and the Arndt-Schultz Principle Simulation Parameter Pulse duration: the length of time the electrical flow is “on” also known as the pulse width. It is the time of 1 cycle to take place (will be both phases in a biphasic current) phase duration important factor in determining which tissue stimulated: if too short there will be no action potential Stimulation Parameter: Pulse rise time: the time to peak intensity of the pulse (ramp) rapid rising pulses cause nerve depolarization Slow rise: the nerve accommodates to stimulus and a action potential is not elicited Good for muscle reeducation with assisted contraction - ramping (shock of current is reduced) Stimulation Parameters Pulse Frequency: (PPS=Hertz) How many pulses occur in a unit of time Do not assume the lower the frequency the longer the pulse duration Low Frequency: 1K Hz and below (MENS .1-1K Hz), muscle stim units) Medium frequency: 1K ot 100K Hz (Interferential, Russian stim LVGS) High Frequency: above 100K Hz (TENS, HVGS, diathermies) Stimulation Parameter: Current types: alternating or Direct Current (AC or DC) AC indicates that the energy travels in a positive and negative direction. The wave form which occurs will be replicated on both sides of the isoelectric line DC indicated that the energy travels only in the positive or on in the negative direction DC AC Stimulation Parameter: Waveforms; the path of the energy. May be smooth (sine) spiked, square,, continuous etc. Method to direct current Peaked - sharper Sign - smoother Stimulation Parameter: Duty cycles: on-off time. May also be called inter-pulse interval which is the time between pulses. The more rest of “off” time, the less muscle fatigue will occur 1:1 Raito fatigues muscle rapidly 1:5 ratio less fatigue 1:7 no fatigue (passive muscle exercise) Stimulation Parameter: Average current (also called Root Mean Square) the “average” intensity Factors effective the average current: • pulse amplitude • pulse duration • waveform (DC has more net charge over time thus causing a thermal effect. AC has a zero net charge (ZNC). The DC may have long term adverse physiological effects) Stimulation Parameter: Current Density The amount of charge per unit area. This is usually relative to the size of the electrode. Density will be greater with a small electrode, but also the small electrode offers more resistance. Capacitance: The ability of tissue (or other material) to store electricity. For a given current intensity and pulse duration The higher the capacitance the longer before a response. Body tissues have different capacitance. From least to most: Nerve (will fire first, if healthy) Muscle fiber Muscle tissue Capacitance: Increase intensity (with decrease pulse duration) is needed to stimulate tissues with a higher capacitance. Muscle membrane has 10x the capacitance of nerve Factors effecting the clinical application of electricity Factors effecting the clinical application of electricity Rise Time: the time to peak intensity The onset of stimulation must be rapid enough that tissue accommodation is prevented The lower the capacitance the less the charge can be stored If a stimulus is applied too slowly, it is dispersed Factors effecting the clinical application of electricity An increase in the diameter of a nerve decreased it’s capacitance and it will respond more quickly. Thus, large nerves will respond more quickly than small nerves. Denervated muscles will require a long rise time to allow accommodation of sensory nerves. Best source for denervated muscle stimulation is continuous current DC Factors effecting the clinical application of electricity: Ramp: A group of waveforms may be ramped (surge function) which is an increase of intensity over time. The rise time is of the specific waveform and is intrinsic to the machine. Law of DuBois Reymond: The amplitude of the individual stimulus must be high enough so that depolarization of the membrane will occur. The rate of change of voltage must be sufficiently rapid so that accommodation does not occur The duration of the individual stimulus must be long enough so that the time course of the latent period (capacitance), action potential, and recovery can take place Muscle Contractions & Frequency Are described according to the pulse width 1 pps = twitch 10 pps = summation 25-30 pps = tetanus (most fibers will reach tetany by 50 pps) Frequency selection: 100Hz - pain relief 50-60 Hz = muscle contraction 1-50 Hz = increased circulation The higher the frequency (Hz) the more quickly the muscle will fatigue Frequency selection: 100Hz - pain relief 50-60 Hz = muscle contraction 1-50 Hz = increased circulation The higher the frequency (Hz) the more quickly the muscle will fatigue Electrodes used in clinical application of current: Electrodes used in clinical application of current:At least two electrodes are required to complete the circuit The body becomes the conductor Monophasic application requires one negative electrode and one positive electrode The strongest stimulation is where the current exists the body Electrodes placed close together will give a superficial stimulation and be of high density Electrodes used in clinical application of current: Electrodes spaced far apart will penetrate more deeply with less current density Generally the larger the electrode the less density. If a large “dispersive” pad is creating muscle contractions there may be areas of high current concentration and other areas relatively inactive, thus functionally reducing the total size of the electrode A multitude of placement techniques may be used to create the clinical and physiological effects you desire General E-Stim Parameters Pain Edema Muscle Re-ed. Tissue Healing Hz: 100+ Tens, HVGS, IFC Hz: 100-150 HVGS, IFC Hz: 50-60 Type: depends on purpose Hz: 100+ or 1(? inc. circ) IFC, Ionto, Mens (?) PPS: 70-100 Polarity: purpose & comfort PPS: 120 Polarity: negative PPS: 1-20 Polarity: purpose & comfort PPS: vary but typically tens like Polarity: purpose & comfort Time: 20-60 min Time: 20 min Time: Fatigue (1-15 min) Time: 20 min Other: Electrode Spacing Burst Option, Voltage/Acc. Accupoint (1-5pps) Other: Electrode Spacing Voltage/Acc. With muscle cxn or pain reduction Other: Electrode Spacing, surge Burst Option, Voltage/Acc. Accupoint (1-5pps) Other: Electrode Spacing Voltage/Acc. Accupoint E-Stim for Pain Control: typical Settings Neuromuscular Stimulation High Volt Pulsed Stim Gate Control Theory High-Volt Pulsed Stim Opiate Release High-Volt Pulsed Stim Brief-Intense (Probe) High-Volt Pulsed Stim Intensity: Stong & comfortable Intensity: Sensory Intensity: Motor level Intensity: Noxious Type title here Pulse Rate: <15 35-50 for tonic contraction Pulse Rate: 60-100 pps Pulse Rate 2-4 pps Pulse Rate: 120pps Polarity: + or - Phase Duration < 100 usec Phase Duration: 150-250 usec Phase Duration: 300-1000 usec Alternating Rate: Alternating Mode: continuous Mode: Continuous Mode: 15-60 sec at each site Electrode Placement Biopolar: Distal & Proximal to muscle Monopolar: Over motor points Electrode Placement Directly over motor points Electrode Placement Directly over motor points Electrode Placement Grid Tech: distal & proximal to site High Volt Pulsed Stimulation CURRENT CONCEPTS EVIDENCE BASED ES increased 20% verses control (no activity) demonstrating that ES “can alter the blood flow in muscle being stimulated” Currier et all 1996 Currier et al 1988: Similar study but 15% Bettany et al 1990: Edema formation in frogs decreased with HVPC 10 minutes after the trauma CURRENT CONCEPTS EVIDENCE BASED Walker et al 1988: HVS at a pulse rate of 30 Hz and intensities to evoke 10% - 20% MVC did not increase blood flow to the popliteal artery. The exercise group demonstrated 30% increase Von Schroeder et al 1991: Femoral venous flow shown to increase greatest with passive SLR elevation, then CPM, active ankle dorsiflexion, manual calf compression and passive dorsiflexion HVPS The application of monophasic current with a known polarity typically a twin-peaked waveform duration of 5 - 260 msec Wide variety of uses: muscle reeducation (requires 150V) nerve stimulation (requires 150V) edema reduction pain control Clinical Application: Physiological response can be excitatory and non-excitatory Excitatory Peripheral nerve stimulation for pain modulation (sensory, motor and pain fibers) Promote circulation: inhibits sympathetic nervous system activity, muscle pumping and endogenous vasodilatation Non-Excitatory (cellular level) Protein synthesis Mobilization of blood proteins Bacteriocyte affects (by increased CT micro-circulation there is a reabsorption of the interstitial fluids) General Background Early in history HVS was called EGS, then HVGS, then HVPS Current qualifications to be considered HVS Must have twin peak monophasic current Must have 100 or 150 volts (up to 500 V) HVPS Precautions Stimulation may cause unwanted tension on muscle fibers Muscle fatigue if insufficient duty cycle Improper electrodes can burn or irritate Intense stim may result in muscle spasm or soreness Contraindications Cardiac disability Pacemakers Pregnancy Menstruation Cancerous lesion Infection Metal implants Nerve sensitivity Indications past slide Treatment Duration General - 15-30 minutes repeated as often as needed Pain reduction - sensory 30 minutes with 30 minute rest between tx Current Parameters greater than 100-150 V usually provides up to 500 V high peak, low average current strength duration curve = short pulse duration required higher intensity for a response high peak intensities (watts) allow a deeper penetration with less superficial stimulation Current Parameters Pulse Rate: ranges from 1-120 pps varies according to the desire clinical application Current Pulse Charge related to an excess or deficiency of negatively charged particles associated with the beneficial or harmful responses (thermal, chemical, physical) Modulations intrapulse spacing duty cycle: reciprocal mode usually 1:1 ratio ramped or surged cycles Clinical Considerations: always reset intensity after use (safety) electrode arrangements may be mono or bipolar units usually have a hand held probe for local (point) stimulation most units have an intensity balance control Application Techniques Monopolar: 2 unequal sized electrodes. Smaller is generally over the treatment site and the large serves as a dispersive pad, usually located proximal to the treatment area Bipolar: two electrodes of equal size, both are over or near the treatment site Water immersion - used for irregularly shaped areas Probes: one hand-held active lead advantages: can locate and treat small triggers disadvantages: one on one treatment requires full attention of the trainer Electrodes Material carbon impregnated silicone electrodes are recommended but will develop hot spots with repeated use you want conductive durable and flexible material tin with overlying sponge has a decreased conformity and reduced conductivity Electrodes Size based on size of target area current density is important. The smaller the electrode size the greater the density Neuromuscular Stimulation Roles: re-educate a muscle how to contract after immobilization (does not produce strength augmentation but retards atrophy) Parameter Setting Intensity Strong, comfortable Pulse frequency Polarity Muscle cxn <15pps Tonic cxn 35-50 pps + or - Alternation Yes Pain Control Roles: Control acute or chronic pain both sensory (gate control 100-150 pps)) and motor level (opiate release - through voltage) Parameter Intensity Setting for Gate Control Method Sensory Pulse frequency Phase Duration Mode 60-100 pps Continuous Placement Directly over pain site < 100sec Pain Control - Opiate Release Setting Parameter Intensity Phase Duration Pulse frequency Mode Setting Opiate Release Motor Level 150V 150-250 msec 2-4pps Continuous Placement Directly over pain site Evidence Based Clinical Studies on HVPC and pain modulation is misleading – pain associated with muscle spasm is decreased secondary to muscle fatigue/exhaustion (Belanger, 2003) Studies on muscle strengthening have indicated no effect (Alon 1985, Mohr et al, 1985; Wong 1986) Control and Reduction of Edema Roles: Sensory level used to limit acute edema Motor-level stimulation used to reduce subacute or chronic inflammation Parameter Setting Sensory Level Control Intensity Sensory Pulse frequency Polarity 120 pps Pulse Duration Mode Maximum allowed by generator - Continuous Motor-Level Edema Reduction Cell Metabolism: increased and may increase blood flow Wound Healing: May increase collagnase levels and inhibit bacteria in infected wounds (for this effect 20 min - polarity followed by 40 min + polarity recommended) Parameter Setting Intensity Strong, comfortable Pulse frequency Polarity Low 2-4 pps Alternation Yes + or - Russian Current Continuous sine-wave modulation of 2,5000 pps and burst-modulated for fixed periods of 10 msec resulting in a frequency of 50 bursts per second. Thought to depolarize both sensory and motor concomitantly (knots 1977). Thus simulating muscle training. No North American has been able to duplicate Knots’ claims T.E.N.S. General Concepts: An Approach to pain control Trancutaneous Electrical Nerve Stimulation: Any stimulation in which a current is applied across the skin to stimulate nerves 1965 Gate Control Theory created a great popularity of TENS TENS has 50-80% efficacy rate TENS stimulates afferent sensory fibers to elicit production of neurohumneral substances such as endorphins, enkephalins and serotonin (i.e. gate theory) TENS Indications Control Chronic Pain Management postsurgical pain Reduction of posttraumatic & acute pain Precautions Can mask underlying pain Burns or skin irritation prolonged use may result in muscle spasm/soreness caffeine intake may reduce effectiveness Narcotics decrease effectiveness Research is variable regarding the benefits of TENS Therapy (see Table 2-2; Belanger, 2001) TENS may be: high voltage interferential acuscope low voltage AC stimulator classical portable TENS unit Biophysical Effects Primary use is to control pain through Gate Control Theory (between 0-100% can be placebo effect (Thorsteinsson et al., 1978, Wall,1994) Opiate pain relief through stimulation of naloxone (antagonist to endogenous opiates) May produce muscle contractions Various methods High TENS (Activate A-delta fibers) Low TENS (release of -endorphins from pituitary) Brief-Intense TENS (noxious stimulation to active C fibers) Techniques of TENS application: Conventional or High Frequency Short Duration , high frequency and low to comfortable current amplitude Only modulation that uses the Gate Control Theory (opiate all others) Acupuncture or Low Frequency Long pulse duration, Low frequency and low to comfortable current amplitude Brief Intense Long pulse duration, high frequency, comfortable to tolerable amplitude Burst Mode Burst not individual pulses, modulated current amplitude Modulated Random electronic modulation of pulse duration, frequency and current amplitude Protocol for Various Methods of TENS Parameter High TENS Low TENS Intensity Sensory Motor Brief-Intense TENS Noxious Pulse Fq 60-100 pps 2-4 pps Variable Pulse Duration Mode 60-100 sec 150-250 sec Modulated Tx Duration As needed Modulated Burst 30 min Onset of Relief < 10 min 20-40 min 300-1000sec Modluated <15 min 15-30 min Conventional Tens/High Frequency TENS Paresthesia is created without motor response A Beta filers are stimulated to SG enkephlin interneuron (pure gate theory) Creates the fastest relief of all techniques Applied 30 minutes to 24 hours relief is short lives (45 sec 1/2 life) May stop the pain-spasms cycle Application of High TENS Pulse rate: high 75-100 Hz (generally 80), constant Pulse width: narrow, less than 300 mSec generally 60 microSec Intensity: comfortable to tolerance Set up: 2 to 4 electrodes, often will be placed on post-op. Readjust parameters after response has been established. Turn on the intensity to a strong stimulation. Increase the pulse width and ask if the stimulation is getting wider (if deeper=good, if stronger...use shorter width) Low Frequency/Acupuncture-like TENS: Level III pain relief, A delta fibers get Beta endorphins Longer lasting pain relief but slower to start Application pulse rate low 1-5ppx (below 10) Pulse width: 200-300 microSec Intensity: strong you want rhythmical contractions within the patient’s tolerance Burst Mode TENS Carrier frequency is at a certain rate with a built in duty cycle Similar to low frequency TENS Carrier frequency of 70-100 Hz packaged in bursts of about 7 bursts per second Pulses within burst can vary Burst frequency is 1-5 bursts per second Strong contraction at lower frequencies Combines efficacy of low rate TENS with the comfort of conventional TENS Burst Mode TENS - Application Pulse width: high 100-200 microSec Pulse rate: 70-100 pps modulated to 1-5 burst/sec Intensity: strong but comfortable treatment length: 20-60 minutes Brief, Intense TENS: hyperstimulation analgesia Stimulates C fibers for level II pain control (PAG etc.) Similar to high frequency TENS Highest rate (100 Hz), 200 mSec pulse width intensity to a very strong but tolerable level Treatment time is only 15 minutes, if no relief then treat again after 2-3 minutes Mono or biphasic current give a “bee sting” sensation Utilize motor, trigger or acupuncture points. Brief Intense TENS - Application Pulse width: as high as possible Pulse rate: depends on the type of stimulator Intensity: as high as tolerated Duration: 15 minutes with conventional TENS unit. Locus stimulator is advocated for this treatment type, treatment time is 30 seconds per point. Locus point stimulator Locus (point) stimulators treatment occurs once per day generally 8 points per session Auricular points are often utilized Treat distal to proximal Allow three treatment trails before efficacy is determined Use first then try other modalities Modulated Stimulation: Keeps tissues reactive so no accommodation occurs Simultaneous modulation of amplitude and pulse width As amplitude is decreased, pulse width is automatically increased to deliver more consistent energy per pulse Rate can also be modulated Electrode Placement: May be over the painful sites, dermatomes, myotomes, trigger points, acupuncture points or spinal nerve roots. May be crossed or uncrossed (horizontal or vertical Contraindications: Demand pacemakers over carotid sinuses Pregnancy Cerebral vascular disorders (stroke patients) Over the chest if patient has any cardiac condition Interferential Current - IFC Interferential Current History: In 1950 Nemec used interference of electrical currents to achieve therapeutic benefits. Further research and refinements have led to the current IFC available today Two AC are generated on separate channels (one channel produces a constant high frequency sine wave (40005000Hz) and the other a variable sine wave The channels combine/interface to produce a frequency of 1100 Hz (medium frequency) Evidence Based: Although IFC has been used for 40 years, only a few clinical studies have been published regarding use (DeDomenico, 1981,1987; Savage, 1984; Nikolova, 1987). Effects of IFC treatment: Primary Physiological Effect: Capacity of IFC to depolarize Sensory and motor nerve fibers Main Therapeutic Effects Sensory nerve fibers - Pain reduction - receive a lower amplitude stimulation than the area of tissue affected by the vector, thus IFC is said to be more comfortable than equal amplitudes delivered by conventional means Blood flow/edema management Muscle fatigue - muscle spasm - is reduced when using IFC versus HVS due to the asynchronous firing of the motor units being stimulated Positive effects of IFC include: reduction of pain and muscle discomfort following joint or muscle trauma these effects can be obtained with the of IFC and without associated muscle fatigue which may predispose the athlete to further injury. Evidence Based Research Low frequency This has been claimed as the key to IFC (Savage, 1984, Nikolova, 1987) Palmer, 1999: IFC unlikely to produce physiological and therapeutic effects different from those achieved by TENS Alon, 1999 states that IFC simply provides a more expensive, different, least effective and somewhat redundant approach to achieving the same effects as other electrical stimulation parameters/waveforms Pain sensation: Although the physiological changes are not different with IFC, Pain perception is decreased with IFC (Palmer, 1999) Evidence Based Literature: IFC does not lower skin impedance (Alon, 1999; Gerleman et al, 1999) Any pulsed biphasic current, regardless of waveform, having a medium frequency are capable of a deeper stimulating effect (Alon, 1999; Hayes, 2000; Kloth, 1991;) Snyder-Mackler, et al 1989) Increased Circulation is an anecdotal claim and has not been recreated in studies (Bersglien et al, 1988; Indergand et al.k 1995; Johnson, 1999; Nusswbaum et al., 1990: Olson et al., 1999) Analgesic Effect: Similar not superior to other stimulations (TENS) (DeDomenico, 1982, 1987; Nikolova, 1987; Savage, 1984) Stephenson et al., 1995: Superior to a control group with ice/pain Cramp et al., 2000: Failed to demonstrate any effective pain relief with IFC Principles of wave interference Combined Effects Constructive, Destructive, & Continuous Constructive interference: when two sinusoidal waves that are exactly in phase or one, two, three or more wavelengths our of phase, the waves supplement each other in constructive interference + = Principles of wave interference Combined Effects Destructive interference: when the two waves are different by 1/2 a wavelength (of any multiple) the result is cancellation of both waves + = Principles of wave interference Combined Effects Continuous Interference Two waves slightly out of phase collide and form a single wave with progressively increasing and decreasing amplitude + = Amplitude-Modulated Beats: Rate at which the resultant waveform (from continuous interference) changes When sine waves from two similar sources have different frequencies are out of phase and blend (heterodyne) to produce the interference beating effect IFC Duration of tx 15-20 minutes Burst mode typically applied 3x a week in 30 minute bouts Precautions same as all electrical currents Contraindications Pain of central origin Pain of unknown origin Indications Acute pain Chronic pain Muscle spasm IFC Techniques of treatment: Almost exclusively IFC is delivered using the four-pad or quad-polar technique. Various electrode positioning techniques are employed: Electrodes (Nemectrody: vacuum electrodes): four independent pads allow specific placement of pads to achieve desired effect an understanding of the current interference is essential four electrodes in one applicator allows IFC treatment to very small surface areas. The field vector is predetermined by the equipment Quad-polar Technique Pads placed at 45º angles from center of tx area Can reduce inaccuracy of appropriate tissues by selecting rotation or scan Channel B Channel B Channel A Channel A SCAN Bipolar Electrode Placement The mix of two channels occurs in generator instead of tissues Biopolar does not penetrate tissues as deeply, but is more accurate When effects are targeted for one muscle or muscle group only one channel is used Two-circuit IFC: At other points along the time axes the wave amplitude will be zero because the positive phase from one circuit cancels the negative phase from the second circuit (destructive interference) The rhythmical rise and fall of the amplitude results in a beat frequency and is equal to the number of times each second that the current amplitude increases to its maximum value and then decreases to its minimum value Special Modulations of IFC: Constant beat frequencies (model): the difference between the frequencies of the two circuits is constant and the result is a constant beat frequency. That is, if the difference in frequency between the two circuits is 40 pps, the beat frequency will be constant at 40 bps. Special Modulations of IFC: Variable beat mode: the frequency between the two circuits varies within preselected ranges. The time taken to vary the beat frequency through any programmed range is usually fixed by the device at about 15 sec. IFC machines often allow the clinician to choose from a variety of beat frequency programs. Pain Control Similar to TENS - beat frequency 100Hz • Low beat frequencies when combined with motor level intensities (2-10Hz) initiate the release of opiates • 30 Hz frequencies affects the widest range of receptors Parameter Range Intensity Sensory Electrode Config Quadpolar Beat Fq High – Gate Control Low – Opiate release Long Duration Sweep Fq Neuromuscular Stimulation Beat frequency of approximately 15 HZ is used to reduce edema General Parameters Parameter Range Intensity 1-100mA Carrier Fq 2500-5000Hz Beat Fq 0-299 Hz Sweep Fq 10-500sec IFC Technique of treatment: Electrode placement: The resultant vector should be visualized in placing the electrodes for a treatment . The target tissue should be identified and the vector positioned to hit that area. Typically at 45º angles is most effective. Segregation of the pin tips is essential in the proper electrode positioning for IFC. The electrodes may be of the same size or two different sizes (causing a shift in the intersecting vector). Treatment through a joint has also been advocated without adequate research to establish efficacy of the treatment technique. Bone Stimulating Current: Bone Stimulating Current:Bone Stimulating Current:IFC has been used (Laabs et al) studied the healing of a surgically induced fracture in the forelegs of sheep. Their study indicated an acceleration of healing in the sheep treated with IFC as compared to the control group Bone Stimulating Current: This study validated an earlier study by Gittler and Kleditzsch which showed similar results in callus formation in rabbits. Several other studies have shown an increase in the healing rate of fractures but the exact mechanism by which the healing occurs is not understood. Bone Stimulating Current: Some speculation is that an increased blood flow to the injured area is produced which allowed natural healing processes to occur more rapidly. In one study (mandible fractures ) the IFC caused very mild muscle contraction of the jaw and this muscle activity was thought to have been a potential accelerator of the healing. MENS or LIDC (low-intensity direct current) MENS No universally accepted definition or protocol & has yet to be substantiated This form of modality is at the sub-sensory or very low sensory level current less than 1000A (approx 1/1000 amp of TENS) Theorized that this is the current of injury (Becker et al 1967, Becker & Seldon, 1987) Biophysical Effects Theory: Currents below 500A increases the level of ATP (high Amp decreases ATP levels) Increase in ATP encourages amino acid transport and increased protein synthesis MENS reestablishes the body’s natural electrical balance allowing metabolic energy for healing without shocking the system (other types of e-stim) Studies conducted indicate no difference from control group for wound healing MENS Duration 30 min to 2 hours up to 4x a day Research suggests high degree of variability on tx protocols Precautions Dehydrated patients on Scar tissue (too much impedance) Contraindications Pain of unknown origin Osteomyelitis Inconclusive Data: DOMS as an indication (Allen et al 1999, Weber et al 1994) Indications Acute & Chronic Pain Acute & Chronic Inflammation Edema reduction sprains & Strains Contusion TMJ dysfunction Neuropathies Superficial wound healing Carpal Tunnel Syndrome Electrode Placement Electrodes should be placed in a like that transects the target tissues Remember that electrical current travels in path of least resistance, thus it is not always a straight line. TARGET Either the + or – electrode can be placed on the injured tissue (Research is inconclusive: Lampe 1998, Sussmen et al 1999) Suggest alternating + and - electrode Application Techniques Standard electrical stimulation pads generator may have bells & Whistles since MENS is sub-sensory Probe Bone Stimulating Current: MENS Has been advocated in the healing of bone, using implanted electrodes and delivering a DC current with the negative pole at the fracture site. Further use of MENS has allowed increased rate of fracture healing using surface electrodes in a noninvasive technique. Theories on the physiology behind the healing focus on the electrical charge present in the normal tissue as compared to the electrical charge found with the injured tissue. MENS is said to allow an induction of an electrical charge to return to he tissues to a better “healing” environment Research on bone stimulating current is inconclusive. Iontophoresis Iontophoresis: Categorized as continuous direct electric current The transfer of ions across the skin (transdermal)by use of continuous direct current Iontophoresis is based on the principle that an electrically charged electrode will repel a similarly charged ion (first reported by LeDuc in 1903). This is pore dependant (Banga et al 1998) Delivers a low-volt High-amp DC current Local blood flow is increased for 1 hour post tx Iontophoresis Duration of Tx: Based on intensity desired usually every other day for 3 weeks Indications Acute or Chronic Inflam Arthritis Myositis Myofacial Pain Syndromes Invasive method for delivering drugs Contraindications Hypersensitivity to electrical currents Contraindications to meds. Pain of unknown origin Precautions Prescription Dosage Do not reuse electrode Burns if intensity to great Iontophoresis Effects of treatment depends on the ion(s) delivered musculoskeletal inflammatory conditions (tendonitis, bursitis) have been successfully treated: Using desamethosone sodium phosphate (decadron) and Xylocaine Reduction of edema has been achieved by driving hyaluronidase Transitory (5min) local anesthesia has been produced by delivering lidocaine to the tissues. The anesthesia was better than that achieved by topical application but less effective than infiltration of the area with lidocaine. Medication Dosage Medication dose delivered during tx is measured in mA based on relationship of amperage, tx duration Current Amp (mA) x Tx Duration - mA/min Iontophoresors are dose-oriented - where user indicated desired tx does and generator calculated duration and intensity Indications – evidence based Condition Ions Benefit Reference Yes Kahn, 1982, Reidle et all 2000, Montorsi et all 2000, Rothfield et al 1967 Inflamm. Disorders Dex Musc. Yes Bertolucci, 1982, Delacerda, 1982Harris, 1982, Pellecchia et al 1994, TMJ Dex & dex/lido Yes Braun 1987; Reid et al 1994;Schiffman et al 1996 TMJ Epicondylitis Hydrocort/US Dex No No Kahn, 1980 Epicondylitis Carpal tunnel Edema Na+ Salcycil. Dex Hualuronidase Yes Yes Yes Demiratas et al 1998 Plantar Faciitis Dex/lido. Panus et al 1996 Banta, 1994 Magistro 1964, Boone 1969 Iontophoresis: Evidence Based Condition Ions Benefit Reference Scar Tissue Iodine Yes Tennenbaum, 1980 Tendon Adhesion Iodine Yes Langley 1984 Subdeltoid Bursa Magnesium Yes Weinstein et al 1958 Plantar warts Heel Pain Salicylate Acetate Yes Yes Gordon et al 1969 Myositis Oss. Acetate Yes Weider, 1992 Myopathy Postsurgical hip pain Calcium Salicylate ? Yes Kahn, 1975 Japour et al, 1999 Garzione, 1978 Biophysical Effects Dependant on Medication See following chart Sample Medications Meds Pathology Dose Polarity Acetic Acid Myositis 80mA/min + Dexamethasone Inflammation 41mA/min & Lidocain & Pain control & 40 mA - Lidocain & Epinphrine Pain Control 30mA/min + Lidocain & Epinphrine Pain Control 20 mA/min + Dexamethasone Inflammation 41mA/min - Electrode Placement Delivery Electrode (drug electrode) placed over target tissue Active electrode (dispersive electrode) place 4-6 inches from drug electrode Side Effects: Tissue “burning” An alkaline reaction occurs under the cathode (negative electrode) which is much more caustic to the skin than the acidic reaction occurring at the anode. The cathode may be increased in size to attempt to decrease this caustic reaction Side Effects: Tissue “burning” Continuous unidirectional current (as needed for iontophoresis) tends to cause tissue irritation because skin will not tolerate current density greater than 1mA/sq.cm. Thin tissue areas, areas of skin abrasion and areas of scarring are certain areas to avoid. This potential for burn is exacerbated by the fact that there is an anesthetic effect of DC under the electrode. Thus tissue irritation may develop without the patient’s realization Don’t need to drive every day 1-2x a week